Search Results - "Mock, DM"

Randomized Trial of Liberal Versus Restrictive Guidelines for Red Blood Cell Transfusion in Preterm Infants by Bell, Edward F, Strauss, Ronald G, Widness, John A, Mahoney, Larry T, Mock, Donald M, Seward, Victoria J, Cress, Gretchen A, Johnson, Karen J, Kromer, Irma J, Zimmerman, M. Bridget

“…Although many centers have introduced more restrictive transfusion policies for preterm infants in recent years, the benefits and adverse consequences of…”
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Increased urinary excretion of 3-hydroxyisovaleric acid and decreased urinary excretion of biotin are sensitive early indicators of decreased biotin status in experimental biotin deficiency by Mock, NI, Malik, MI, Stumbo, PJ, Bishop, WP, Mock, DM

“…To assess the utility of various indicators of biotin status, marginal biotin deficiency was induced experimentally in normal adults. Ten subjects consumed a…”
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Marginal biotin deficiency is teratogenic in mice and perhaps humans: a review of biotin deficiency during human pregnancy and effects of biotin deficiency on gene expression and enzyme activities in mouse dam and fetus by Mock, Donald M.

“…Recent studies of biotin status during pregnancy provide evidence that a marginal degree of biotin deficiency develops in a substantial proportion of women…”
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Marginal biotin deficiency during normal pregnancy by MOCK, Donald M, QUIRK, J. Gerald, MOCK, Nell I

“…Biotin deficiency is teratogenic in several mammalian species. Approximately 50% of pregnant women have an abnormally increased urinary excretion of…”
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Biotin biochemistry and human requirements by Zempleni, Janos, Mock, DonaldM

“…Human biotin turnover and requirements can be estimated on the basis of (1) concentrations of biotin and metabolites in body fluids, (2) activities of…”
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Determination of the biotin content of select foods using accurate and sensitive HPLC/avidin binding by Staggs, C.G., Sealey, W.M., McCabe, B.J., Teague, A.M., Mock, D.M.

“…Assessing dietary biotin content, biotin bioavailability, and resulting biotin status are crucial in determining whether biotin deficiency is teratogenic in…”
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Marginal biotin deficiency is teratogenic in ICR mice by Mock, Donald M, Mock, Nell I, Stewart, Christopher W, LaBorde, James B, Hansen, Deborah K

“…The incidence of marginal biotin deficiency in normal human gestation is approximately one in three. In ICR mice, maternal biotin deficiency results in cleft…”
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Circulating RBC volume, measured with biotinylated RBCs, is superior to the Hct to document the hematologic effects of delayed versus immediate umbilical cord clamping in preterm neonates by Strauss, Ronald G., Mock, Donald M., Johnson, Karen, Mock, Nell I., Cress, Gretchen, Knosp, Laura, Lobas, Lori, Schmidt, Robert L.

“…BACKGROUND: One problem assessing the hematologic physiology of preterm infants after delivery and/or the efficacy and toxicity of therapeutic interventions…”
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Indicators of marginal biotin deficiency and repletion in humans: validation of 3-hydroxyisovaleric acid excretion and a leucine challenge by MOCK, Donald M, HENRICH, Cindy L, CARNELL, Nadine, MOCK, Nell I

“…The results of clinical studies have provided evidence that marginal biotin deficiency is more common than was previously thought. A previous study of 10…”
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Biotin deficiency reduces expression of SLC19A3, a potential biotin transporter, in leukocytes from human blood by Vlasova, Tatyana I, Stratton, Shawna L, Wells, Amanda M, Mock, Nell I, Mock, Donald M

“…In evaluating potential indicators of biotin status, we quantitated the expression of biotin-related genes in leukocytes from human blood of normal subjects…”
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Uptake and metabolism of biotin by human peripheral blood mononuclear cells by Zempleni, J, Mock, D M

“…We studied the uptake of biotin into human peripheral blood mononuclear cells (PBMC) using [3H]biotin and studied the catabolism of biotin in PBMC using…”
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Determinations of biotin in biological fluids by Mock, D M

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Smoking accelerates biotin catabolism in women by Sealey, W.M, Teague, A.M, Stratton, S.L, Mock, D.M

“…Background: Smoking accelerates the degradation of many nutrients, including lipids, antioxidants, and certain B vitamins. Accelerated biotin catabolism is of…”
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Marginal maternal biotin deficiency in CD-1 mice reduces fetal mass of biotin-dependent carboxylases by Sealey, Wendy M, Stratton, Shawna L, Mock, Donald M, Hansen, Deborah K

“…Marginal maternal biotin deficiency reduces hepatic activity of biotin-dependent carboxylases and causes high rates of fetal birth defects in mice. We tested…”
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Lymphocyte propionyl-CoA carboxylase is an early and sensitive indicator of biotin deficiency in rats, but urinary excretion of 3-hydroxypropionic acid is not by Mock, Donald M, Mock, Nell I

“…Recent clinical studies have provided evidence that marginal biotin deficiency is more common than previously thought. The validity of that conclusion rests on…”
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Coordinately increased lysozymuria and lysosomal enzymuria induced by maleic acid by Al-Bander, Hamoudi A., Mock, Donald M., Etheredge, Stephen B., Paukert, Thomas T., Humphreys, Michael H., Morris, R. Curtis

“…Coordinately increased lysozymuria and lysosomal enzymuria induced by maleic acid. During the acute renal tubular dysfunction of Fanconi syndrome and type 2…”
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In vivo biotin supplementation at a pharmacologic dose decreases proliferation rates of human peripheral blood mononuclear cells and cytokine release by Zempleni, J, Helm, R M, Mock, D M

“…Theoretically, vitamin supplements may either enhance or reduce protein synthesis and proliferation in peripheral blood mononuclear cells (PBMC). In the…”
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Instability of the biotin–protein bond in human plasma by Bogusiewicz, Anna, Mock, Nell I, Mock, Donald M

“…Labeling proteins with biotin offers an alternative to labeling with radioisotopes for pharmacokinetic studies in humans. However, stability of the…”
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Posttransfusion 24-hour recovery and subsequent survival of allogeneic red blood cells in the bloodstream of newborn infants by Strauss, Ronald G., Mock, Donald M., Widness, John A., Johnson, Karen, Cress, Gretchen, Schmidt, Robert L.

“…BACKGROUND:  The feasibility, efficacy, and safety of transfusing stored allogeneic RBCs has been demon‐strated for small‐volume transfusions given to infants…”
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Biotin status: which are valid indicators and how do we know? by Mock, D M

“…Although estimated average requirements for biotin have been proposed, the human requirements for biotin in specific populations and at various ages remain…”
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