Search Results - "Mohammed, Hamada H.H."

New antiproliferative 7-(4-(N-substituted carbamoylmethyl)piperazin-1-yl) derivatives of ciprofloxacin induce cell cycle arrest at G2/M phase by Mohammed, Hamada H.H., Abd El-Hafeez, Amer Ali, Abbas, Samar H., Abdelhafez, El-Shimaa M.N., Abuo-Rahma, Gamal El-Din A.

“…[Display omitted] •New N-4 piperazinyl derivatives of ciprofloxacin.•Cytotoxic activity against different cancer cell lines especially non-small cell lung…”
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Synthesis, molecular docking, antimicrobial evaluation, and DNA cleavage assay of new thiadiazole/oxadiazole ciprofloxacin derivatives by Mohammed, Hamada H. H., Abbas, Samar H., Abdelhafez, El-Shimaa M. N., Berger, James M., Mitarai, Satoshi, Arai, Masayoshi, Abuo-Rahma, Gamal El-Din A. A.

“…Herein we report the synthesis of new N -4-piperazinyl thiadiazole and oxadiazole ciprofloxacin derivatives and their antibacterial and antimycobacterial…”
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Ciprofloxacin Derivative‐Loaded Nanoparticles Synergize with Paclitaxel Against Type II Human Endometrial Cancer by Naguib, Youssef W., Alhaj‐Suliman, Suhaila O., Wafa, Emad I., Saha, Sanjib, Ebeid, Kareem, Mohammed, Hamada H. H., Abdel‐Rahman, Somaya A., Abuo‐Rahma, Gamal El‐Din A., Geary, Sean M., Salem, Aliasger K.

“…Combinations of chemotherapeutic agents comprise a clinically feasible approach to combat cancers that possess resistance to treatment. Type II endometrial…”
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New 1,2,3-triazole linked ciprofloxacin-chalcones induce DNA damage by inhibiting human topoisomerase I& II and tubulin polymerization by Mohammed, Hamada H. H., Abd El-Hafeez, Amer Ali, Ebeid, Kareem, Mekkawy, Aml I., Abourehab, Mohammed A. S., Wafa, Emad I., Alhaj-Suliman, Suhaila O., Salem, Aliasger K., Ghosh, Pradipta, Abuo-Rahma, Gamal El-Din A., Hayallah, Alaa M., Abbas, Samar H.

“…A series of novel 1,2,3-triazole-linked ciprofloxacin-chalcones 4a-j were synthesised as potential anticancer agents. Hybrids 4a-j exhibited remarkable…”
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Novel urea linked ciprofloxacin-chalcone hybrids having antiproliferative topoisomerases I/II inhibitory activities and caspases-mediated apoptosis by Mohammed, Hamada H.H., Abbas, Samar H., Hayallah, Alaa M., Abuo-Rahma, Gamal El-Din A., Mostafa, Yaser A.

“…[Display omitted] •Novel urea linked ciprofloxacin-chalcone hybrids 3a-j.•3c and 3j showed remarkable cytotoxicity against HCT-116 and leukemia-SR…”
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Synthesis and molecular docking of new N4-piperazinyl ciprofloxacin hybrids as antimicrobial DNA gyrase inhibitors by Mohammed, Hamada H. H., Ali, Doaa Mohamed Elroby, Badr, Mohamed, Habib, Ahmed G. K., Mahmoud, Abobakr Mohamed, Farhan, Sarah M., Gany, Shimaa Salah Hassan Abd El, Mohamad, Soad A., Hayallah, Alaa M., Abbas, Samar H., Abuo-Rahma, Gamal El-Din A.

“…A series of N -4 piperazinyl ciprofloxacin derivatives as urea-tethered ciprofloxacin-chalcone hybrids 2a-j and thioacetyl-linked ciprofloxacin-pyrimidine…”
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Synthesis, Physicochemical Characterization using a Facile Validated HPLC Quantitation Analysis Method of 4-Chloro-phenylcarbamoyl-methyl Ciprofloxacin and Its Biological Investigations by Al-Hakkani, Mostafa F, Ahmed, Nourhan, Abbas, Alaa A, Hassan, Mohammad H. A, Aziz, Hossameldin A, Elshamsy, Ali M, Khalifa, Hazim O, Abdelshakour, Mohamed A, Saddik, Mohammed S, Elsayed, Mahmoud M. A, Sabet, Marwa A, El-Mokhtar, Mohamed A, Alsehli, Mosa, Amin, M. S, Abu-Dief, Ahmed M, Mohammed, Hamada H. H

“…A novel derivative of ciprofloxacin (Cpx) was synthesized and characterized using various analytical techniques, including FT-IR spectroscopy, UV-Vis…”
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Design, synthesis and molecular docking of new N-4-piperazinyl ciprofloxacin-triazole hybrids with potential antimicrobial activity by Mohammed, Hamada H.H., Abdelhafez, El-Shimaa M.N., Abbas, Samar H., Moustafa, Gamal A.I., Hauk, Glenn, Berger, James M., Mitarai, Satoshi, Arai, Masayoshi, Abd El-Baky, Rehab M., Abuo-Rahma, Gamal El-Din A.

“…3D Diagrams of compounds 6a interacted with the active site of Mycobacterium gyrase enzyme. [Display omitted] •New ciprofloxacin-triazole…”
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