Search Results - "Mohamed, Nabil Z"

Aspergillus Niger thermostable Cytosine deaminase-dextran conjugates with enhanced structure stability, proteolytic resistance, and Antiproliferative activity by El-Sayed, Ashraf S A, Rady, Amgad M, Mohamed, Hossam Taha, Zein, Nabila, Yassin, Marwa A, Mohamed, Nabil Z, Hassan, Abdallah, Amer, Mahmoud M, El-Sharakawy, Reyad, El-Sharkawy, Aya Ali, El-Sayed, Nesma, Ali, Mostafa G

“…Cytosine deaminase (CDA) is a prodrug mediating enzyme converting 5-flurocytosine into 5-flurouracil with profound broad-range anticancer activity towards…”
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Phytochemical and metabolic profiling of the different Podocarpus species in Egypt: Potential antimicrobial and antiproliferative activities by Mohamed, Nabil Z., Shaaban, Lamis, Safan, Samia, El-Sayed, Ashraf S.A.

“…Podocarpus is the most dominant genus of Podocarpaceae, with higher taxonomical proximity to the Taxaceae, having numerous pharmaceutical applications,…”
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Microbial cytosine deaminase is a programmable anticancer prodrug mediating enzyme: antibody, and gene directed enzyme prodrug therapy by El-Sayed, Ashraf S.A., Mohamed, Nabil Z., Yassin, Marwa A., Amer, Mahmoud M., El-Sharkawy, Reyad, El-Sayed, Nesma, Ali, Mostafa G.

“…Cytosine deaminase (CDA) is a non-mammalian enzyme with powerful activity in mediating the prodrug 5-fluorcytosine (5-FC) into toxic drug 5-fluorouracil…”
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Induction of Taxol biosynthesis by Aspergillus terreus, endophyte of Podocarpus gracilior Pilger, upon intimate interaction with the plant endogenous microbes by El-Sayed, Ashraf S.A., Safan, Samia, Mohamed, Nabil Z., Shaban, Lamis, Ali, Gul Shad, Sitohy, Mahmoud Z.

“…[Display omitted] •A. terreus endophytes of P. gracilior were reported as potent Taxol producers.•A. terreus Taxol had a strong activity against HEPG2 and MCF7…”
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Physiological and metabolic traits of Taxol biosynthesis of endophytic fungi inhabiting plants: Plant-microbial crosstalk, and epigenetic regulators by Mohamed, Nabil Z., Shaban, Lamis, Safan, Samia, El-Sayed, Ashraf S.A.

“…Attenuating the Taxol productivity of fungi with the subculturing and storage under axenic conditions is the challenge that halts the feasibility of fungi to…”
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Restoring the Taxol biosynthetic machinery of Aspergillus terreus by Podocarpus gracilior Pilger microbiome, with retrieving the ribosome biogenesis proteins of WD40 superfamily by El-Sayed, Ashraf S. A., Mohamed, Nabil Z., Safan, Samia, Yassin, Marwa A., Shaban, Lamis, Shindia, Ahmed A., Shad Ali, Gul, Sitohy, Mahmoud Z.

“…Attenuating the Taxol yield of Aspergillus terreus with the subculturing and storage were the technical challenges that prevent this fungus to be a novel…”
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