Search Results - "Mohamedali, A"

Evaluating interior surfaces including finishing materials, ceiling, and their contribution to solar energy in residential buildings in Famagusta, North-Cyprus, Turkey by Farjami, E., Mohamedali, A.

“…With the recent development of sustainable design trend, the major areas to consider are energy resources, construction techniques and materials, water usage…”
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Noninvasive monitoring of orthotopic glioblastoma therapy response using RGD-conjugated iron oxide nanoparticles by Zhang, Fan, Huang, Xinglu, Zhu, Lei, Guo, Ning, Niu, Gang, Swierczewska, Magdalena, Lee, Seulki, Xu, Hong, Wang, Andrew Y, Mohamedali, Khalid A, Rosenblum, Michael G, Lu, Guangming, Chen, Xiaoyuan

“…Abstract Noninvasive imaging techniques have been considered important strategies in the clinic to monitor tumor early response to therapy. In the present…”
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Is isolation of comprehensive human plasma peptidomes an achievable quest? by Mahboob, S., Mohamedali, A., Ahn, S.B., Schulz-Knappe, P., Nice, E., Baker, M.S.

“…The low molecular weight (LMW; <10kDa)* plasma peptidome has been considered a source of useful diagnostic biomarkers and potentially therapeutic molecules, as…”
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High concordance of genomic and cytogenetic aberrations between peripheral blood and bone marrow in myelodysplastic syndrome (MDS) by Mohamedali, A M, Gäken, J, Ahmed, M, Malik, F, Smith, A E, Best, S, Mian, S, Gaymes, T, Ireland, R, Kulasekararaj, A G, Mufti, G J

“…Bone marrow (BM) genetic abnormalities in myelodysplastic syndrome (MDS) have provided important biological and prognostic information; however, frequent BM…”
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Preclinical modeling of myelodysplastic syndromes by Rouault-Pierre, K, Mian, S A, Goulard, M, Abarrategi, A, Di Tulio, A, Smith, A E, Mohamedali, A, Best, S, Nloga, A-M, Kulasekararaj, A G, Ades, L, Chomienne, C, Fenaux, P, Dosquet, C, Mufti, G J, Bonnet, D

“…Myelodysplastic syndromes (MDS) represent a heterogeneous group of hematological clonal disorders. Here, we have tested the bone marrow (BM) cells from 38 MDS…”
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Development of a human immuno-oncology therapeutic agent targeting HER2: targeted delivery of granzyme B by Cheung, Lawrence H, Zhao, Yunli, Alvarez-Cienfuegos, Ana, Mohamedali, Khalid A, Cao, Yu J, Hittelman, Walter N, Rosenblum, Michael G

“…Immunotherapeutic approaches designed to augment T and B cell mediated killing of tumor cells has met with clinical success in recent years suggesting…”
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The TWEAK Receptor Fn14 Is a Therapeutic Target in Melanoma: Immunotoxins Targeting Fn14 Receptor for Malignant Melanoma Treatment by Zhou, Hong, Ekmekcioglu, Suhendan, Marks, John W., Mohamedali, Khalid A., Asrani, Kaushal, Phillips, Keeley K., Brown, Sharron A.N., Cheng, Emily, Weiss, Michele B., Hittelman, Walter N., Tran, Nhan L., Yagita, Hideo, Winkles, Jeffrey A., Rosenblum, Michael G.

“…Fibroblast growth factor-inducible protein 14 (Fn14), the cell surface receptor for tumor necrosis factor-like weak inducer of apoptosis (TWEAK), is…”
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Therapeutic efficacy and safety of a human fusion construct targeting the TWEAK receptor Fn14 and containing a modified granzyme B by Alvarez de Cienfuegos, Ana, Cheung, Lawrence H, Mohamedali, Khalid A, Whitsett, Timothy G, Winkles, Jeffrey A, Hittelman, Walter N, Rosenblum, Michael G

“…Antibody-drug conjugates are an exceptional and useful therapeutic tool for multiple diseases, particularly for cancer treatment. We previously showed that the…”
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Imaging of VEGF Receptor in a Rat Myocardial Infarction Model Using PET by Rodriguez-Porcel, Martin, Cai, Weibo, Gheysens, Olivier, Willmann, Jurgen K, Chen, Kai, Wang, Hui, Chen, Ian Y, He, Lina, Wu, Joseph C, Li, Zi-bo, Mohamedali, Khalid A, Kim, Sehoon, Rosenblum, Michael G, Chen, Xiaoyuan, Gambhir, Sanjiv Sam

“…Myocardial infarction (MI) leads to left ventricular (LV) remodeling, which leads to the activation of growth factors such as vascular endothelial growth…”
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Targeting of Tumor Neovasculature with GrB/VEGF121, a Novel Cytotoxic Fusion Protein by Mohamedali, Khalid A., Rosenblum, Michael G.

