Search Results - "Mochan, Ericka"

Age-Related Changes to the Immune System Exacerbate the Inflammatory Response to Pandemic H1N1 Infection by Mochan, Ericka, Sego, T. J., Ermentrout, Bard

“…Age-induced dysregulation of the immune response is a major contributor to the morbidity and mortality related to influenza a virus infections. Experimental…”
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Compartmental Model Suggests Importance of Innate Immune Response to COVID-19 Infection in Rhesus Macaques by Mochan, Ericka, Sego, T. J., Gaona, Lauren, Rial, Emmaline, Ermentrout, G. Bard

“…The pandemic outbreak of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has quickly spread worldwide, creating a serious health crisis. The virus…”
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A multiscale multicellular spatiotemporal model of local influenza infection and immune response by Sego, T.J., Mochan, Ericka D., Ermentrout, G. Bard, Glazier, James A.

“…•Developed a multiscale, multicellular spatiotemporal model of influenza infection and immune response.•Model is partially generated from a calibrated…”
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Mathematical Modeling of the Lethal Synergism of Coinfecting Pathogens in Respiratory Viral Infections: A Review by Mochan, Ericka, Sego, T J

“…Influenza A virus (IAV) infections represent a substantial global health challenge and are often accompanied by coinfections involving secondary viruses or…”
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A Three-Tiered Study of Differences in Murine Intrahost Immune Response to Multiple Pneumococcal Strains by Mochan-Keef, Ericka, Swigon, David, Ermentrout, G Bard, Clermont, Gilles

“…We apply a previously developed 4-variable ordinary differential equation model of in-host immune response to pneumococcal pneumonia to study the variability…”
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The inflammatory response to influenza A virus (H1N1): An experimental and mathematical study by Price, Ian, Mochan-Keef, Ericka D, Swigon, David, Ermentrout, G Bard, Lukens, Sarah, Toapanta, Franklin R, Ross, Ted M, Clermont, Gilles

“…Mortality from influenza infections continues as a global public health issue, with the host inflammatory response contributing to fatalities related to the…”
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TREAP: A New Topological Approach to Drug Target Inference by Wang, Muying, Luciani, Lauren L., Noh, Heeju, Mochan, Ericka, Shoemaker, Jason E.

“…Over 50% of drugs fail in stage 3 clinical trials, many because of a poor understanding of the drug’s mechanisms of action (MoA). A better comprehension of…”
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A mathematical model of intrahost pneumococcal pneumonia infection dynamics in murine strains by Mochan, Ericka, Swigon, David, Ermentrout, G. Bard, Lukens, Sarah, Clermont, Gilles

“…The seriousness of pneumococcal pneumonia in mouse models has been shown to depend both on bacterial serotype and murine strain. We here present a simple…”
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A large-scale immuno-epidemiological simulation of influenza A epidemics by Lukens, Sarah, DePasse, Jay, Rosenfeld, Roni, Ghedin, Elodie, Mochan, Ericka, Brown, Shawn T, Grefenstette, John, Burke, Donald S, Swigon, David, Clermont, Gilles

“…Agent based models (ABM) are useful to explore population-level scenarios of disease spread and containment, but typically characterize infected individuals…”
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990: USING BIOMARKERS TO ENHANCE 60-DAY IN HOSPITAL MORTALITY PREDICTION FOR EARLY SEPSIS PATIENT by Zhu, Li, Clermont, Gilles, Zhang, Li Ang, Mochan-Keef, Ericka, Parker, Robert, Swigon, David, Pike, Francis

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442: DISCRETE DYNAMICAL MODELING OF INFLUENZA INFECTION SUGGESTS AGE-DEPENDENT DIFFERENCES IN IMMUNITY by Mochan-Keef, Ericka, Urbano, Alisa, Swigon, David, Ermentrout, G Bard, Parker, Robert, Clermont, Gilles

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A Three-Tiered Study of Differences in Murine Intrahost Immune Response to Multiple Pneumococcal Strains: e0134012 by Mochan-Keef, Ericka, Swigon, David, Ermentrout, G Bard, Clermont, Gilles

“…We apply a previously developed 4-variable ordinary differential equation model of in-host immune response to pneumococcal pneumonia to study the variability…”
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Training device for a double-opposing Z-plasty for cleft palate repair by Mochan, E, Gettens, R T T, Stoddard, P

“…Cleft palate occurs in one in every 600 births worldwide. The standard method for repairing cleft palate is the double-opposing Z-plasty. This surgery is…”
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