Search Results - "Mohammad, Jiyan"

JNK inhibition blocks piperlongumine-induced cell death and transcriptional activation of heme oxygenase-1 in pancreatic cancer cells by Mohammad, Jiyan, Singh, Rahul R., Riggle, Cody, Haugrud, Brandon, Abdalla, Maher Y., Reindl, Katie M.

“…Piperlongumine (PL) is an alkaloid that inhibits glutathione S -transferase pi 1 (GSTP1) activity, resulting in elevated reactive oxygen species (ROS) levels…”
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Glutathione S-Transferase pi-1 Knockdown Reduces Pancreatic Ductal Adenocarcinoma Growth by Activating Oxidative Stress Response Pathways by Singh, Rahul R., Mohammad, Jiyan, Orr, Megan, Reindl, Katie M.

“…Glutathione S-transferase pi-1 (GSTP1) plays an important role in regulating oxidative stress by conjugating glutathione to electrophiles. GSTP1 is…”
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Abstract A86: Piperlongumine enhances the efficacy of gemcitabine in pancreatic cancer cells in vitro and in vivo by Mohammad, Jiyan, Dhillon, Harsharan, Reindl, Katie

“…Reactive oxygen species (ROS)-inducing agents have been identified as possible treatments for various cancers, including pancreatic cancer. Cancer cells have…”
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Cellulose nanofibers as Scaffold-forming materials for thin film drug delivery systems by Rakib Hasan Khan, Md, Shankar Hazra, Raj, Nair, Gauthami, Mohammad, Jiyan, Jiang, Long, Reindl, Katie, Khalid Jawed, Mohammad, Ganai, Sabha, Quadir, Mohiuddin

“…[Display omitted] We explored the potential of cellulose nanofiber (CNF) for designing prolonged-release, thin-film drug delivery systems (TF-DDS). These…”
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Piperlongumine potentiates the effects of gemcitabine in in vitro and in vivo human pancreatic cancer models by Mohammad, Jiyan, Dhillon, Harsharan, Chikara, Shireen, Mamidi, Sujan, Sreedasyam, Avinash, Chittem, Kishore, Orr, Megan, Wilkinson, John C, Reindl, Katie M

“…Pancreatic ductal adenocarcinoma (PDAC) is one of the deadliest cancers due to a late diagnosis and poor response to available treatments. There is a need to…”
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ZIM, a Norbornene Derived from 4‑Aminoantipyrine, Induces DNA Damage and Cell Death but in Association Reduces the Effect of Commercial Chemotherapeutics by Oliveira, Rodrigo Juliano, da Silveira, Ingridhy Ostaciana Maia Freitas, das Neves, Silvia C., Mitsuyasu, Barbara, Martins, Allana C., Berno, Claudia, Mohammad, Jiyan, Raj, Halie, de Araujo, Flavio H. S., Hortelan, Cristiane Regina, Machado, Luana, da Silva Júnior, Eufrânio N., Vilela, Marcelo L. B., Nascimento, Valter Aragão, Beatriz, Adilson, da Silva Gomes, Roberto

“…Cancer incidence is increasing, and the drugs are not very selective. These drugs cause adverse effects, and the cells become resistant. Therefore, new drugs…”
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Therapeutic Potential of Piperlongumine for Pancreatic Ductal Adenocarcinoma by Mohammad, Jiyan Mageed

“…Pancreatic ductal adenocarcinoma (PDAC) is among the most lethal malignancies because it is often diagnosed at a late disease stage and has a poor response…”
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Design, synthesis and in vivo evaluation of 1,4-dioxo-2-butenyl aryl amine derivatives as a promising anti-inflammatory drug prototype by da Silveira, Ingridhy O.M.F., Moslaves, Iluska S.B., Muller, Jéssica A.I., Hortelan, Cristiane R.W., Juliano Oliveira, Rodrigo, Okuyama, Tatiane T., Fernandes, Juliana, Badenoch, Bretton, Janaína de Campos, Luana, Almeida, Leandro D., Mohammad, Jiyan, Martins, Allana C.F., Beatriz, Adilson, da Silva Júnior, Eufrânio N., Cristina Toffoli-Kadri, Mônica, da Silva Gomes, Roberto

“…[Display omitted] •Virtual screening provided 4 candidates potentially able to strongly inhibit COX isoenzymes in inflammatory process.•Compounds (1–4) reduced…”
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