Search Results - "Moghe, Gaurav D"

MAKER-P: A Tool Kit for the Rapid Creation, Management, and Quality Control of Plant Genome Annotations by Campbell, Michael S., Law, MeiYee, Holt, Carson, Stein, Joshua C., Moghe, Gaurav D., Hufnagel, David E., Lei, Jikai, Achawanantakun, Rujira, Jiao, Dian, Lawrence, Carolyn J., Ware, Doreen, Shiu, Shin-Han, Childs, Kevin L., Sun, Yanni, Jiang, Ning, Yandell, Mark

“…We have optimized and extended the widely used annotation engine MAKER in order to better support plant genome annotation efforts. New features include better…”
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Machine learning: A powerful tool for gene function prediction in plants by Mahood, Elizabeth H., Kruse, Lars H., Moghe, Gaurav D.

“…Recent advances in sequencing and informatic technologies have led to a deluge of publicly available genomic data. While it is now relatively easy to sequence,…”
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The study of plant specialized metabolism: Challenges and prospects in the genomics era by Moghe, Gaurav D., Kruse, Lars H.

“…Plants produce a diverse array of compounds through an extensive, evolutionarily malleable network of metabolic pathways. These metabolites are typically…”
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Untargeted metabolomics of purple and orange-fleshed sweet potatoes reveals a large structural diversity of anthocyanins and flavonoids by Bennett, Alexandra A., Mahood, Elizabeth H., Fan, Kai, Moghe, Gaurav D.

“…Anthocyanins are economically valuable phytochemicals of significant relevance to human health. Industrially extracted from multiple fruit and vegetable…”
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The causes and molecular consequences of polyploidy in flowering plants by Moghe, Gaurav D., Shiu, Shin-Han

“…Polyploidy is an important force shaping plant genomes. All flowering plants are descendants of an ancestral polyploid species, and up to 70% of extant…”
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Evolutionary routes to biochemical innovation revealed by integrative analysis of a plant-defense related specialized metabolic pathway by Moghe, Gaurav D, Leong, Bryan J, Hurney, Steven M, Daniel Jones, A, Last, Robert L

“…The diversity of life on Earth is a result of continual innovations in molecular networks influencing morphology and physiology. Plant specialized metabolism…”
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Characteristics of Plant Essential Genes Allow for within- and between-Species Prediction of Lethal Mutant Phenotypes by Lloyd, John P., Seddon, Alexander E., Moghe, Gaurav D., Simenc, Matthew C., Shiu, Shin-Han

“…Essential genes represent critical cellular components whose disruption results in lethality. Characteristics shared among essential genes have been uncovered…”
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Acylsugars protect Nicotiana benthamiana against insect herbivory and desiccation by Feng, Honglin, Acosta-Gamboa, Lucia, Kruse, Lars H., Tracy, Jake D., Chung, Seung Ho, Nava Fereira, Alba Ruth, Shakir, Sara, Xu, Hongxing, Sunter, Garry, Gore, Michael A., Casteel, Clare L., Moghe, Gaurav D., Jander, Georg

“…Key message Nicotiana benthamiana acylsugar acyltransferase (ASAT) is required for protection against desiccation and insect herbivory. Knockout mutations…”
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Coexpression Analysis Identifies Two Oxidoreductases Involved in the Biosynthesis of the Monoterpene Acid Moiety of Natural Pyrethrin Insecticides in Tanacetum cinerariifolium by Xu, Haiyang, Moghe, Gaurav D., Wiegert-Rininger, Krystle, Schilmiller, Anthony L., Barry, Cornelius S., Last, Robert L., Pichersky, Eran

“…Flowers of Tanacetum cinerariifolium produce a set of compounds known collectively as pyrethrins, which are commercially important pesticides that are strongly…”
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The push and pull of plant specialized metabolism underlies a long-standing, colorful mystery by Moghe, Gaurav D., Smith, Stacey D.

