Search Results - "Modur, Vijayanand"

FOXO proteins regulate tumor necrosis factor-related apoptosis inducing ligand expression. Implications for PTEN mutation in prostate cancer by Modur, Vijayanand, Nagarajan, Rakesh, Evers, B Mark, Milbrandt, Jeffrey

“…Mutations in PTEN occur in 60-80% of prostate cancers and lead to a constitutive activation of the phosphatidylinositol 3-kinase pathway and a resultant loss…”
Get full text

FOXO Proteins Regulate Tumor Necrosis Factor-related Apoptosis Inducing Ligand Expression by Modur, Vijayanand, Nagarajan, Rakesh, Evers, B. Mark, Milbrandt, Jeffrey

“…Mutations in PTEN occur in 60–80% of prostate cancers and lead to a constitutive activation of the phosphatidylinositol 3-kinase pathway and a resultant loss…”
Get full text

Endothelial cell inflammatory responses to tumor necrosis factor alpha. Ceramide-dependent and -independent mitogen-activated protein kinase cascades by Modur, V, Zimmerman, G A, Prescott, S M, McIntyre, T M

“…Ceramide generation by stimulated sphingomyelinase activity has been implicated in tumor necrosis factor alpha (TNF) signaling of apoptosis and…”
Get full text

Retrograde inflammatory signaling from neutrophils to endothelial cells by soluble interleukin-6 receptor alpha by Modur, V, Li, Y, Zimmerman, G A, Prescott, S M, McIntyre, T M

“…Endothelial cells initiate the inflammatory response by recruiting and activating leukocytes. IL-6 is not an agonist for this, but we found soluble IL-6…”
Get full text

Oncostatin M is a proinflammatory mediator. In vivo effects correlate with endothelial cell expression of inflammatory cytokines and adhesion molecules by Modur, V, Feldhaus, M J, Weyrich, A S, Jicha, D L, Prescott, S M, Zimmerman, G A, McIntyre, T M

“…Oncostatin M is a member of the IL-6 family of cytokines that is primarily known for its effects on cell growth. Endothelial cells have an abundance of…”
Get full text

Borrelia burgdorferi outer membrane protein A induces nuclear translocation of nuclear factor-kappa B and inflammatory activation in human endothelial cells by Wooten, RM, Modur, VR, McIntyre, TM, Weis, JJ

“…Lyme disease is caused by infection with Borrelia burgdorferi, and is characterized by bacterial persistence and inflammation in a number of host tissues. B…”
Get full text

Fluid flow activates a regulator of translation, p70/p85 S6 kinase, in human endothelial cells by Kraiss, L W, Weyrich, A S, Alto, N M, Dixon, D A, Ennis, T M, Modur, V, McIntyre, T M, Prescott, S M, Zimmerman, G A

“…Cellular phenotype is determined not only by genetic transcription but also by subsequent translation of mRNA into protein. Extracellular signals trigger…”
Get more information

The necrotic venom of the brown recluse spider induces dysregulated endothelial cell-dependent neutrophil activation. Differential induction of GM-CSF, IL-8, and E-selectin expression by Patel, K D, Modur, V, Zimmerman, G A, Prescott, S M, McIntyre, T M

“…Brown recluse spider (Loxosceles reclusa) venom induces severe dermonecrotic lesions. The mechanism for this is unknown but presents an interesting paradox:…”
Get full text

Molecular mechanisms of early inflammation by McIntyre, T M, Modur, V, Prescott, S M, Zimmerman, G A

Get more information

Endothelial Cell Inflammatory Responses to Tumor Necrosis Factor Î by Vijayanand Modur, Guy A. Zimmerman, Stephen M. Prescott, Thomas M. McIntyre

“…Ceramide generation by stimulated sphingomyelinase activity has been implicated in tumor necrosis factor α (TNF) signaling of apoptosis and differentiation…”
Get full text

Endothelial Cell Inflammatory Responses to Tumor Necrosis Factor α by Modur, Vijayanand, Zimmerman, Guy A., Prescott, Stephen M., McIntyre, Thomas M.

Get full text

Cytokine signaling in endothelial cells by Modur, Vijayanand R

“…Endothelial cells mediate the inflammatory response by coordinating localization and activation of leukocytes via a concerted expression of adhesion molecules…”
Get full text