Search Results - "Mohammad, Naushad Shaik"

Tissue-specific DNase I footprint analysis confirms the association of GATAD2B Q470 variant with intellectual disability by Nikam, Vidya, Mohammad, Naushad Shaik

“…Intellectual disability (ID) is a neurodevelopmental disorder in which genetics play a key aetiological role. GATA zinc finger domain-containing 2B ( GATAD2B )…”
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Clinical utility of folate pathway genetic polymorphisms in the diagnosis of autism spectrum disorders by Shaik Mohammad, Naushad, Sai Shruti, P, Bharathi, Venkat, Krishna Prasad, Chintakindi, Hussain, Tajamul, Alrokayan, Salman A, Naik, Usha, Radha Rama Devi, Akella

“…BACKGROUNDThe rationale of the current study was to test the clinical utility of the folate pathway genetic polymorphisms in predicting the risk for autism…”
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Application of machine learning algorithms for the differential diagnosis of peroxisomal disorders by Subhashini, Pammi, Jaya Krishna, Sampangi, Usha Rani, Ganni, Sushma Chander, Nooguri, Maheshwar Reddy, Gummadi, Naushad, Shaik Mohammad

“…Abstract We have established diagnostic thresholds of very long-chain fatty acids (VLCFA) for the differential diagnosis of peroxisomal disorders using the…”
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Adaptive Neuro-Fuzzy Inference System-Based Exploration of the Interrelationships of 25-Hydroxyvitamin D, Calcium, Phosphorus with Parathyroid Hormone Production by Mohan, Iyyapu Krishna, Khan, Siraj Ahmed, Shiva Krishna, D., Vijaya Bhaskar, M., Sai Baba, K. S. S., Hussain, Tajamul, Alrokayan, Salman A., Naushad, Shaik Mohammad

“…The rationale of the current study was to assess the prevalence of 25-hydroxyvitamin D (25-OHD) deficiency and hyperparathyroidism in South Indian population…”
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Pharmacogenetic profiling of dihydropyrimidine dehydrogenase (DPYD) variants in the Indian population by Naushad, Shaik Mohammad, Hussain, Tajamul, Alrokayan, Salman A., Kutala, Vijay Kumar

“…Background The present study aimed to delineate the pharmacologically relevant dihydropyrimidine dehydrogenase (DPYD) variants in the Indian population…”
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Artificial neural network model for predicting the bioavailability of tacrolimus in patients with renal transplantation by Thishya, Kalluri, Vattam, Kiran Kumar, Naushad, Shaik Mohammad, Raju, Shree Bhushan, Kutala, Vijay Kumar

“…The objective of the current study was to explore the role of ABCB1 and CYP3A5 genetic polymorphisms in predicting the bioavailability of tacrolimus and the…”
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A rare case of fatty acyl‐CoA reductase 1 deficiency in an Indian infant manifesting rhizomelic chondrodystrophy phenotype by Radha Rama Devi, Akella, Naushad, Shaik Mohammad, Jain, Romit, Lingappa, Lokesh

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The role of TLR7 agonists in modulating COVID-19 severity in subjects with loss-of-function TLR7 variants by Naushad, Shaik Mohammad, Mandadapu, Gowtham, Ramaiah, Mekala Janaki, Almajhdi, Fahad N., Hussain, Tajamul

“…We investigate the mechanism associated with the severity of COVID-19 in men with TLR7 mutation. Men with loss-of-function (LOF) mutations in TLR7 had severe…”
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Biochemical, machine learning and molecular approaches for the differential diagnosis of Mucopolysaccharidoses by Kadali, Srilatha, Naushad, Shaik Mohammad, Radha Rama Devi, Akella, Bodiga, Vijaya Lakshmi

“…This study was aimed to construct classification and regression tree (CART) model of glycosaminoglycans (GAGs) for the differential diagnosis of…”
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Classification and regression tree-based prediction of 6-mercaptopurine-induced leucopenia grades in children with acute lymphoblastic leukemia by Naushad, Shaik Mohammad, Dorababu, Patchava, Rupasree, Yedluri, Pavani, Addepalli, Raghunadharao, Digumarti, Hussain, Tajamul, Alrokayan, Salman A., Kutala, Vijay Kumar

