Search Results - "Mochizuki, Kota"
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The ASCT/SCS cycle fuels mitochondrial ATP and acetate production in Trypanosoma brucei
Published in Biochimica et biophysica acta. Bioenergetics (01-11-2020)“…Acetate:succinate CoA transferase (ASCT) is a mitochondrial enzyme that catalyzes the production of acetate and succinyl-CoA, which is coupled to ATP…”
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Identification of 3,4-Dihydro-2H,6H-pyrimido[1,2-c][1,3]benzothiazin-6-imine Derivatives as Novel Selective Inhibitors of Plasmodium falciparum Dihydroorotate Dehydrogenase
Published in International journal of molecular sciences (05-07-2021)“…Plasmodium falciparum’s resistance to available antimalarial drugs highlights the need for the development of novel drugs. Pyrimidine de novo biosynthesis is a…”
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3
IL-17A, a possible biomarker for the evaluation of treatment response in Trypanosoma cruzi infected children: A 12-months follow-up study in Bolivia
Published in PLoS neglected tropical diseases (25-09-2019)“…The National Program for Chagas disease was implemented in Bolivia in 2006, and it greatly decreased the number of infections through vector control…”
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Use of Corticosteroids for Urinary Tuberculosis Patients at Risk of Developing Ureteral Obstruction
Published in Internal Medicine (01-01-2016)“…A 77-year-old man with urinary tuberculosis developed post renal anuria two days after starting an anti-tuberculosis drug regimen. He had bilateral…”
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5
Monotherapy with a novel intervenolin derivative, AS‐1934, is an effective treatment for Helicobacter pylori infection
Published in Helicobacter (Cambridge, Mass.) (01-04-2018)“…Background Helicobacter pylori (H. pylori) infection causes various gastrointestinal diseases including gastric cancer. Hence, eradication of this infection…”
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Identification of 3,4-Dihydro-2 H ,6 H -pyrimido[1,2- c ][1,3]benzothiazin-6-imine Derivatives as Novel Selective Inhibitors of Plasmodium falciparum Dihydroorotate Dehydrogenase
Published in International journal of molecular sciences (05-07-2021)“…'s resistance to available antimalarial drugs highlights the need for the development of novel drugs. Pyrimidine de novo biosynthesis is a validated drug…”
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Journal Article