Search Results - "Modderman, P W"

Laminin receptor on platelets is the integrin VLA-6 by Sonnenberg, Arnoud, Modderman, Piet W, Hogervorst, Frans

“…Adhesion of platelets to the subendothelial matrix of an injured vessel wall is an essential step in triggering the formation of a haemostatic plug…”
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Glycoproteins V and Ib-IX form a noncovalent complex in the platelet membrane by Modderman, P W, Admiraal, L G, Sonnenberg, A, von dem Borne, A E

“…Platelet glycoprotein (GP) V is a Mr 82,000 plasma membrane protein of unknown function that is cleaved by the potent platelet agonist, thrombin, to yield a Mr…”
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P-selectin mediates Ca(2+)-dependent adhesion of activated platelets to many different types of leukocytes: detection by flow cytometry by de Bruijne-Admiraal, L G, Modderman, P W, Von dem Borne, A E, Sonnenberg, A

“…Previous studies have shown that thrombin-activated platelets interact through the P-selectin with neutrophils and monocytes. To identify other types of…”
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Detection of platelet activation with monoclonal antibodies and flow cytometry. Changes during platelet storage by Fijnheer, R, Modderman, P W, Veldman, H, Ouwehand, W H, Nieuwenhuis, H K, Roos, D, de Korte, D

“…To investigate whether changes in platelet condition during platelet storage correlate with an altered expression of platelet membrane proteins, the binding of…”
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Identification of a homozygous single base pair deletion in the gene coding for the human platelet glycoprotein Ib alpha causing Bernard-Soulier syndrome by Simsek, S, Admiraal, L G, Modderman, P W, van der Schoot, C E, von dem Borne, A E

“…Bernard-Soulier Syndrome (BSS) is a hereditary bleeding disorder which is caused by the absence or the dysfunction of the platelet glycoprotein Ib/IX/V (GP…”
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Integrin Recognition of Different Cell-Binding Fragments of Laminin (P1, E3, E8) and Evidence That α6β1 but Not α6β4 Functions as a Major Receptor for Fragment E8 by Sonnenberg, A., Linders, C. J. T., Modderman, P. W., Damsky, C. H., Aumailley, M., Timpl, R.

“…The involvement of integrins in mediating interaction of cells to well-characterized proteolytic fragments (P1, E3, and E8) of laminin was assessed by antibody…”
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In vitro effect of plasmin on human platelet function in plasma : inhibition of aggregation caused by fibrinogenolysis by GOUIN, I, LESCOMPTE, T, MOREL, M.-C, LEBRAZI, J, MODDERMAN, P. W, KAPLAN, C, SAMAMA, M. M

“…Plasmin has been reported both to activate platelets and to inhibit platelet functions. The latter effect was thought to be caused by proteolysis of the main…”
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Human Vascular Endothelial Cells Express a Membrane Protein Complex Immunochemically Indistinguishable From the Platelet VLA-2 (Glycoprotein Ia-IIa) Complex by Giltay, Jacques C., Brinkman, Herm-Jan M., Modderman, Piet W., Kr. von dem Borne, Albert E.G., van Mourik, Jan A.

“…Endothelial cells express surface molecules that are involved in cell-matrix interaction, including the vitronectin receptor and the fibronectin receptor, both…”
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Integrin recognition of different cell-binding fragments of laminin (P1, E3, E8) and evidence that alpha 6 beta 1 but not alpha 6 beta 4 functions as a major receptor for fragment E8 by Sonnenberg, A, Linders, C J, Modderman, P W, Damsky, C H, Aumailley, M, Timpl, R

“…The involvement of integrins in mediating interaction of cells to well-characterized proteolytic fragments (P1, E3, and E8) of laminin was assessed by antibody…”
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A monoclonal antibody to the human platelet glycoprotein IIb/IIIa complex induces platelet activation by Modderman, P W, Huisman, H G, van Mourik, J A, von dem Borne, A E

“…The platelet glycoprotein (GP) IIb/IIIa complex functions as the receptor for fibrinogen on activated platelets. The effects of two anti-GPIIb/IIIa monoclonal…”
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Detection of circulating human platelet fragments by using monoclonal antibodies against platelet glycoprotein IIb-IIIa complex by Vos, J J, Huisman, J G, Modderman, P W, von dem Borne, A E

“…A radioimmunoassay (RIA) for the detection of platelets and platelet fragments was developed. A sandwich of two monoclonal antibodies directed against the…”
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P-Selectin Mediates Ca2+-Dependent Adhesion of Activated Platelets to Many Different Types of Leukocytes: Detection by Flow Cytometry by de Bruijne-Admiraal, Lucia G., Modderman, Piet W., E.G.Kr, Albert, Borne, Von dem, Sonnenberg, Arnoud

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Substitution of Pichia pastoris-derived recombinant proteins with mannose containing O- and N-linked glycans decreases specificity of diagnostic tests by van Oort, Erica, Lerouge, Patrice, de Heer, Pleuni G, Séveno, Martial, Coquet, Laurent, Modderman, Piet W, Faye, Loïc, Aalberse, Rob C, van Ree, Ronald

“…Recombinant proteins from Pichia pastoris need to be fully evaluated before used as diagnostic tools. The objective of this study was to investigate whether…”
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The platelet alloantigen Zwa or PlA1 is expressed by cultured endothelial cells by Leeksma, O C, Giltay, J C, Zandbergen-Spaargaren, J, Modderman, P W, van Mourik, J A, von dem Borne, A E

“…Recently, the synthesis by cultured human endothelial cells of a membrane protein complex immunologically related to platelet glycoprotein (GP) IIb/IIIa…”
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Decreased stability and structural heterogeneity of the residual platelet glycoprotein IIb/IIIa complex in a variant of Glanzmann's thrombasthenia by Modderman, P W, van Mourik, J A, van Berkel, W, Cordell, J L, Morel, M C, Kaplan, C, Ouwehand, W H, Huisman, J G, von dem Borne, A E

“…A patient is described with a disturbance of platelet function comparable to that in Glanzmann's thrombasthenia. Platelet aggregation and binding of fibrinogen…”
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Determinants in the cytoplasmic domain of P-selectin required for sorting to secretory granules by Modderman, P W, Beuling, E A, Govers, L A, Calafat, J, Janssen, H, Von dem Borne, A E, Sonnenberg, A

“…P-selectin is a granule membrane protein of platelets and endothelial cells that is expressed at the plasma membrane after cell activation. To determine which…”
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Tyrosine phosphorylation of P-selectin in intact platelets and in a disulphide-linked complex with immunoprecipitated pp60c-src by MODDERMAN, P. W, VON DEM BORNE, A. E. G. K, SONNENBERG, A

“…P-selectin is a 140 kDa membrane glycoprotein found in secretory granules of platelets and endothelial cells where it is rapidly translocated to the plasma…”
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Human vascular endothelial cells express a membrane protein complex immunochemically indistinguishable from the platelet VLA-2 (glycoprotein Ia-IIa) complex by Giltay, JC, Brinkman, HJ, Modderman, PW, von dem Borne, AE, van Mourik, JA

“…Endothelial cells express surface molecules that are involved in cell- matrix interaction, including the vitronectin receptor and the fibronectin receptor,…”
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Glycoproteins IIb and IIIa in K562 cells [letter] by Giltay, JC, Brinkman, HJ, Modderman, PW, Tetteroo, PA, van Mourik, JA

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Glycoproteins IIb and IIIa in K562 cells by Giltay, J C, Brinkman, H J, Modderman, P W, Tetteroo, P A, van Mourik, J A

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