Search Results - "Moeller, Jesper V."

Stoichiometry of lipid–protein interaction assessed by hydrophobic photolabeling by Giraldo, Ana María Villamil, Castello, Pablo Raúl, Flecha, F. Luis González, Moeller, Jesper V., Delfino, José María, Rossi, Juan Pablo F.C.

“…Here we undertook a comparative study of the composition of the lipid annulus of three ATPases pertaining to the P-type family: plasma membrane calcium pump…”
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P-type ATPases as drug targets: Tools for medicine and science by Yatime, Laure, Buch-Pedersen, Morten J., Musgaard, Maria, Morth, J. Preben, Winther, Anne-Marie Lund, Pedersen, Bjørn P., Olesen, Claus, Andersen, Jens Peter, Vilsen, Bente, Schiøtt, Birgit, Palmgren, Michael G., Møller, Jesper V., Nissen, Poul, Fedosova, Natalya

“…P-type ATPases catalyze the selective active transport of ions like H +, Na +, K +, Ca 2+, Zn 2+, and Cu 2+ across diverse biological membrane systems. Many…”
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Binding of a nonionic detergent to membranes: flip-flop rate and location on the bilayer by Le Maire, Marc, Moeller, Jesper V, Champeil, Philippe

“…The kinetic aspects of amphiphile interaction with intact membranes (unilamellar and multilamellar liposomes, sarcoplasmic reticulum vesicles) were studied,…”
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Transitional steps in the solubilization of protein-containing membranes and liposomes by nonionic detergent by Kragh-Hansen, Ulrich, Le Maire, Marc, Noel, Jean Pierre, Gulik-Krzywicki, Tadeusz, Moeller, Jesper V

“…Membrane solubilization by dodecyl maltoside was studied, using Ca(2+)-ATPase membranes and liposome preparations as prototypes of biological membranes. In…”
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Comparing crystal structures of Ca²⁺‐ATPase in the presence of different lipids by Drachmann, Nikolaj D, Olesen, Claus, Møller, Jesper V, Guo, Zheng, Nissen, Poul, Bublitz, Maike

“…The activity of the sarco/endoplasmic reticulum Ca²⁺‐ATPase (SERCA) depends strongly on the lipid composition of the surrounding membrane. Yet, structural…”
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Differential effects of thapsigargin analogues on apoptosis of prostate cancer cells: Complex regulation by intracellular calcium by Dubois, Charlotte, Vanden Abeele, Fabien, Sehgal, Pankaj, Olesen, Claus, Junker, Steffen, Christensen, Søren B, Prevarskaya, Natalia, Møller, Jesper V

“…The inhibition of sarcoplasmic reticulum Ca²⁺‐ATPase (SERCA) by thapsigargin (Tg) and Tg‐type analogues is considered to trigger cell death by activation of…”
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Critical Roles of Hydrophobicity and Orientation of Side Chains for Inactivation of Sarcoplasmic Reticulum Ca2+-ATPase with Thapsigargin and Thapsigargin Analogs by Winther, Anne-Marie L., Liu, Huizhen, Sonntag, Yonathan, Olesen, Claus, le Maire, Marc, Soehoel, Helmer, Olsen, Carl-Erik, Christensen, S. Brøgger, Nissen, Poul, Møller, Jesper V.

“…Thapsigargin (Tg), a specific inhibitor of sarco/endoplasmic Ca2+-ATPases (SERCA), binds with high affinity to the E2 conformation of these ATPases. SERCA…”
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Purified E255L Mutant SERCA1a and Purified PfATP6 Are Sensitive to SERCA-type Inhibitors but Insensitive to Artemisinins by Cardi, Delphine, Pozza, Alexandre, Arnou, Bertrand, Marchal, Estelle, Clausen, Johannes D., Andersen, Jens Peter, Krishna, Sanjeev, Møller, Jesper V., le Maire, Marc, Jaxel, Christine

“…The antimalarial drugs artemisinins have been described as inhibiting Ca2+-ATPase activity of PfATP6 (Plasmodium falciparum ATP6) after expression in Xenopus…”
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Slow Phospholipid Exchange between a Detergent-Solubilized Membrane Protein and Lipid-Detergent Mixed Micelles: Brominated Phospholipids as Tools to Follow Its Kinetics by Montigny, Cédric, Dieudonné, Thibaud, Orlowski, Stéphane, Vázquez-Ibar, José Luis, Gauron, Carole, Georgin, Dominique, Lund, Sten, le Maire, Marc, Møller, Jesper V, Champeil, Philippe, Lenoir, Guillaume

