Search Results - "Mody, Meera"

Activation of Villous Trophoblastic p38 and ERK1/2 Signaling Pathways in Preterm Preeclampsia and HELLP Syndrome by Szabo, Szilvia, Mody, Meera, Romero, Roberto, Xu, Yi, Karaszi, Katalin, Mihalik, Noemi, Xu, Zhonghui, Bhatti, Gaurav, Fule, Tibor, Hupuczi, Petronella, Krenacs, Tibor, Rigo, Janos, Tarca, Adi L., Hassan, Sonia S., Chaiworapongsa, Tinnakorn, Kovalszky, Ilona, Papp, Zoltan, Than, Nandor Gabor

“…Preterm preeclampsia is associated with the failure of trophoblast invasion, placental hypoxic/ischemic injury and the release of toxic substances, which…”
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A rabbit model for monitoring in vivo viability of human platelet concentrates using flow cytometry by Leytin, Valery, Allen, David J., Mody, Meera, Rand, Margaret L., Hannach, Barbara, Garvey, Bernadette, Freedman, John

“…BACKGROUND : Viability in vivo of novel platelet components cannot be readily determined in human transfusions. Elaboration of valid animal models may be…”
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Flow cytometric analysis of platelet function in stored platelet concentrates by Wang, Chen, Mody, Meera, Herst, Roslyn, Sher, Graham, Freedman, John

“…Platelet activation occurs during the collection, processing and storage of platelet concentrates. The effect of the platelet activation on the functional…”
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Differences in Serum Cytokine Levels in Acute and Chronic Autoimmune Thrombocytopenic Purpura: Relationship to Platelet Phenotype and Antiplatelet T-Cell Reactivity by Semple, John W., Milev, Youli, Cosgrave, Donna, Mody, Meera, Hornstein, Adriana, Blanchette, Victor, Freedman, John

“…Patients with both acute and chronic autoimmune thrombocytopenic purpura (AITP) have in vitro lymphocyte defects in the form of platelet-stimulated…”
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Flow Cytometric Parameters for Characterizing Platelet Activation by Measuring P-Selectin (CD62) Expression: Theoretical Consideration and Evaluation in Thrombin-Treated Platelet Populations by Leytin, Valery, Mody, Meera, Semple, John W., Garvey, Bernadette, Freedman, John

“…Two flow cytometric parameters are generally used to quantify platelet activation as measured by P-selectin (CD62) expression: percentage and mean channel…”
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Hemolink™, an o‐raffinose cross‐linked haemoglobin‐based oxygen carrier, does not affect activation and function of human platelets in whole blood in vitro by Leytin, Valery, Mazer, David, Mody, Meera, Garvey, Bernadette, Freedman, John

“…Haemoglobin‐based oxygen carriers (HBOCs) are anticipated to be safe and efficient alternatives to RBC transfusions. Haemoglobin (Hb) raffimer (Hemolink™;…”
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Hemolink, an o-raffinose cross-linked haemoglobin-baseed oxygen carrier, does not affect activation and function of human platelets in whold blood in vitro by Leytin, Valery, Mazer, David, Mody, Meera, Garvey, Bernadette, Freedman, John

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Quantification of Platelet Activation Status by Analyzing P-Selectin Expression by Leytin, Valery, Mody, Meera, Semple, John W., Garvey, Bernadette, Freedman, John

“…Platelet activation status (PAS) is used for characterizing quality and function of platelets in various experimental and clinical settings. In this study, we…”
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The relationship of von Willebrand factor binding to activated platelets from healthy neonates and adults by SCHMUGGE, Markus, RAND, Margaret Lucille, BANG, Kyong Won, MODY, Meera, DUNN, Michael Stephen, AMANKWAH, Kofi Sarpong, BLANCHETTE, Victor Stanley, FREEDMAN, John

“…von Willebrand Factor (VWF) is important in platelet adhesion and shear-dependent platelet activation. We performed flow cytometric analyses of VWF binding to…”
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Sepsis- and endotoxemia-generated cytokines do not trigger activation of human platelets by Leytin, Valery, Shakoor, Samantha, Mody, Meera, Allen, David, Garvey, Bernadette, Freedman, John

“…OBJECTIVETo analyze the effect of cytokines generated in sepsis and endotoxemia (tumor necrosis factor [TNF]-α and interleukins [IL]-1β, -6, and -8) on…”
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Flow cytometric analysis of platelets from children with the Wiskott-Aldrich syndrome reveals defects in platelet development, activation and structure by SEMPLE, J. W, SIMINOVITCH, K. A, MODY, M, MILEV, Y, LAZARUS, A. H, WRIGHT, J. F, FREEDMAN, J

“…The pathophysiology of platelet dysfunction in the Wiskott-Aldrich immune deficiency syndrome (WAS) remains unclear. Using flow cytometry, we have…”
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p38 MAPK is activated but not necessary in porcine von Willebrand factor‐dependent platelet activation by Song, Seng, Freedman, John, Mody, Meera, Lazarus, Alan H.

“…We have investigated the role of p38 mitogen‐activated protein kinase (MAPK) in von Willebrand factor (VWF)‐dependent platelet activation. The interaction of…”
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Porcine von Willebrand factor and thrombin induce the activation of c‐Jun amino‐terminal kinase (JNK/SAPK) whereas only thrombin induces activation of extracellular signal‐related kinase 2 (ERK2) in human platelets by Song, Seng, Freedman, John, Mody, Meera, Lazarus, Alan H.

“…The interaction of platelets with subendothelial von Willebrand factor (VWF), especially under high shear stress, is considered to be the first activation step…”
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Characterization of HIV‐1‐specific antibodies and HIV‐1‐crossreactive antibodies to platelets in HIV‐1‐infected haemophiliac patients by Chia, Wah Kiam, Blanchette, Victor, Mody, Meera, Wright, J. Fraser, Freedman, John

“…Sera from HIV‐1‐infected haemophiliacs were examined for human immunodeficiency virus (HIV) specific antibodies and for platelet crossreactive antibodies…”
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Blood platelet adhesion to protein studied by on-line acoustic wave sensor by Cavic, B A, Freedman, J, Morel, Z, Mody, M, Rand, M L, Stone, D C, Thompson, M

“…The attachment of blood platelets to the surface of bare and protein-coated thickness-shear mode acoustic wave devices operating in a flow-through…”
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Platelet-surface glycoproteins in healthy and preeclamptic mothers and their newborn infants by KÜHNE, T, RYAN, G, BLANCHETTE, V, SEMPLE, J. W, HORNSTEIN, A, MODY, M, CHANG, W, MCWHIRTER, L, FREEDMAN, J

“…Preeclampsia, a common complication of pregnancy, contributes significantly to maternal and fetal morbidity and mortality. It may lead to both quantitative and…”
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Flow cytometric analysis of platelets from childrenwith the Wiskott‐Aldrich syndrome reveals defects in platelet development, activation and structure by Semple, John W., Siminovitch, Katherine A., Mody, Meera, Milev, Youli, Lazarus, Alan H., Wright, J. Fraser, Freedman, John

“…The pathophysiology of platelet dysfunction in the Wiskott‐Aldrich immune deficiency syndrome (WAS) remains unclear. Using flow cytometry, we have…”
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Comparison of platelet immunity in patients with SLE and with ITP by Lazarus, Alan H, Ellis, Janet, Semple, John W, Mody, Meera, Crow, Andrew R, Freedman, John

“…Idiopathic thrombocytopenic purpura (ITP) is characterized by the development of a specific anti-platelet autoantibody immune response mediating the…”
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