Search Results - "Mogire, Reagan M"
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Prevalence of vitamin D deficiency in Africa: a systematic review and meta-analysis
Published in The Lancet global health (01-01-2020)“…Vitamin D deficiency is associated with non-communicable and infectious diseases, but the vitamin D status of African populations is not well characterised. We…”
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Hepcidin regulation in Kenyan children with severe malaria and non-typhoidal Salmonella bacteremia
Published in Haematologica (Roma) (01-07-2022)“…Malaria and invasive non-typhoidal Salmonella (NTS) are life-threatening infections that often co-exist in African children. The iron-regulatory hormone…”
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Prevalence and predictors of vitamin D deficiency in young African children
Published in BMC medicine (20-05-2021)“…Children living in sub-Saharan Africa have a high burden of rickets and infectious diseases, conditions that are linked to vitamin D deficiency. However, data…”
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Vitamin D Deficiency and Its Association with Iron Deficiency in African Children
Published in Nutrients (25-03-2022)“…Vitamin D regulates the master iron hormone hepcidin, and iron in turn alters vitamin D metabolism. Although vitamin D and iron deficiency are highly prevalent…”
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Target-similarity search using Plasmodium falciparum proteome identifies approved drugs with anti-malarial activity and their possible targets
Published in PloS one (31-10-2017)“…Malaria causes about half a million deaths annually, with Plasmodium falciparum being responsible for 90% of all the cases. Recent reports on artemisinin…”
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Protein target similarity is positive predictor of in vitro antipathogenic activity: a drug repurposing strategy for Plasmodium falciparum
Published in Journal of cheminformatics (30-05-2024)“…Drug discovery is an intricate and costly process. Repurposing existing drugs and active compounds offers a viable pathway to develop new therapies for various…”
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The Multistage Antimalarial Compound Calxinin Perturbates P. falciparum Ca2+ Homeostasis by Targeting a Unique Ion Channel
Published in Pharmaceutics (28-06-2022)“…Malaria elimination urgently needs novel antimalarial therapies that transcend resistance, toxicity, and high costs. Our multicentric international…”
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Ex vivo and In vitro antiplasmodial activities of approved drugs predicted to have antimalarial activities using chemogenomics and drug repositioning approach
Published in Heliyon (01-08-2023)“…High malaria mortality coupled with increased emergence of resistant multi-drug resistant strains of Plasmodium parasite, warrants the development of new and…”
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Effects of vitamin D deficiency on neurobehavioural outcomes in children: a systematic review
Published in Wellcome open research (11-06-2020)“…Introduction: Vitamin D plays an important role in brain development in experimental studies; however, the effect of vitamin D deficiency on child development…”
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Challenges in estimating the prevalence of vitamin D deficiency in Africa – Authors' reply
Published in The Lancet global health (01-04-2022)Get full text
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Challenges in estimating the prevalence of vitamin D deficiency in Africa
Published in The Lancet global health (01-04-2022)Get full text
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12
Iron Deficiency Is Associated With Reduced Levels of Plasmodium falciparum-specific Antibodies in African Children
Published in Clinical infectious diseases (01-07-2021)“…Iron deficiency (ID) and malaria are common causes of ill-health and disability among children living in sub-Saharan Africa. Although iron is critical for the…”
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13
Effects of vitamin D deficiency on neurobehavioural outcomes in children: a systematic review
Published in Wellcome open research (2020)“…Vitamin D plays an important role in brain development in experimental studies; however, the effect of vitamin D deficiency on child development remains…”
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Journal Article -
14
The Multistage Antimalarial Compound Calxinin Perturbates P. falciparum Ca 2+ Homeostasis by Targeting a Unique Ion Channel
Published in Pharmaceutics (28-06-2022)“…Malaria elimination urgently needs novel antimalarial therapies that transcend resistance, toxicity, and high costs. Our multicentric international…”
Get full text
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