Search Results - "Moghe, P.V."

Rare-earth-doped biological composites as in vivo shortwave infrared reporters by Naczynski, D. J., Tan, M. C., Zevon, M., Wall, B., Kohl, J., Kulesa, A., Chen, S., Roth, C. M., Riman, R. E., Moghe, P. V.

“…The extension of in vivo optical imaging for disease screening and image-guided surgical interventions requires brightly emitting, tissue-specific materials…”
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Analysis of Surface Microtopography of Biodegradable Polymer Matrices Using Confocal Reflection Microscopy by Semler, Eric J., Tjia, Jane S., Moghe, Prabhas V.

“…Currently, synthetic degradable polymers are frequently employed as culture substrates prior to cell transplantation and as implantable scaffolds for cellular…”
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Engineering hepatocellular morphogenesis and function via ligand-presenting hydrogels with graded mechanical compliance by Semler, Eric J., Lancin, Perry A., Dasgupta, Anouska, Moghe, Prabhas V.

“…In order to evaluate the sensitivity of hepatocellular cultures to variations in both substrate stiffness and bioactive ligand presentation, hepatocytes were…”
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Nanolipoblockers: nanoscale assemblies for potential treatment of atherosclerosis by Moghe, P.V.

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Mechanochemical manipulation of hepatocyte aggregation can selectively induce or repress liver-specific function by Semler, Eric J., Ranucci, Colette S., Moghe, Prabhas V.

“…Controlled activation of hepatocyte aggregation is critical to three‐dimensional (3D) multicellular morphogenesis during native regeneration of liver as well…”
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Advanced Materials: Kinetically Assembled Nanoparticles of Bioactive Macromolecules Exhibit Enhanced Stability and Cell Targeted Biological Efficacy by York, A.W, Zablocki, K.R, Lewis, D.R, Li, Gu, Uhrich, K.E, Prudhomme, R.K, Moghe, P.V

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Functional engineering of hepatocytes via heterocellular presentation of a homoadhesive molecule, E-cadherin by Brieva, Thomas A., Moghe, Prabhas V.

“…Engineering functional activity of liver cell cultures requires the modulation of specific cell–cell interactions. We have investigated the quantitative role…”
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Exogenous cadherin microdisplay can interfere with endogenous signaling and reprogram gene expression in cultured hepatocytes by Brieva, Thomas A., Moghe, Prabhas V.

“…We recently found that the basal micro substrate presentation of E‐cadherin, a key cell–cell adhesion molecule in the liver, can modulate hepatocellular…”
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Engineering hepatocyte functional fate through growth factor dynamics: The role of cell morphologic priming by Semler, Eric J., Moghe, Prabhas V.

“…We have reported previously that cellular stimulation induced by variable mechanochemical properties of the extracellular microenvironment can significantly…”
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Cell-cell interactions are essential for maintenance of hepatocyte function in collagen gel but not on matrigel by Moghe, Prabhas V., Coger, Robin N., Toner, Mehmet, Yarmush, Martin L.

“…The objective of this study was to examine the importance of cellular aggregation for the maintenance of liver‐specific functions in hepatocytes. We used two…”
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Nanoscale engineering of LDL-retentive substrates by Chnari, E., Moghe, P.V.

“…Atherosclerosis, the hardening of arteries due to build-up of lipoproteins, is one of the leading causes of death in the United States. Conventional therapies…”
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Hepatocellular engineering via acellular cadherin-derived microinterfaces by Brieva, T.A., Moghe, P.V.

“…The development of cell-based therapies for liver failure relies on the availability of scaffolds that support high levels of cellular function. In this work,…”
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Engineering cell motility via substrate incorporation of poly(ethylene glycol) by Sharma, R.I., Kohn, J., Moghe, P.V.

“…This study examined the modulation of cell migratory responsiveness to protein-adsorbed poly(ethylene glycol) (PEG) variant copolymers. To this end,…”
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Selective regulation of protein bioactivity and cell adhesion and migration via PEG microdomains on biopolymers by Tziampazis, E., Cassaday, J.A., Kohn, J., Moghe, P.V.

“…It is well established that biomaterial surface chemistry plays a key role in modulating cell and tissue integration on polymeric implants. A commonly used…”
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Induction of cell migration on synthetic polymer substrates through tailored cell-substrate matrix reciprocity by Tjia, J.S., Aneskievich, B.J., Moghe, P.V.

“…Limited epithelial cell migration on synthetic polymeric biomaterials, such as polyesters, presents a serious challenge to their use as scaffolds for…”
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