Search Results - "Mohamed Elsayed"

Indenoisoquinoline Topoisomerase Inhibitors Strongly Bind and Stabilize the MYC Promoter G‑Quadruplex and Downregulate MYC by Wang, Kai-Bo, Elsayed, Mohamed S. A, Wu, Guanhui, Deng, Nanjie, Cushman, Mark, Yang, Danzhou

“…MYC is one of the most important oncogenes and is overexpressed in the majority of cancers. G-Quadruplexes are noncanonical four-stranded DNA secondary…”
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Mental health, risk perception, and coping strategies among healthcare workers in Egypt during the COVID-19 pandemic by Elsayed, Mohamed E G, El-Abasiri, Radwa Abdullah, Marzo, Roy Rillera, Dardeer, Khaled T, Kamal, Manar Ahmed, Abdelaziz, Heba, Soliman, Soliman Belal, Htay, Mila Nu Nu

“…Coronavirus disease-19 emerged in December 2019. Healthcare workers were exposed to this highly infectious virus during the pandemic and suffered several…”
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Synthesis of Benzo[1,6]naphthyridinones Using the Catellani Reaction by Elsayed, Mohamed S. A, Griggs, Brittany, Cushman, Mark

“…An intramolecular version of the Catellani reaction was optimized for one-step synthesis of bulky N-substituted benzo­[1,6]­naphthyridinones with good to…”
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Modelling net irrigation water requirements using FAO-CROPWAT 8.0 and CLIMWAT 2.0: a case study of Tina Plain and East South ElKantara regions, North Sinai, Egypt by Gabr, Mohamed ELSayed

“…The present study aims at estimating net and gross water requirements of eight major irrigated crops in the agro-ecological regions Tina Plain (AER 1), and…”
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Organization of Endothelial Cells, Pericytes, and Astrocytes into a 3D Microfluidic in Vitro Model of the Blood–Brain Barrier by Wang, Jack D, Khafagy, El-Sayed, Khanafer, Khalil, Takayama, Shuichi, ElSayed, Mohamed E. H

“…The endothelial cells lining the capillaries supplying the brain with oxygen and nutrients form a formidable barrier known as the blood–brain barrier (BBB),…”
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Exergoeconomic analysis and optimization of an integrated system of supercritical CO2 Brayton cycle and multi-effect desalination by Alharbi, Sattam, Elsayed, Mohamed L., Chow, Louis C.

“…A cogeneration system is proposed for power and fresh water production in which the waste heat from a supercritical CO2 recompression Brayton cycle is utilized…”
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Novel Fluoroindenoisoquinoline Non-Camptothecin Topoisomerase I Inhibitors by Marzi, Laetitia, Agama, Keli, Murai, Junko, Difilippantonio, Simone, James, Amy, Peer, Cody J, Figg, William D, Beck, Daniel, Elsayed, Mohamed S A, Cushman, Mark, Pommier, Yves

“…Contrary to other anticancer targets, topoisomerase I (TOP1) is targeted by only one chemical class of FDA-approved drugs: topotecan and irinotecan, the…”
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Adaptive laboratory evolution of Rhodosporidium toruloides to inhibitors derived from lignocellulosic biomass and genetic variations behind evolution by Liu, Zhijia, Radi, Mohammad, Mohamed, Elsayed T.T., Feist, Adam M., Dragone, Giuliano, Mussatto, Solange I.

