Search Results - "Mohajerani, H."
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Noise exposure accelerates the risk of cognitive impairment and Alzheimer’s disease: Adulthood, gestational, and prenatal mechanistic evidence from animal studies
Published in Neuroscience and biobehavioral reviews (01-10-2020)“…•Chronic noise exposure dysregulates the neuroendocrine system leading to hyperactivity of the hypothalamic-pituitary-adrenal (HPA)-axis.•Stress hormones…”
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Chronic traffic noise stress accelerates brain impairment and cognitive decline in mice
Published in Experimental neurology (01-10-2018)“…Although traffic noise exposure is a well-known environmental pollutant whose negative health effect has been discussed in different aspects of the human life,…”
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Hippocampus-dependent emergence of spatial sequence coding in retrosplenial cortex
Published in Proceedings of the National Academy of Sciences - PNAS (31-07-2018)“…Retrosplenial cortex (RSC) is involved in visuospatial integration and spatial learning, and RSC neurons exhibit discrete, place cell-like sequential activity…”
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Spontaneous cortical activity alternates between motifs defined by regional axonal projections
Published in Nature neuroscience (01-10-2013)“…Using voltage sensitive–dye imaging in the cortices of anesthetized and awake mice, the authors show that spontaneous activity patterns contain similar motifs…”
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Age-dependent behavioral and biochemical characterization of single APP knock-in mouse (APPNL-G-F/NL-G-F) model of Alzheimer's disease
Published in Neurobiology of aging (01-03-2019)“…Saito et al developed a novel amyloid precursor protein (APP) knock-in mouse model (APPNL-G-F) for Alzheimer's disease (AD) to overcome the problem of…”
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Prenatal noise stress impairs HPA axis and cognitive performance in mice
Published in Scientific reports (05-09-2017)“…Noise stress is a common environmental pollutant whose adverse effect on offspring performance has been less studied. This study was novel in terms of using…”
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Low-cost solution for rodent home-cage behaviour monitoring
Published in PloS one (02-08-2019)“…In the current research on measuring complex behaviours/phenotyping in rodents, most of the experimental design requires the experimenter to remove the animal…”
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Spatiotemporal patterns of neocortical activity around hippocampal sharp-wave ripples
Published in eLife (13-03-2020)“…A prevalent model is that sharp-wave ripples (SWR) arise 'spontaneously' in CA3 and propagate recent memory traces outward to the neocortex to facilitate…”
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Prepulse inhibition of the acoustic startle reflex and P50 gating in aging and alzheimer’s disease
Published in Ageing research reviews (01-05-2020)“…•Aging is associated with functional impairments in inhibitory mechanisms.•Age-related alterations of prepulse inhibition (PPI) are further compromised in…”
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Spatial Information Encoding across Multiple Neocortical Regions Depends on an Intact Hippocampus
Published in The Journal of neuroscience (13-01-2021)“…There has been considerable research showing populations of neurons encoding for different aspects of space in the brain. Recently, several studies using…”
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Miniaturized head-mounted microscope for whole-cortex mesoscale imaging in freely behaving mice
Published in Nature methods (01-04-2021)“…The advent of genetically encoded calcium indicators, along with surgical preparations such as thinned skulls or refractive-index-matched skulls, has enabled…”
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Mirrored Bilateral Slow-Wave Cortical Activity within Local Circuits Revealed by Fast Bihemispheric Voltage-Sensitive Dye Imaging in Anesthetized and Awake Mice
Published in The Journal of neuroscience (10-03-2010)“…Spontaneous slow-wave oscillations of neuronal membrane potential occur about once every second in the rodent cortex and may serve to shape the efficacy of…”
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13
Targeted mini-strokes produce changes in interhemispheric sensory signal processing that are indicative of disinhibition within minutes
Published in Proceedings of the National Academy of Sciences - PNAS (31-05-2011)“…Most processing of sensation involves the cortical hemisphere opposite (contralateral) to the stimulated limb. Stroke patients can exhibit changes in the…”
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Optogenetic mapping after stroke reveals network-wide scaling of functional connections and heterogeneous recovery of the peri-infarct
Published in The Journal of neuroscience (03-12-2014)“…We used arbitrary point channelrhodopsin-2 (ChR2) stimulation and wide-scale voltage sensitive dye (VSD) imaging in mice to map altered cortical connectivity…”
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Polyglactin 910 suture compared with polyglactin 910 coated with triclosan in dental implant surgery: randomized clinical trial
Published in International journal of oral and maxillofacial surgery (01-10-2019)“…Antibacterial coating of surgical sutures is a suggested approach to prevent surgical site infections. The aim of this study was to compare the incidence of…”
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Regional variation in cholinergic terminal activity determines the non-uniform occurrence of cortical slow waves during REM sleep in mice
Published in Cell reports (Cambridge) (30-05-2023)“…Sleep consists of two basic stages: non-rapid eye movement (NREM) and rapid eye movement (REM) sleep. NREM sleep is characterized by slow high-amplitude…”
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Cortical reactivation of spatial and non-spatial features coordinates with hippocampus to form a memory dialogue
Published in Nature communications (27-11-2023)“…Episodic memories comprise diverse attributes of experience distributed across neocortical areas. The hippocampus is integral to rapidly binding these diffuse…”
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Corticosterone response to gestational stress and postpartum memory function in mice
Published in PloS one (10-07-2017)“…Maternal stress is a common adversity during pregnancy. Gestational corticosterone alternations are thought to contribute to the etiology of postpartum…”
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Does the serum level of vitamin D affect marginal bone loss around dental implants?
Published in International journal of oral and maxillofacial surgery (01-06-2022)“…Vitamin D is effective in bone healing. The aim of this study was to assess marginal bone loss (MBL) around dental implants in patients with sufficient and…”
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Altered cortical processing of sensory input in Huntington disease mouse models
Published in Neurobiology of disease (01-07-2022)“…Huntington disease (HD), a hereditary neurodegenerative disorder, manifests as progressively impaired movement and cognition. Although early abnormalities of…”
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