Search Results - "Modrego, Pedro J."

The risk of symptomatic intracranial hemorrhage after thrombolysis for acute stroke: Current concepts and perspectives by Modrego, Pedro

“…Background: Thrombolysis is the standard of treatment for acute ischemic stroke, with a time window of up to 4½ h from stroke onset. Despite the long…”
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Higher Glutamate + Glutamine and Reduction of N -acetylaspartate in Posterior Cingulate According to Age Range in Patients with Cognitive Impairment and/or Pain by Fayed, Nicolás, PhD, Andrés, Eva, PhD, Viguera, Laura, MD, Modrego, Pedro J., PhD, Garcia-Campayo, Javier, PhD

“…Rationale and Objectives The aim of the study was to analyze 1) whether the metabolite levels in the posterior cingulate cortex (PCC) are different in healthy…”
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The interface between depression and alzheimer's disease. A comprehensive approach by Modrego, Pedro, de Cerio, Leyre, Lobo, Antonio

“…Depression and Alzheimer's disease (AD) are frequent interacting diseases in the elderly with a negative impact on the quality of life of patients and…”
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Magnetic resonance spectroscopy in the prediction of early conversion from amnestic mild cognitive impairment to dementia: a prospective cohort study by Modrego, Pedro J, Fayed, Nicolas, Sarasa, Manuel

“…BackgroundMild cognitive impairment (MCI) of an amnestic type is a common condition in older people and highly predictive of Alzheimer's disease (AD). To date,…”
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Conversion From Mild Cognitive Impairment to Probable Alzheimer's Disease Predicted by Brain Magnetic Resonance Spectroscopy by Modrego, Pedro J., Fayed, Nicolás, Pina, Miguel A.

“…OBJECTIVE: Mild cognitive impairment has been regarded as a pre-Alzheimer condition, but some patients do not develop dementia. Given the available therapies…”
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Longitudinal Magnetic Resonance Spectroscopy as Marker of Cognitive Deterioration in Mild Cognitive Impairment by Modrego, Pedro J., Fayed, Nicolás

“…Objective: Amnestic mild cognitive impairment (MCI) is highly predictive of Alzheimer’s disease but the pace of deterioration varies across patients. We…”
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Behavioral Symptoms Improve Prediction Models of Mortality in Patients With Dementia by Modrego, Pedro J

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Frontal Dysexecutive Syndrome in Brain Tumors: A Pragmatic Insight to an Old Problem by Dubey, Souvik, Ghosh, Ritwik, Chatterjee, Subhankar, Dubey, Mahua Jana, Sengupta, Samya, Chatterjee, Subham, Kanti Ray, Biman, Modrego, Pedro J., Benito-León, Julián

“…Brain tumors have long been considered one of the most prevalent causes of potentially reversible cognitive impairment. An accurate underlying cause of…”
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Correlation of Findings in Advanced MRI Techniques with Global Severity Scales in Patients with Parkinson Disease by Modrego, Pedro J., MD, Fayed, Nicolás, MD, Artal, Jorge, MD, Olmos, Salvador, PhD

“…Rationale and Objectives This work is aimed at determining whether magnetic resonance spectroscopy (MRS) and diffusion tensor imaging (DTI) may correlate with…”
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Depression in Alzheimer's disease. Pathophysiology, diagnosis, and treatment by Modrego, Pedro J

“…Depression is a comorbid condition in Alzheimer's disease (AD) with negative consequences in patients and caregivers. Pathophysiology and optimal treatment are…”
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Retinal alterations in mild cognitive impairment and Alzheimer’s disease: an optical coherence tomography study by Ascaso, Francisco J., Cruz, Nancy, Modrego, Pedro J., Lopez-Anton, Raul, Santabárbara, Javier, Pascual, Luis F., Lobo, Antonio, Cristóbal, José A.

“…Retinal nerve fiber layer thickness (RNFL) measured by means of Optical Coherence Tomography (OCT) has been used as a marker not only of ophthalmologic…”
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Retinal nerve fiber layer and macular thickness in patients with schizophrenia: Influence of recent illness episodes by Ascaso, Francisco J, Rodriguez-Jimenez, Roberto, Cabezón, Laura, López-Antón, Raúl, Santabárbara, Javier, De la Cámara, Concepción, Modrego, Pedro J, Quintanilla, Miguel A, Bagney, Alexandra, Gutierrez, Leticia, Cruz, Nancy, Cristóbal, José A, Lobo, Antonio

“…Abstract Optical coherence tomography (OCT) has been recently used to investigate neuropsychiatric disorders. We aimed to study retinal OCT measures of…”
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Brain Glutamate Levels Are Decreased in Alzheimer’s Disease: A Magnetic Resonance Spectroscopy Study by Fayed, Nicolas, Modrego, Pedro J., Rojas-Salinas, Guillermo, Aguilar, Keyla

“…Glutamate (Glu) is the most abundant excitatory neurotransmitter in the central nervous system (CNS) and is involved in the pathophysiology of Alzheimer’s…”
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Cerebellar vermis: a vulnerable location of remote brain haemorrhages after thrombolysis for ischaemic stroke by Tejada-Meza, Herbert, Modrego, Pedro J.

“…Extra-ischaemic (remote) brain heamorrhages after thrombolysis for ischaemic stroke occur in less than 3 % of treated patients, but it worsens prognosis…”
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Myasthenia gravis: the unmet needs of a paradigmatic autoimmune disease by Modrego, Pedro J

“…In some cases, MG is detected immediately after a surgical intervention when the patient is weaned off the respiratory support. Since more than two decades…”
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Magnetic resonance spectroscopy and brain volumetry in mild cognitive impairment. A prospective study by Fayed, Nicolás, Modrego, Pedro J, García-Martí, Gracián, Sanz-Requena, Roberto, Marti-Bonmatí, Luis

“…Abstract Objective To assess the accuracy of magnetic resonance spectroscopy (1H-MRS) and brain volumetry in mild cognitive impairment (MCI) to predict…”
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The effects of pregnancy on relapse rates, disability and peripartum outcomes in women with multiple sclerosis: a systematic review and meta-analysis by Modrego, Pedro J, Urrea, Maria Añaños, de Cerio, Leyre Diaz

“…Although previous cohort studies of women with multiple sclerosis (MS) yielded a reduction in relapse rate during pregnancy, the effect size has not been…”
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Evidence of brain damage after high-altitude climbing by means of magnetic resonance imaging by Fayed, Nicolás, Modrego, Pedro J, Morales, Humberto

“…There are only anecdotal and small reports on brain systematic magnetic resonance imaging (MRI) studies in mountain climbers. The purpose of our work is to…”
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Predictors of conversion to dementia of probable Alzheimer type in patients with mild cognitive impairment by Modrego, Pedro J

“…Mild Cognitive Impairment is a common condition defined as transitional state between normality and dementia of Alzheimer type. Clinically is characterized by…”
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Comparative test-retest reliability of metabolite values assessed with magnetic resonance spectroscopy of the brain. The LCModel versus the manufacturer software by Fayed, Nicolas, Modrego, Pedro J., Medrano, Jaime

“…Objective: Reproducibility is an essential strength of any diagnostic technique for cross-sectional and longitudinal works. To determine in vivo short-term…”
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