“…•A strategy of adaptive laboratory evolution in hydrolysate-based medium was developed.•Evolved strains of Rhodosporidium toruloides presented better tolerance…”
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Land reclamation projects in the Egyptian Western Desert: management of 1.5 million acres of groundwater irrigation by Gabr, Mohamed Elsayed

“…This study examines the primary issues that Egypt's irrigated agriculture faces in the land reclamation project in the Western Desert and potential solutions…”
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Dendrimer-doxorubicin conjugates exhibit improved anticancer activity and reduce doxorubicin-induced cardiotoxicity in a murine hepatocellular carcinoma model by Kuruvilla, Sibu P, Tiruchinapally, Gopinath, Crouch, A Colleen, ElSayed, Mohamed E H, Greve, Joan M

“…Hepatocellular carcinoma (HCC) is the 2nd leading cause of cancer-related deaths every year globally. The most common form of treatment, hepatic arterial…”
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Design methodology for sewage water treatment system comprised of Imhoff 's tank and a subsurface horizontal flow constructed wetland: a case study Dakhla Oasis, Egypt by Gabr, Mohamed Elsayed

“…In this study, in order to reuse the treated wastewater in irrigation in rural areas, a new sewage water treatment system comprised of primary treatment…”
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Recent advances in proteolytic stability for peptide, protein, and antibody drug discovery by Lai, Xianyin, Tang, Jason, ElSayed, Mohamed E H

“…: To discover and develop a peptide, protein, or antibody into a drug requires overcoming multiple challenges to obtain desired properties. Proteolytic…”
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Characterization and impact of peptide physicochemical properties on oral and subcutaneous delivery by Klepach, Alisa, Tran, Huyen, Ahmad Mohammed, Faiz, ElSayed, Mohamed E.H.

“…[Display omitted] Peptides, an emerging modality within the biopharmaceutical industry, are often delivered subcutaneously with evolving prospects on oral…”
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Exergy and thermo-economic analysis for MED-TVC desalination systems by Elsayed, Mohamed L., Mesalhy, Osama, Mohammed, Ramy H., Chow, Louis C.

“…An exergo-economic model is used to simulate four different feed configurations of multi-effect desalination with thermal vapor compressor (MED-TVC) system…”
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Progress and limitations of oral peptide delivery as a potentially transformative therapy by Tran, Huyen, ElSayed, Mohamed E H

“…Numerous formulation technologies have been developed to overcome challenges of oral peptide delivery. Understanding the advantages and limitations of each…”
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Impact of climatic changes on future irrigation water requirement in the Middle East and North Africa's region: a case study of upper Egypt by Gabr, Mohamed Elsayed

“…Freshwater shortages in the Middle East and North Africa's region (MENA) cause serious issues, while climate change causes even more issues. The current study…”
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Hexagon path planning algorithm by Arnaoot, Hany Mohamed Elsayed Ibrahim Mohamed

“…The paper presents a novel 2D geometrical path plan algorithm that reduces calculation load and time by filtering obstacles before path planning starts by the…”
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Identification of a Multi-Component Formulation for Intestinal Delivery of a GLP-1/Glucagon Co-agonist Peptide by Tran, Huyen, Patel, Phenil J., Aburub, Aktham, Sperry, Andrea, Estwick, Selina, ElSayed, Mohamed E. H., –Mannan, Amita Datta

“…Purpose Oral delivery of therapeutic peptides has been challenging due to multiple physiological factors and physicochemical properties of peptides. We report…”
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Bottom-Up Fabrication of Multilayer Enteric Devices for the Oral Delivery of Peptides by Nemeth, Cameron L., Lykins, William R., Tran, Huyen, ElSayed, Mohamed E. H., Desai, Tejal A.

“…Purpose To develop a planar, asymmetric, micro-scale oral drug delivery vehicle by i) fabricating microdevice bodies with enteric materials, ii) efficiently…”
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Resistance patterns, virulence determinants, and biofilm genes of multidrug-resistant Pseudomonas aeruginosa isolated from fish and fish handlers by Abou Elez, Rasha M. M., Zahra, Eman Mohamed Fayek, Gharieb, Rasha M. A., Mohamed, Mohamed Elsayed Mohamed, Samir, Mohamed, Saad, Alaaeldin Mohamed, Merwad, Abdallah Mohamed Amin

“…Pseudomonas aeruginosa ( P. aeruginosa ) is an opportunistic bacterium that is widely distributed in aquatic environments and causes major economic losses in…”
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