“…This article is a Commentary on Lopez‐Nieves et al., 217: 896–908…”
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Phylogenomic analyses across land plants reveals motifs and coexpression patterns useful for functional prediction in the BAHD acyltransferase family by Kruse, Lars H, Fehr, Benjamin, Chobirko, Jason D, Moghe, Gaurav D

“…The BAHD acyltransferase family is one of the largest enzyme families in flowering plants, containing dozens to hundreds of genes in individual genomes. Highly…”
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Evolutionary characteristics of intergenic transcribed regions indicate rare novel genes and widespread noisy transcription in the Poaceae by Lloyd, John P., Bowman, Megan J., Azodi, Christina B., Sowers, Rosalie P., Moghe, Gaurav D., Childs, Kevin L., Shiu, Shin-Han

“…Extensive transcriptional activity occurring in intergenic regions of genomes has raised the question whether intergenic transcription represents the activity…”
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Characteristics and Significance of Intergenic Polyadenylated RNA Transcription in Arabidopsis by Moghe, Gaurav D., Lehti-Shiu, Melissa D., Seddon, Alex E., Yin, Shan, Chen, Yani, Juntawong, Piyada, Brandizzi, Federica, Bailey-Serres, Julia, Shiu, Shin-Han

“…The Arabidopsis (Arabidopsis thaliana) genome is the most well-annotated plant genome. However, transcriptome sequencing in Arabidopsis continues to suggest…”
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Something Old, Something New: Conserved Enzymes and the Evolution of Novelty in Plant Specialized Metabolism by Moghe, Gaurav D., Last, Robert L.

“…Plants produce hundreds of thousands of small molecules known as specialized metabolites, many of which are of economic and ecological importance. This…”
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Growing a glue factory: Open questions in laticifer development by Johnson, Arielle R., Moghe, Gaurav D., Frank, Margaret H.

“…Latex-containing cells called laticifers are present in at least 41 flowering plant families and are thought to have convergently evolved at least 12 times…”
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Functionally Divergent Alleles and Duplicated Loci Encoding an Acyltransferase Contribute to Acylsugar Metabolite Diversity in Solanum Trichomes by Schilmiller, Anthony L., Moghe, Gaurav D., Fan, Pengxiang, Ghosh, Banibrata, Ning, Jing, Jones, A. Daniel, Last, Robert L.

“…Glandular trichomes from tomato (Solanum lycopersicum) and other species in the Solanaceae produce and secrete a mixture of O-acylsugars (aliphatic esters of…”
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Consequences of Whole-Genome Triplication as Revealed by Comparative Genomic Analyses of the Wild Radish Raphanus raphanistrum and Three Other Brassicaceae Species by Moghe, Gaurav D., Hufnagel, David E., Tang, Haibao, Xiao, Yongli, Dworkin, Ian, Town, Christopher D., Conner, Jeffrey K., Shiu, Shin-Han

“…Polyploidization events are frequent among flowering plants, and the duplicate genes produced via such events contribute significantly to plant evolution. We…”
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A Feedback-Insensitive Isopropylmalate Synthase Affects Acylsugar Composition in Cultivated and Wild Tomato by Ning, Jing, Moghe, Gaurav D., Leong, Bryan, Kim, Jeongwoon, Ofner, Itai, Wang, Zhenzhen, Adams, Christopher, Jones, A. Daniel, Zamir, Dani, Last, Robert L.

“…Acylsugars are insecticidal specialized metabolites produced in the glandular trichomes of plants in the Solanaceae family. In the tomato clade of…”
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Orthology‐based analysis helps map evolutionary diversification and predict substrate class use of BAHD acyltransferases by Kruse, Lars H., Weigle, Austin T., Irfan, Mohammad, Martínez‐Gómez, Jesús, Chobirko, Jason D., Schaffer, Jason E., Bennett, Alexandra A., Specht, Chelsea D., Jez, Joseph M., Shukla, Diwakar, Moghe, Gaurav D.

“…SUMMARY Large enzyme families catalyze metabolic diversification by virtue of their ability to use diverse chemical scaffolds. How enzyme families attain such…”
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Specialized Metabolism in a Nonmodel Nightshade: Trichome Acylinositol Biosynthesis by Leong, Bryan J, Hurney, Steven M, Fiesel, Paul D, Moghe, Gaurav D, Jones, A Daniel, Last, Robert L

“…Plants make many biologically active, specialized metabolites, which vary in structure, biosynthesis, and the processes they influence. An increasing number of…”
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