“…Purpose The rationale of the current study was to develop 6-mercaptopurine (6-MP)-mediated hematological toxicity prediction model for acute lymphoblastic…”
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A pilot study on machine learning approach to delineate metabolic signatures in intellectual disability by Nikam, Vidya, Ranade, Suvidya, Shaik Mohammad, Naushad, Kulkarni, Mohan

“…Intellectual disability (ID) is a neurodevelopmental disorder characterized by cognitive delays. Inborn errors of metabolism constitute an important subgroup…”
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Probing the epigenetic signatures in subjects with coronary artery disease by Indumathi, Bobbala, Oruganti, Sai Satish, Naushad, Shaik Mohammad, Kutala, Vijay Kumar

“…Depletion of S -adenosyl methionine and 5-methyltetrahydrofolate; and elevation of total plasma homocysteine were documented in CAD patients, which might…”
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Machine learning algorithm-based risk prediction model of coronary artery disease by Naushad, Shaik Mohammad, Hussain, Tajamul, Indumathi, Bobbala, Samreen, Khatoon, Alrokayan, Salman A., Kutala, Vijay Kumar

“…In view of high mortality associated with coronary artery disease (CAD), development of an early predicting tool will be beneficial in reducing the burden of…”
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Microarray-based SNP genotyping to identify genetic risk factors of triple-negative breast cancer (TNBC) in South Indian population by Aravind Kumar, M., Singh, Vineeta, Naushad, Shaik Mohammad, Shanker, Uday, Lakshmi Narasu, M.

“…In the view of aggressive nature of Triple-Negative Breast cancer (TNBC) due to the lack of receptors (ER, PR, HER2) and high incidence of drug resistance…”
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Meta-analysis of genetic polymorphisms in xenobiotic metabolizing enzymes and their association with breast cancer risk by Hussain, Tajamul, Alrokayan, Salman, Upasna, Upadhyay, Pavithrakumari, Manickam, Jayapriya, Jaganathan, Kutala, Vijay Kumar, Naushad, Shaik Mohammad

“…Studies on the association of cytochrome p450 A1 (m1, m2), catechol-O-methyltransferase (COMT) H108L, glutathione S -transferase (GST) T1 and M1 polymorphisms…”
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Newborn screening and single nucleotide variation profiling of TSHR, TPO, TG and DUOX2 candidate genes for congenital hypothyroidism by Kollati, Yedukondalu, Akella, Radha Rama Devi, Naushad, Shaik Mohammad, Borkar, Divya, Thalla, Maunika, Nagalingam, Swapna, Lingappa, Lokesh, Patel, Rajesh K., Reddy, G. Bhanuprakash, Dirisala, Vijaya R.

“…High prevalence of congenital hypothyroidism (CH) among Indian newborns prompted us to establish population-specific reference ranges of TSH and to explore the…”
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Artificial neural network-based pharmacogenomic algorithm for warfarin dose optimization by Pavani, Addepalli, Naushad, Shaik Mohammad, Kumar, Rajasekar Manoj, Srinath, Murali, Malempati, Amaresh Rao, Kutala, Vijay Kumar

“…To develop more precise pharmacogenomic algorithm for prediction of safe and effective dose of warfarin. An artificial neural network (ANN) algorithm was…”
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Methodological issues in the development of a pharmacogenomic algorithm for warfarin dosing: comparison of two regression approaches by Pavani, Addepalli, Naushad, Shaik Mohammad, Uma, Addepally, Kutala, Vijay Kumar

“…To ascertain whether multiple polynomial regression (MPR) has any advantage over multiple linear regression (MLR) in developing pharmacogenomic algorithms. Two…”
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Aberrations in one-carbon metabolism induce oxidative DNA damage in sporadic breast cancer by Mohammad, Naushad Shaik, Yedluri, Rupasree, Addepalli, Pavani, Gottumukkala, Suryanarayana Raju, Digumarti, Raghunadha Rao, Kutala, Vijay Kumar

“…The authors investigated the role of dietary micronutrients and eight functional polymorphisms of one-carbon metabolism in modulating oxidative stress in…”
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In silico analysis of the structural and functional implications of SLC19A1 R27H polymorphism by Naushad, Shaik Mohammad, Devi, Akella Radha Rama, Hussain, Tajamul, Alrokayan, Salman A., Ramaiah, M. Janaki, Kutala, Vijay Kumar

“…In view of the documented association of solute carrier family 19 member 1 (SLC19A1) G80A (R27H) polymorphism with the risk for different types of cancers and…”
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