Search Results - "Mohammadhosseini, Mona"

Abstract 531: Disruption of a histone chaperone pathway delays inflammation-driven AML progression by Lin, Hsin-Yun, Mohammadhosseini, Mona, Villamor, Marina, McClatchy, John, Jeng, Sophia, Adey, Andrew, McWeeney, Shannon, Stracker, Travis, Agarwal, Anupriya

“…Abstract Background: Inflammation plays a crucial role in normal and malignant hematopoiesis. Patients with acute myeloid leukemia (AML) exhibit aberrant…”
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3021 – A NOVEL HISTONE CHAPERONE PATHWAY DRIVES IL-1β-MEDIATED AML PROGRESSION by Lin, Hsin-Yun, Mohammadhosseini, Mona, Villamor, Marina, Adey, Andrew, McWeeney, Shannon, Stracker, Travis, Agarwal, Anupriya

“…Genetic heterogeneity remains an ongoing challenge in treating acute myeloid leukemia (AML). Identifying microenvironment-driven pathways that are active…”
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The TLK-ASF1 histone chaperone pathway plays a critical role in IL-1β–mediated AML progression by Lin, Hsin-Yun, Mohammadhosseini, Mona, McClatchy, John, Villamor-Payà, Marina, Jeng, Sophia, Bottomly, Daniel, Tsai, Chia-Feng, Posso, Camilo, Jacobson, Jeremy, Adey, Andrew, Gosline, Sara, Liu, Tao, McWeeney, Shannon, Stracker, Travis H., Agarwal, Anupriya

“…•TLK and ASF1 levels are elevated in patients with AML across genetic subtypes and upregulated by IL-1β–mediated inflammatory stress.•Targeting TLK2 or ASF1B…”
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Investigating effect of ferric stearate on stabilization efficiency of a phenolic antioxidant during thermal oxidation of polyethylene by Mohammadhosseini, Mona, Jahanmardi, Reza

“…This study aimed to achieve a formulation for an additive to produce oxo-biodegradable films that accelerates oxidative degradation of the films after…”
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3093 – CHRONIC IL1Β INDUCED STRESS DRIVES EXPANSION OF TET2 DEFICIENT PROGENITORS THROUGH ENHANCED SELF-RENEWAL ABILITY by McClatchy, John, Strogantsev, Ruslan, Eden, Christopher, Lin, hsin-Yun, Mohammadhosseini, mona, Monteblanco, Andrea, Goldman, Devorah, Cimmino, Luisa, Fleming, William, Mohammed, Hisham, Agarwal, Anupriya

“…Clonal hematopoiesis (CH) increases the risk for the development of myeloid malignancies. Inflammation plays a substantial role in leukemia progression;…”
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Targeting CCL2/CCR2 Signaling Overcomes MEK Inhibitor Resistance in Acute Myeloid Leukemia by Modak, Rucha V, de Oliveira Rebola, Katia G, McClatchy, John, Mohammadhosseini, Mona, Damnernsawad, Alisa, Kurtz, Stephen E, Eide, Christopher A, Wu, Guanming, Laderas, Ted, Nechiporuk, Tamilla, Gritsenko, Marina A, Hansen, Joshua R, Hutchinson, Chelsea, Gosline, Sara J C, Piehowski, Paul, Bottomly, Daniel, Short, Nicholas, Rodland, Karin, McWeeney, Shannon K, Tyner, Jeffrey W, Agarwal, Anupriya

“…Emerging evidence underscores the critical role of extrinsic factors within the microenvironment in protecting leukemia cells from therapeutic interventions,…”
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3024 – GERMLINE RUNX1 MUTATIONS -MEDIATED CHANGES COOPERATES WITH INFLAMMATORY MICROENVIRONMENT TO DRIVE DEFECTIVE HEMATOPOIESIS IN FAMILIAL PLATELET DISORDER by Mohammadhosseini, Mona, Duvall, Adam, Chitsazan, Alex, Enright, Trevor, Monteblanco, Andrea, Lin, Hsin-Yun, Ors, Aysegul, Davis, Brett, Estabrook, Joseph, Nikolova, Olga, Craft, Kathleen, Bresciani, Erica, Merguerian, Matthew, Godley, Lucy, Castilla, Lucio, Demir, Emek, Liu, Paul, Mohammed, Hisham, Agarwal, Anupriya

“…Familial platelet disorder (FPD) is caused by heterozygous germline mutations in RUNX1. FPD individuals have defective platelet functions and increased risk of…”
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Runx1-R188Q germ line mutation induces inflammation and predisposition to hematologic malignancies in mice by Ahmad, Mohd Hafiz, Hegde, Mahesh, Wong, Waihay J, Mohammadhosseini, Mona, Garrett, Lisa, Carrascoso, Anneliese, Issac, Neethu, Ebert, Benjamin, Silva, Jeffrey C, Pihan, German, Zhu, Lihua J, Wolfe, Scot A, Agarwal, Anupriya, Liu, P Paul, Castilla, Lucio H

“…Germ line mutations in the RUNX1 gene cause familial platelet disorder (FPD), an inherited disease associated with lifetime risk to hematopoietic malignancies…”
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