“…Membrane proteins are largely dependent for their function on the phospholipids present in their immediate environment, and when they are solubilized by…”
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Crystallization of a Mammalian Membrane Protein Overexpressed in Saccharomyces cerevisiae by Jidenko, Marie, Nielsen, Rikke C., Sørensen, Thomas Lykke-Møller, Møller, Jesper V., le Maire, Marc, Nissen, Poul, Jaxel, Christine, Kaback, H. Ronald

“…The Ca2+- ATPase SERCA1a (sarcoplasmic-endoplasmic reticulum Ca2+- ATPase isoform 1a) from rabbit has been overexpressed in Saccharomyces cerevisiae. This…”
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Natural products as starting materials for development of second-generation SERCA inhibitors targeted towards prostate cancer cells by Søhoel, Helmer, Jensen, Anne-Marie Lund, Møller, Jesper V., Nissen, Poul, Denmeade, Samuel R., Isaacs, John T., Olsen, Carl Erik, Christensen, S. Brøgger

“…An analysis of the binding of the 8- O- N- tert-butoxycarbonyl-12-aminododecanoyl derivative of 8- O-debutanoylthapsigargin to the target molecule, the SERCA…”
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Gel chromatography and analytical ultracentrifugation to determine the extent of detergent binding and aggregation, and Stokes radius of membrane proteins using sarcoplasmic reticulum Ca super(2+)-ATPase as an example by Le Maire, Marc, Arnou, Bertrand, Olesen, Claus, Georgin, Dominique, Ebel, Christine, Moeller, Jesper V

“…For structural studies of integral membrane proteins, including their 3D crystallization, the judicious use of detergent for solubilization and purification is…”
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Characterization of detergent-solubilized sarcoplasmic reticulum calcium ATPase by high-performance liquid chromatography by Andersen, Jens P, Vilsen, Bente, Nielsen, Henning, Moeller, Jesper V

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Membrane solubilization by detergent: use of brominated phospholipids to evaluate the detergent-induced changes in calcium-ATPase/lipid interaction by De Foresta, Beatrice, Le Maire, Marc, Orlowski, Stephane, Champeil, Philippe, Lund, Sten, Moeller, Jesper V, Michelangeli, Francesco, Lee, Anthony G

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The sarcoplasmic Ca2+-ATPase: design of a perfect chemi-osmotic pump by Møller, Jesper V, Olesen, Claus, Winther, Anne-Marie L, Nissen, Poul

“…The sarcoplasmic (SERCA 1a) Ca2+-ATPase is a membrane protein abundantly present in skeletal muscles where it functions as an indispensable component of the…”
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Transport mechanism of the sarcoplasmic reticulum Ca super(2+)-ATPase pump by Moeller, Jesper V, Nissen, Poul, Soerensen, Thomas L-M, Le Maire, Marc

“…The sarcoplasmic reticulum Ca super(2+)-ATPase (SERCA1a) belongs to the group of P-type ATPases, which actively transport inorganic cations across membranes at…”
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Immobilization of a spin-labeled fatty acid chain covalently attached to calcium(2+)-ATPase from sarcoplasmic reticulum suggests an oligomeric structure by Andersen, Jens P, Fellmann, Pierre, Moeller, Jesper V, Devaux, Philippe F

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Involvement of the L6-7 Loop in SERCA1a Ca super(2+)-ATPase Activation by Ca super(2+) (or Sr super(2+)) and ATP by Lenoir, Guillaume, Picard, Martin, Moeller, Jesper V, Le Maire, Marc, Champeil, Philippe, Falson, Pierre

“…Wild-type (WT) and the double mutant D813A,D818A (ADA) of the L6-7 loop of SERCA1a were expressed in yeast, purified, and reconstituted into lipids. This…”
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Corrigendum to “Stoichiometry of lipid–protein interaction assessed by hydrophobic photolabeling” [FEBS Lett. 580 (2006) 607–612] by Giraldo, Ana María Villamil, Castello, Pablo Raúl, Flecha, F. Luis González, Moeller, Jesper V., Delfino, José María, Rossi, Juan Pablo F.C.

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Retention of enzyme activity by detergent-solubilized sarcoplasmic Ca2+ion-activated ATPase by Le Maire, Marc, Moeller, Jesper V, Tanford, Charles

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