Search Results - "Mogil, Lauren S."
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Genetic architecture of gene expression traits across diverse populations
Published in PLoS genetics (10-08-2018)“…For many complex traits, gene regulation is likely to play a crucial mechanistic role. How the genetic architectures of complex traits vary between populations…”
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Identification of Differential Tumor Subtypes of T1 Bladder Cancer
Published in European urology (01-10-2020)“…Stage T1 bladder cancers have the highest progression and recurrence rates of all non–muscle-invasive bladder cancers (NMIBCs). Most T1 cancers are treated…”
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Genetically regulated gene expression underlies lipid traits in Hispanic cohorts
Published in PloS one (08-08-2019)“…Plasma lipid levels are risk factors for cardiovascular disease, a leading cause of death worldwide. While many studies have been conducted in genetic…”
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Supercoiling Effects on Short-Range DNA Looping in E. coli
Published in PloS one (26-10-2016)“…DNA-protein loops can be essential for gene regulation. The Escherichia coli lactose (lac) operon is controlled by DNA-protein loops that have been studied for…”
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Gene-based association study for lipid traits in diverse cohorts implicates BACE1 and SIDT2 regulation in triglyceride levels
Published in PeerJ (San Francisco, CA) (29-01-2018)“…Plasma lipid levels are risk factors for cardiovascular disease, a leading cause of death worldwide. While many studies have been conducted on lipid genetics,…”
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Mechanical Properties of Base-Modified DNA Are Not Strictly Determined by Base Stacking or Electrostatic Interactions
Published in Biophysical journal (15-07-2014)“…This work probes the mystery of what balance of forces creates the extraordinary mechanical stiffness of DNA to bending and twisting. Here we explore the…”
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Multiethnic meta-analysis identifies ancestry-specific and cross-ancestry loci for pulmonary function
Published in Nature communications (30-07-2018)“…Nearly 100 loci have been identified for pulmonary function, almost exclusively in studies of European ancestry populations. We extend previous research by…”
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Corrigendum to “Identification of Differential Tumor Subtypes of T1 Bladder Cancer” [Eur. Urol. 78 (2020) 533–537]
Published in European urology (01-02-2022)Get full text
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Computational and experimental analyses of retrotransposon-associated minisatellite DNAs in the soybean genome
Published in BMC bioinformatics (13-03-2012)“…Retrotransposons are mobile DNA elements that spread through genomes via the action of element-encoded reverse transcriptases. They are ubiquitous constituents…”
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A shotgun approach to discovering and reconstructing consensus retrotransposons ex novo from dense contigs of short sequences derived from Genbank Genome Survey Sequence database records
Published in Gene (15-12-2009)“…Retrotransposons constitute the majority of pseudogenic protein coding regions of most eukaryotic genomes. Most genomes carry tens to thousands of…”
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The Effects of Base Stacking on DNA Flexibility
Published in Biophysical journal (28-01-2014)Get full text
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Evaluation and Analysis of DNA supercoiling and Protein Mediated DNA Loops in vivo and in vitro
Published 01-01-2016“…DNA supercoiling plays a critical role in cellular function. Both prokaryotes and eukaryotes contain negatively supercoiled DNA. DNA supercoiling is required…”
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Dissertation