Search Results - "Mohammed, Aya A. M."
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Fluoroquinolones' Biological Activities against Laboratory Microbes and Cancer Cell Lines
Published in Molecules (Basel, Switzerland) (03-03-2022)“…Development of novel derivatives to rein in and fight bacteria have never been more demanding, as microbial resistance strains are alarmingly increasing. A…”
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Fluoroquinolones structural and medicinal developments (2013–2018): Where are we now?
Published in Bioorganic & medicinal chemistry (15-07-2019)“…[Display omitted] Fluoroquinolones are considered one of the widely utilized antibiotics, specifically, with the recent development of newer generations such…”
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Design, synthesis and antimicrobial evaluation of novel glycosylated-fluoroquinolones derivatives
Published in European journal of medicinal chemistry (15-09-2020)“…Herein we report the design, synthesis and biological evaluation of structurally modified ciprofloxacin, norfloxacin and moxifloxacin standard drugs, featuring…”
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RNA Coronaviruses' Outbreaks: Recent Progress on the SARS-CoV-2 Pandemic Diagnostic Tests, Vaccination and Therapeutics
Published in Mini reviews in medicinal chemistry (01-01-2022)“…Coronaviruses are RNA-infective viruses that could be considered principal players in universal high-profile outbreaks, namely the Severe Acute Respiratory…”
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Design, synthesis, and biological evaluation of 1,8‐naphthyridine glucosamine conjugates as antimicrobial agents
Published in Drug development research (01-02-2019)“…In the quest for discovering potent antimicrobial agents with lower toxicity, we envisioned the design and synthesis of nalidixic acid‐D‐(+)‐glucosamine…”
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Synthesis, urease inhibitory and anticancer evaluation of glucosamine-sulfonylurea conjugates
Published in Medicinal chemistry research (01-04-2024)“…Urease catalyses the hydrolysis of urea to ammonia and carbon dioxide. This enzyme is important in the virulence of several human pathogens and urease activity…”
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