Search Results - "Mohamed, Hiba S"
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EBV Associated Breast Cancer Whole Methylome Analysis Reveals Viral and Developmental Enriched Pathways
Published in Frontiers in oncology (13-08-2018)“…Breast cancer (BC) ranks among the most common cancers in Sudan and worldwide with hefty toll on female health and human resources. Recent studies have…”
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HIF-1 regulates heritable variation and allele expression phenotypes of the macrophage immune response gene SLC11A1 from a Z-DNA–forming microsatellite
Published in Blood (15-10-2007)“…The Ity/Lsh/Bcg locus encodes the macrophage protein Slc11a1/Nramp1, which protects inbred mice against infection by diverse intracellular pathogens including…”
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The Association of High Prevalence of Trophozoites in Peripheral Blood with Lower Antibody Response to P. falciparum Infected Erythrocytes among Asymptomatic Children in Sudan
Published in Mediators of inflammation (01-01-2016)“…Background. The most prominent variant surface antigens (VSAs) of Plasmodium falciparum are the var gene-encoded Plasmodium falciparum erythrocyte membrane…”
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Y chromosome lineage- and village-specific genes on chromosomes 1p22 and 6q27 control visceral leishmaniasis in Sudan
Published in PLoS genetics (01-05-2007)“…Familial clustering and ethnic differences suggest that visceral leishmaniasis caused by Leishmania donovani is under genetic control. A recent genome scan…”
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Exome sequencing of a colorectal cancer family reveals shared mutation pattern and predisposition circuitry along tumor pathways
Published in Frontiers in genetics (15-09-2015)“…The molecular basis of cancer and cancer multiple phenotypes are not yet fully understood. Next Generation Sequencing promises new insight into the role of…”
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Candidate malaria susceptibility/protective SNPs in hospital and population-based studies: the effect of sub-structuring
Published in Malaria journal (08-05-2010)“…Populations of East Africa including Sudan, exhibit some of the highest indices of genetic diversity in the continent and worldwide. The current study aims to…”
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Transmission of Plasmodium vivax in Duffy-negative individuals in central Sudan
Published in Transactions of the Royal Society of Tropical Medicine and Hygiene (01-04-2016)“…Background Due to the recently observed rise in Plasmodium vivax incidence in Sudan and reported transmission in Duffy-negative individuals; we aimed to assess…”
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Epstein Barr virus: a prime candidate of breast cancer aetiology in Sudanese patients
Published in Infectious agents and cancer (07-03-2014)“…Breast cancer is the commonest cancer in Sudanese women. Reported genetic alterations in the form of mutations in tumor suppressors are low in frequencies and…”
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Insights into the possible role of IFNG and IFNGR1 in Kala-azar and Post Kala-azar Dermal Leishmaniasis in Sudanese patients
Published in BMC infectious diseases (03-12-2014)“…Little is known about the parasite/host factors that lead to Post Kala-azar Dermal Leishmaniasis (PKDL) in some visceral leishmaniasis (VL) patients after…”
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Genetic and Functional Evidence Implicating "DLL1" as the Gene That Influences Susceptibility to Visceral Leishmaniasis at Chromosome 6q27
Published in The Journal of infectious diseases (01-08-2011)“…Background. Visceral leishmaniasis (VL) is caused by Leishmania donovani and Leishmania infantum chagasi. Genome-wide linkage studies from Sudan and Brazil…”
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Candidate gene analysis supports a role for polymorphisms at TCF7L2 as risk factors for type 2 diabetes in Sudan
Published in Journal of diabetes and metabolic disorders (01-03-2016)“…Background Genetic susceptibility to type 2 diabetes (T2D) is multifactorial. A growing number of genes have been identified as risk factors for T2D across…”
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Distribution of erythrocyte binding antigen 175 (EBA-175) gene dimorphic alleles in Plasmodium falciparum field isolates from Sudan
Published in BMC infectious diseases (09-10-2013)“…The Erythrocyte Binding Antigen (EBA) 175 has been considered as one of the most important Plasmodium falciparum (P. falciparum) merozoite ligands that mediate…”
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Genetics and visceral leishmaniasis in the Sudan: seeking a link
Published in Trends in parasitology (01-06-2004)“…With the human genome sequence in hand, emphasis is now focusing on genetic diversity and its role in susceptibility to disease. In the Sudan, different tribes…”
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Distribution of erythrocyte binding antigen 175 (EBA-175) gene dimorphic alleles in Plasmodium falciparumfield isolates from Sudan
Published in BMC infectious diseases (09-10-2013)“…The Erythrocyte Binding Antigen (EBA) 175 has been considered as one of the most important Plasmodium falciparum (P. falciparum) merozoite ligands that mediate…”
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IFNG and IFNGR1 gene polymorphisms and susceptibility to post-kala-azar dermal leishmaniasis in Sudan
Published in Genes and immunity (01-01-2007)“…Post-kala-azar dermal leishmanaisis (PKDL) in Sudan is associated with elevated interferon-gamma (IFN-gamma). To study interferon-gamma pathways in PKDL, we…”
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Y Chromosome Lineage- and Village-Specific Genes on Chromosomes 1p22 and 6q27 Control Visceral Leishmaniasis in The Sudan
Published in PLoS genetics (2005)Get full text
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