Search Results - "Mochel, J."

Population Pharmacokinetics and Absolute Oral Bioavailability of Lasalocid after Single Intravenous and Intracrop Administration in Laying Hens by Bello, A., Mochel, J. P., Jajor, P., Bobrek, K., Świtała, M., Poźniak, B.

“…Lasalocid sodium is a polyether carboxylic ionophore agent authorized by the EU for use as a coccidiostat in broilers, turkeys, and pullets up to 16 weeks of…”
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Mathematical modeling and simulation in animal health - Part II: principles, methods, applications, and value of physiologically based pharmacokinetic modeling in veterinary medicine and food safety assessment by Lin, Z., Gehring, R., Mochel, J. P., Lavé, T., Riviere, J. E.

“…This review provides a tutorial for individuals interested in quantitative veterinary pharmacology and toxicology and offers a basis for establishing…”
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Mathematical modeling and simulation in animal health. Part III: Using nonlinear mixed‐effects to characterize and quantify variability in drug pharmacokinetics by Bon, C., Toutain, P. L., Concordet, D., Gehring, R., Martin‐Jimenez, T., Smith, J., Pelligand, L., Martinez, M., Whittem, T., Riviere, J. E., Mochel, J. P.

“…A common feature of human and veterinary pharmacokinetics is the importance of identifying and quantifying the key determinants of between‐patient variability…”
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Serum vitamin B 12 and related 5-methyltetrahydrofolate-homocysteine methyltransferase reductase and cubilin genotypes predict neural outcomes across the Alzheimer's disease spectrum by McLimans, K E, Collazo Martinez, A D, Mochel, J P, Allenspach, K, Willette, A A

“…Epidemiological studies show mixed findings for serum vitamin B (B ) and both cognitive and regional volume outcomes. No studies to date have comprehensively…”
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Serum vitamin B12 and related 5-methyltetrahydrofolate-homocysteine methyltransferase reductase and cubilin genotypes predict neural outcomes across the Alzheimerʼs disease spectrum by McLimans, K. E., Collazo Martinez, A. D., Mochel, J. P., Allenspach, K., Willette, A. A.

“…Epidemiological studies show mixed findings for serum vitamin B12 (B12) and both cognitive and regional volume outcomes. No studies to date have…”
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Pharmacokinetics of fentanyl citrate and norfentanyl in Holstein calves and effect of analytical performances on fentanyl parameter estimation by Smith, J. S., Coetzee, J. F., Fisher, I. W. G., Borts, D. J., Mochel, J. P.

“…This study describes the pharmacokinetics of intravenously administered (i.v.) fentanyl citrate, and its primary metabolite norfentanyl in Holstein calves…”
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Modeling of Large Pharmacokinetic Data Using Nonlinear Mixed‐Effects: A Paradigm Shift in Veterinary Pharmacology. A Case Study With Robenacoxib in Cats by Pelligand, L, Soubret, A, King, JN, Elliott, J, Mochel, JP

“…The objective of this study was to model the pharmacokinetics (PKs) of robenacoxib in cats using a nonlinear mixed‐effects (NLME) approach, leveraging all…”
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Effects of the estrous cycle and pregnancy status on cardiovascular variables in healthy bitches by Ward, J., Mochel, J.P., Seo, Y.-J., Sathe, S.

“…The aim of the study was to characterize changes in maternal cardiovascular variables throughout the reproductive cycle in healthy bitches and determine…”
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Mathematical modeling and simulation in animal health. Part I: Moving beyond pharmacokinetics by Riviere, J.E., Gabrielsson, J., Fink, M., Mochel, J.

“…The application of mathematical modeling to problems in animal health has a rich history in the form of pharmacokinetic modeling applied to problems in…”
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Echocardiographic caudal vena cava measurements in healthy cats and in cats with congestive heart failure and non-cardiac causes of cavitary effusions by Barron, L.Z., DeFrancesco, T.C., Chou, Y.-Y., Bonagura, J.D., Tropf, M.A., Murphy, S.D., McManamey, A.K., Yuan, L., Mochel, J.P., Ward, J.L.