“…Angiogenesis is a critical process in numerous diseases, and intervention in neovascularization has therapeutic value in several disease settings, including…”
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The JAK2 V617F mutation identifies a subgroup of MDS patients with isolated deletion 5q and a proliferative bone marrow by Ingram, W, Lea, N C, Cervera, J, Germing, U, Fenaux, P, Cassinat, B, Kiladjian, J J, Varkonyi, J, Antunovic, P, Westwood, N B, Arno, M J, Mohamedali, A, Gaken, J, Kontou, T, Czepulkowski, B H, Twine, N A, Tamaska, J, Csomer, J, Benedek, S, Gattermann, N, Zipperer, E, Giagounidis, A, Garcia-Casado, Z, Sanz, G, Mufti, G J

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The JAK2 V617F mutation is rare in RARS but common in RARS-T by Ceesay, M M, Lea, N C, Ingram, W, Westwood, N B, Gäken, J, Mohamedali, A, Cervera, J, Germing, U, Gattermann, N, Giagounidis, A, Garcia-Casado, Z, Sanz, G, Mufti, G J

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Photochemical internalization augments tumor vascular cytotoxicity and specificity of VEGF121/rGel fusion toxin by Weyergang, Anette, Cheung, Lawrence H., Rosenblum, Michael G., Mohamedali, Khalid A., Peng, Qian, Waltenberger, Johannes, Berg, Kristian

“…Vascular targeting for cancer is increasingly recognized as a therapeutic strategy although the lack of objective responses and the development of resistance…”
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Microsatellite instability induced mutations in DNA repair genes CtIP and MRE11 confer hypersensitivity to poly (ADP-ribose) polymerase inhibitors in myeloid malignancies by Gaymes, Terry J, Mohamedali, Azim M, Patterson, Miranda, Matto, Nazia, Smith, Alexander, Kulasekararaj, Austin, Chelliah, Rajani, Curtin, Nicola, Farzaneh, Farzin, Shall, Sydney, Mufti, Ghulam J

“…Inactivation of the DNA mismatch repair pathway manifests as microsatellite instability, an accumulation of mutations that drives carcinogenesis. Here, we…”
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Inhibition of prostate tumor growth and bone remodeling by the vascular targeting agent VEGF121/rGel by MOHAMEDALI, Khalid A, POBLENZ, Ann T, SIKES, Charles R, NAVONE, Nora M, THORPE, Philip E, DARNAY, Bryant G, ROSENBLUM, Michael G

“…The pathophysiology of tumor growth following skeletal metastases and the poor response of this type of lesion to therapeutic intervention remains incompletely…”
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Cytotoxicity of VEGF121/rGel on vascular endothelial cells resulting in inhibition of angiogenesis is mediated via VEGFR-2 by Mohamedali, Khalid A, Ran, Sophia, Gomez-Manzano, Candelaria, Ramdas, Latha, Xu, Jing, Kim, Sehoon, Cheung, Lawrence H, Hittelman, Walter N, Zhang, Wei, Waltenberger, Johannes, Thorpe, Philip E, Rosenblum, Michael G

“…Abstract Background: The fusion protein VEGF121 /rGel composed of the growth factor VEGF121 and the plant toxin gelonin targets the tumor neovasculature and…”
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PET of Vascular Endothelial Growth Factor Receptor Expression by Cai, Weibo, Chen, Kai, Mohamedali, Khalid A, Cao, Qizhen, Gambhir, Sanjiv S, Rosenblum, Michael G, Chen, Xiaoyuan

“…For solid tumors and metastatic lesions, tumor vascularity is a critical factor in assessing response to therapy. Here we report the first example, to our…”
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Sensitive Angiogenesis Imaging of Orthotopic Bladder Tumors in Mice Using a Selective Magnetic Resonance Imaging Contrast Agent Containing VEGF121/rGel by Cho, Eun-Jin, Yang, Jaemoon, Mohamedali, Khalid A, Lim, Eun-Kyung, Kim, Eun-Jung, Farhangfar, Carol J, Suh, Jin-Suck, Haam, Seungjoo, Rosenblum, Michael G, Huh, Yong-Min

“…OBJECTIVES:To investigate the efficiency of magnetic resonance imaging (MRI) contrast agents employing vascular endothelial growth factor (VEGF121)/rGel…”
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Characterization and Mechanistic Studies of a Novel Melanoma-Targeting Construct Containing IκBa for Specific Inhibition of Nuclear Factor-κB Activity by Zhou, Hong, Liu, Yuying, Cheung, Lawrence H., Kim, Sehoon, Zhang, Weihe, Mohamedali, Khalid A., Anand, Preetha, Hittelman, Walter N., Aggarwal, Bharat B., Rosenblum, Michael G.

“…The transcription factor nuclear factor-κB (NF-κB) is a central mediator of growth and homeostasis for both normal and neoplastic cells. IκBα is the natural…”
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Multiplexed PET Probes for Imaging Breast Cancer Early Response to VEGF121/rGel Treatment by Yang, Min, Gao, Haokao, Sun, Xilin, Yan, Yongjun, Quan, Qimeng, Zhang, Wendy, A. Mohamedali, Khalid, Rosenblum, Michael G, Niu, Gang, Chen, Xiaoyuan

“…In this study, we applied multiplexed positron emission tomography (PET) probes to monitor glucose metabolism, cellular proliferation, tumor hypoxia and…”
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