Search Results - "Moebus, Lena"
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Epigenetic factors involved in the pathophysiology of inflammatory skin diseases
Published in Journal of allergy and clinical immunology (01-04-2020)“…Epigenetics has been discussed as a potential factor influencing the pathophysiology and severity of inflammatory skin diseases. In recent years, emerging…”
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Regression of melanoma metastases and multiple non-melanoma skin cancers in xeroderma pigmentosum by the PD1-antibody pembrolizumab
Published in European journal of cancer (1990) (01-05-2017)“…Xeroderma pigmentosum (XP) is a rare autosomal-recessive disorder caused by defects in the nucleotide excision repair, a DNA repair system which is responsible…”
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Blood transcriptome profiling identifies 2 candidate endotypes of atopic dermatitis
Published in Journal of allergy and clinical immunology (01-08-2022)“…Few studies have analyzed the blood transcriptome in atopic dermatitis (AD). We explored blood transcriptomic features of moderate to severe AD. Blood…”
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Elevated NK-cell transcriptional signature and dysbalance of resting and activated NK cells in atopic dermatitis
Published in Journal of allergy and clinical immunology (01-05-2021)“…Altered quantities, activity, and composition of natural killer (NK) cells in blood as well as expression changes of genes involved in NK-cell function in skin…”
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Platelet-Released Growth Factors and Platelet-Rich Fibrin Induce Expression of Factors Involved in Extracellular Matrix Organization in Human Keratinocytes
Published in International journal of molecular sciences (20-06-2020)“…Platelet-released growth factor (PRGF) is a thrombocyte concentrate lysate which, like its clinically equivalent variations (e.g., Vivostat PRF (platelet-rich…”
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Ancient DNA study reveals HLA susceptibility locus for leprosy in medieval Europeans
Published in Nature communications (01-05-2018)“…Leprosy, a chronic infectious disease caused by Mycobacterium leprae ( M. leprae ), was very common in Europe till the 16th century. Here, we perform an…”
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Staphylococcus aureus Activates the Aryl Hydrocarbon Receptor in Human Keratinocytes
Published in Journal of innate immunity (01-12-2022)“…Abstract Staphylococcus aureus is an important pathogen causing various infections, including – as most frequently isolated bacterium – cutaneous infections…”
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Platelet-Released Growth Factors Induce Genes Involved in Extracellular Matrix Formation in Human Fibroblasts
Published in International journal of molecular sciences (01-10-2021)“…Platelet concentrate products are increasingly used in many medical disciplines due to their regenerative properties. As they contain a variety of chemokines,…”
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Hypomorphic CARD11 mutations associated with diverse immunologic phenotypes with or without atopic disease
Published in Journal of allergy and clinical immunology (28-08-2018)“…This description of a large cohort of patients broadens the spectrum of clinical disease phenotypes linked to CARD11 DN mutations, including atopy, cutaneous…”
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