Search Results - "Mockel, Martin"
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Cleavage of cohesin rings coordinates the separation of centrioles and chromatids
Published in Nature cell biology (01-08-2011)“…Cohesin pairs sister chromatids by forming a tripartite Scc1-Smc1-Smc3 ring around them. In mitosis, cohesin is removed from chromosome arms by the…”
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IFCC educational materials on selected analytical and clinical applications of high sensitivity cardiac troponin assays
Published in Clinical biochemistry (01-03-2015)“…In 2011, the IFCC Task Force on Clinical Applications of Cardiac Bio-Markers (TF-CB) was formed, with the purpose of providing evidence based educational…”
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ESC Study Group on Cardiac Biomarkers of the Association for Acute CardioVascular Care: A fond farewell at the retirement of CKMB
Published in European heart journal (14-06-2021)Get full text
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Management of major bleeding for anticoagulated patients in the Emergency Department: an European experts consensus statement
Published in European journal of emergency medicine (01-10-2023)“…An increasing number of patients presenting to the emergency department (ED) with life-threatening bleeding are using oral anticoagulants, such as warfarin,…”
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Diagnostic Performance of Procalcitonin for the Early Identification of Sepsis in Patients with Elevated qSOFA Score at Emergency Admission
Published in Journal of clinical medicine (28-08-2021)“…Infectious biomarkers such as procalcitonin (PCT) can help overcome the lack of sensitivity of the quick Sequential Organ Failure Assessment (qSOFA) score for…”
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Physicians' attitudes towards smartphone-based emergency response communities for anaphylaxis: Survey
Published in Health policy and technology (01-03-2022)“…•Positive attitudes towards an emergency response communities for anaphylaxis (AERC).•High willingness among physicians to provide advice to join an AERC was…”
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Coma of unknown origin in the emergency department: implementation of an in-house management routine
Published in Scandinavian journal of trauma, resuscitation and emergency medicine (27-04-2016)“…Coma of unknown origin is an emergency caused by a variety of possibly life-threatening pathologies. Although lethality is high, there are currently no…”
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Heparin Strongly Induces Soluble Fms-Like Tyrosine Kinase 1 Release In Vivo and In Vitro—Brief Report
Published in Arteriosclerosis, thrombosis, and vascular biology (01-12-2011)“…OBJECTIVE—Soluble fms-like tyrosine kinase 1 (sFlt1) is involved in the pathophysiology of preeclampsia and coronary artery disease. Because sFlt1 has a…”
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Serial Changes in Highly Sensitive Troponin I Assay and Early Diagnosis of Myocardial Infarction
Published in JAMA : the journal of the American Medical Association (28-12-2011)“…CONTEXT Introduction of highly sensitive troponin assays into clinical practice has substantially improved the evaluation of patients with chest pain…”
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R-loop proximity proteomics identifies a role of DDX41 in transcription-associated genomic instability
Published in Nature communications (16-12-2021)“…Transcription poses a threat to genomic stability through the formation of R-loops that can obstruct progression of replication forks. R-loops are…”
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Ythdf is a N6‐methyladenosine reader that modulates Fmr1 target mRNA selection and restricts axonal growth in Drosophila
Published in The EMBO journal (15-02-2021)“…N6‐methyladenosine (m 6 A) regulates a variety of physiological processes through modulation of RNA metabolism. This modification is particularly enriched in…”
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Modelling variations of emergency attendances using data on community mobility, climate and air pollution
Published in Scientific reports (23-11-2023)“…Air pollution is associated with morbidity and mortality worldwide. We investigated the impact of improved air quality during the economic lockdown during the…”
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E-scooter incidents in Berlin: an evaluation of risk factors and injury patterns
Published in Emergency medicine journal : EMJ (01-04-2022)“…E-scooters have emerged as a frequently used vehicle in German cities due to their high availability and easy access. However, investigations about the causes…”
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Paclitaxel-Eluting Stents versus Bare-Metal Stents in Acute Myocardial Infarction
Published in The New England journal of medicine (07-05-2009)“…Acute ST-segment elevation myocardial infarction is often treated with immediate coronary stenting of the infarct-related artery. The use of a…”
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Early discharge using single cardiac troponin and copeptin testing in patients with suspected acute coronary syndrome (ACS): a randomized, controlled clinical process study
Published in European heart journal (07-02-2015)“…This randomized controlled trial (RCT) evaluated whether a process with single combined testing of copeptin and troponin at admission in patients with…”
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Novel Biomarkers Early Predict the Severity of Acute Kidney Injury After Cardiac Surgery in Adults
Published in The Annals of thoracic surgery (01-07-2009)“…Background The purpose of this study was to investigate the ability of neutrophil gelatinase-associated lipocalin (NGAL), cystatin C, and their combination in…”
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Structural basis of human kinesin-8 function and inhibition
Published in Proceedings of the National Academy of Sciences - PNAS (07-11-2017)“…Kinesin motors play diverse roles in mitosis and are targets for antimitotic drugs. The clinical significance of these motors emphasizes the importance of…”
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Linking CRISPR-Cas9 double-strand break profiles to gene editing precision with BreakTag
Published in Nature biotechnology (13-05-2024)“…Cas9 can cleave DNA in both blunt and staggered configurations, resulting in distinct editing outcomes, but what dictates the type of Cas9 incisions is largely…”
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Self-referred walk-in patients in the emergency department - who and why? Consultation determinants in a multicenter study of respiratory patients in Berlin, Germany
Published in BMC health services research (10-09-2020)“…Emergency department (ED) consultations are on the rise, and frequently consultations by non-urgent patients have been held accountable. Self-referred walk-in…”
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