Search Results - "Moffett, Danielle"

Ubiquitin systems mark pathogen-containing vacuoles as targets for host defense by guanylate binding proteins by Haldar, Arun K., Foltz, Clémence, Finethy, Ryan, Piro, Anthony S., Feeley, Eric M., Pilla-Moffett, Danielle M., Komatsu, Masaki, Frickel, Eva-Maria, Coers, Jörn

“…Many microbes create and maintain pathogen-containing vacuoles (PVs) as an intracellular niche permissive for microbial growth and survival. The destruction of…”
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Galectin-3 directs antimicrobial guanylate binding proteins to vacuoles furnished with bacterial secretion systems by Feeley, Eric M., Pilla-Moffett, Danielle M., Zwack, Erin E., Piro, Anthony S., Finethy, Ryan, Kolb, Joseph P., Martinez, Jennifer, Brodsky, Igor E., Coers, Jörn

“…Many invasive bacteria establish pathogen-containing vacuoles (PVs) as intracellular niches for microbial growth. Immunity to these infections is dependent on…”
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Interferon-Inducible GTPases in Host Resistance, Inflammation and Disease by Pilla-Moffett, Danielle, Barber, Matthew F., Taylor, Gregory A., Coers, Jörn

“…Cell-autonomous immunity is essential for host organisms to defend themselves against invasive microbes. In vertebrates, both the adaptive and the innate…”
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Lipid-Encapsulated mRNAs Encoding Complex Fusion Proteins Potentiate Antitumor Immune Responses by Shuptrine, Casey W, Chen, Yuhui, Miriyala, Jayalakshmi, Lenz, Karen, Moffett, Danielle, Nguyen, Thuy-Ai, Michaux, Jenn, Campbell, Kristen, Smith, Connor, Morra, Marc, Rivera-Molina, Yisel, Murr, Noah, Cooper, Sarah, McGuire, Ashlyn, Makani, Vishruti, Oien, Nathan, Zugates, Jeffery T, de Silva, Suresh, Schreiber, Taylor H, de Picciotto, Seymour, Fromm, George

“…Lipid nanoparticle (LNP)-encapsulated mRNA has been used for in vivo production of several secreted protein classes, such as IgG, and has enabled the…”
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Mechanisms by Which Guanylate Binding Proteins Target Pathogen Vacuoles and Promote Caspase-11 Dependent Pyroptosis by Pilla-Moffett, Danielle

“…Guanylate binding proteins (Gbps) are a family of large GTPases that are highly stimulated by IFNγ and confer resistance to various viral, protozoan, and…”
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