“…Echocardiographic indices of the inferior vena cava have been associated with elevated right atrial pressures in humans. Describe caudal vena caval (CVC)…”
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Comparison of milk and plasma pharmacokinetics of meloxicam in postpartum versus mid‐lactation Holstein cows by Gorden, P. J., Burchard, M., Ydstie, J. A., Kleinhenz, M. D., Wulf, L. W., Rajewski, S. J., Wang, C., Gehring, R., Mochel, J. P., Coetzee, J. F.

“…The objective of this study reported here was determine whether differences occurred in meloxicam pharmacokinetics between postpartum cows and mid‐lactation…”
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Multiple comparison procedure and modeling: a versatile tool for evaluating dose-response relationships in veterinary pharmacology - a case study with furosemide by Bieth, B., Bornkamp, B., Toutain, C., Garcia, R., Mochel, J. P.

“…Congestive heart failure (CHF) is a leading cause of mortality with an increasing prevalence in human and canine populations. While furosemide is a loop…”
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Population pharmacokinetic analysis of blood concentrations of robenacoxib in dogs with osteoarthritis by Fink, M., Letellier, I., Peyrou, M., Mochel, J.P., Jung, M., King, J.N., Gruet, P., Giraudel, J.M.

“…The purpose of this analysis was to investigate whether the recommended daily dosage of 1–2mg/kg robenacoxib provides consistent exposure when administered to…”
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Network on veterinary medicines initiated by the European Federation For Pharmaceutical Sciences by Mochel, J. P., Tyden, E., Hellmann, K., Vendrig, J. C., Şenel, S., Dencker, L., Cristina, R. T., Linden, H., Schmerold, I.

“…The European Federation for Pharmaceutical Sciences (EUFEPS) was founded 25 years ago by more than 20 national pharmaceutical societies and faculty members. As…”
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Capturing the dynamics of systemic Renin-Angiotensin-Aldosterone System (RAAS) peptides heightens the understanding of the effect of benazepril in dogs by MOCHEL, J. P., PEYROU, M., FINK, M., STREHLAU, G., MOHAMED, R., GIRAUDEL, J. M., PLOEGER, B., DANHOF, M.

“…Mochel, J. P., Peyrou, M, Fink, M, Strehlau, G, Mohamed, R, Giraudel, J. M., Ploeger, B, Danhof, M. Capturing the dynamics of systemic…”
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Thermodynamics of melting and freezing in small particles by Vanfleet, Richard R., Mochel, J.M.

“…The properties of small particles can be markedly different from the bulk. A classical thermodynamic treatment of the melting and freezing of small particles,…”
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Animal Health Modeling & Simulation Society: a new society promoting model-based approaches in veterinary pharmacology by Mochel, J. P., Gabrielsson, J., Collard, W., Fink, M., Gehring, R., Laffont, C., Liu, Y., Martin-Jimenez, T., Pelligand, L., Steimer, J.-L., Toutain, P.-L., Whittem, T., Riviere, J.

“…The Animal Health Modeling & Simulation Society (AHM&S) is a newly founded association (2012) that aims to promote the development, application, and…”
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Better Nutrition, Better Care: An Initiative to Improve Early Identification and Intervention of Malnutrition in Pediatric Oncology and BMT Patients by Huddle, C., Hirsch, H., Kasay, C., Beverley, M., Mochel, J., Clark, E., Sharry, B.

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Response to letter from Atkins et al. Capturing the dynamics of systemic Renin-Angiotensin-Aldosterone System (RAAS) peptides heightens the understanding of the effect of benazepril in dogs by Mochel, J., Fink, M.

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Atomically thin superfluid helium films on solid hydrogen by SHIRRON, P. J, MOCHEL, J. M

“…We have measured both adsorption isotherms and third-sound resonance of atomically thin {sup 4}He films on solid hydrogen. We find helium more weakly bound to…”
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