Search Results - "Modzelewska, Katarzyna"

MYC-Driven Small-Cell Lung Cancer is Metabolically Distinct and Vulnerable to Arginine Depletion by Chalishazar, Milind D, Wait, Sarah J, Huang, Fang, Ireland, Abbie S, Mukhopadhyay, Anandaroop, Lee, Younjee, Schuman, Sophia S, Guthrie, Matthew R, Berrett, Kristofer C, Vahrenkamp, Jeffery M, Hu, Zeping, Kudla, Marek, Modzelewska, Katarzyna, Wang, Guoying, Ingolia, Nicholas T, Gertz, Jason, Lum, David H, Cosulich, Sabina C, Bomalaski, John S, DeBerardinis, Ralph J, Oliver, Trudy G

“…Small-cell lung cancer (SCLC) has been treated clinically as a homogeneous disease, but recent discoveries suggest that SCLC is heterogeneous. Whether…”
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MEK Inhibitors Reverse Growth of Embryonal Brain Tumors Derived from Oligoneural Precursor Cells by Modzelewska, Katarzyna, Boer, Elena F., Mosbruger, Timothy L., Picard, Daniel, Anderson, Daniela, Miles, Rodney R., Kroll, Mitchell, Oslund, William, Pysher, Theodore J., Schiffman, Joshua D., Jensen, Randy, Jette, Cicely A., Huang, Annie, Stewart, Rodney A.

“…Malignant brain tumors are the leading cause of cancer-related deaths in children. Primitive neuroectodermal tumors of the CNS (CNS-PNETs) are particularly…”
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Neurons refine the Caenorhabditis elegans body plan by directing axial patterning by Wnts by Modzelewska, Katarzyna, Lauritzen, Amara, Hasenoeder, Stefan, Brown, Louise, Georgiou, John, Moghal, Nadeem

“…Metazoans display remarkable conservation of gene families, including growth factors, yet somehow these genes are used in different ways to generate tremendous…”
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Ack1 Mediates Cdc42-dependent Cell Migration and Signaling to p130Cas by Modzelewska, Katarzyna, Newman, Laura P., Desai, Radhika, Keely, Patricia J.

“…We previously showed that activation of the small GTPase Cdc42 promotes breast cell migration on a collagen matrix. Here we further define the signaling…”
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An Activating Mutation in sos-1 Identifies Its Dbl Domain as a Critical Inhibitor of the Epidermal Growth Factor Receptor Pathway during Caenorhabditis elegans Vulval Development by Modzelewska, Katarzyna, Elgort, Marc G., Huang, Jingyu, Jongeward, Gregg, Lauritzen, Amara, Yoon, Charles H., Sternberg, Paul W., Moghal, Nadeem

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Sensory regulated Wnt production from neurons helps make organ development robust to environmental changes in C. elegans by Modzelewska, Katarzyna, Brown, Louise, Culotti, Joseph, Moghal, Nadeem

“…Long-term survival of an animal species depends on development being robust to environmental variations and climate changes. We used to study how mechanisms…”
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Focal adhesion regulation of cell behavior by Wozniak, Michele A, Modzelewska, Katarzyna, Kwong, Lina, Keely, Patricia J

“…Focal adhesions lie at the convergence of integrin adhesion, signaling and the actin cytoskeleton. Cells modify focal adhesions in response to changes in the…”
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Systematic single amino acid affinity tuning of CD229 CAR T cells retains efficacy against multiple myeloma and eliminates on-target off-tumor toxicity by Vander Mause, Erica R, Baker, Jillian M, Dietze, Kenneth A, Radhakrishnan, Sabarinath V, Iraguha, Thierry, Omili, Destiny, Davis, Patricia, Chidester, Sadie L, Modzelewska, Katarzyna, Panse, Jens, Marvin, James E, Olson, Michael L, Steinbach, Mary, Ng, David P, Lim, Carol S, Atanackovic, Djordje, Luetkens, Tim

“…T cells expressing chimeric antigen receptors (CARs) have shown remarkable therapeutic activity against different types of cancer. However, the wider use of…”
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Allele-specific gene regulation, phenotypes, and therapeutic vulnerabilities in estrogen receptor alpha mutant endometrial cancer by Blanchard, Zannel, Rush, Craig M, Arnesen, Spencer, Vahrenkamp, Jeffery M, Rodriguez, Adriana C, Jarboe, Elke A, Brown, Callie, Chang, Matthew E K, Flory, Mark R, Mohammed, Hisham, Modzelewska, Katarzyna, Lum, David H, Gertz, Jason

“…Activating estrogen receptor alpha (ER) mutations are present in primary endometrial and metastatic breast cancers, promoting estrogen-independent activation…”
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Sensory regulated Wnt production from neurons helps make organ development robust to environmental changes in C. elegans by Modzelewska, Katarzyna, Brown, Louise, Culotti, Joseph, Moghal, Nadeem

“…Long-term survival of an animal species depends on development being robust to environmental variations and climate changes. We used C. elegans to study how…”
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Transplantation of Zebrafish Pediatric Brain Tumors into Immune-competent Hosts for Long-term Study of Tumor Cell Behavior and Drug Response by Casey, Mattie J, Modzelewska, Katarzyna, Anderson, Daniela, Goodman, James, Boer, Elena F, Jimenez, Laura, Grossman, Douglas, Stewart, Rodney A

“…Tumor cell transplantation is an important technique to define the mechanisms controlling cancer cell growth, migration, and host response, as well as to…”
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Transplantation of Zebrafish Pediatric Brain Tumors into Immune-competent Hosts for Long-term Study of Tumor Cell Behavior and Drug Response by Casey, Mattie J., Modzelewska, Katarzyna, Anderson, Daniela, Goodman, James, Boer, Elena F., Jimenez, Laura, Grossman, Douglas, Stewart, Rodney A.

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PM-12USING A ZEBRAFISH PEDIATRIC BRAIN TUMOR MODEL FOR PRE-CLINICAL DRUG SCREENING by Modzelewska, Katarzyna, Picard, Daniel, Boer, Elena, Miles, Rodney, Jensen, Randy, Pysher, Theodore, Schiffman, Joshua, Jette, Cicely, Huang, Annie, Stewart, Rodney

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The marine alkaloid naamidine A promotes caspase-dependent apoptosis in tumor cells by LaBarbera, Daniel V, Modzelewska, Katarzyna, Glazar, Amanda I, Gray, Phillip D, Kaur, Manjinder, Liu, Tong, Grossman, Douglas, Harper, Mary Kay, Kuwada, Scott K, Moghal, Nadeem, Ireland, Chris M

“…Apoptosis is important for normal development and removal of damaged cells. Evasion of apoptosis by cancer cells is one of the key characteristics of many…”
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Ack1 Mediates Cdc42-dependent Cell Migration and Signaling to p130 super(Cas) by Modzelewska, Katarzyna, Newman, Laura P, Desai, Radhika, Keely, Patricia J

“…We previously showed that activation of the small GTPase Cdc42 promotes breast cell migration on a collagen matrix. Here we further define the signaling…”
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Ack1 tyrosine kinase regulates collagen-induced signaling and cell migration by Modzelewska, Katarzyna

“…The loss of epithelial polarization and the acquisition of a migratory phenotype is a key determinant of breast cancer progression, which ultimately leads to…”
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