Search Results - "Mochalkin, I"

Refine Results
  1. 1

    A Model of Fibrin Formation Based on Crystal Structures of Fibrinogen and Fibrin Fragments Complexed with Synthetic Peptides by Yang, Z, Mochalkin, I, Doolittle, R F

    “…A blood clot is a meshwork of fibrin fibers built up by the systematic assembly of fibrinogen molecules proteolyzed by thrombin. Here, we describe a model of…”
    Get full text
    Journal Article
  2. 2

    Crystal structure of native chicken fibrinogen at 5.5-Å resolution by Yang, Z, Mochalkin, I, Veerapandian, L, Riley, M, Doolittle, R F

    “…The crystal structure of native chicken fibrinogen has been determined at a resolution of 5.5 Å. The full-length molecule is 460 Å in length and sigmoidally…”
    Get full text
    Journal Article
  3. 3

    Structure and binding determinants of the recombinant kringle-2 domain of human plasminogen to an internal peptide from a group A Streptococcal surface protein by Rios-Steiner, J L, Schenone, M, Mochalkin, I, Tulinsky, A, Castellino, F J

    Published in Journal of molecular biology (11-05-2001)
    “…The X-ray crystal structure of a complex of a modified recombinant kringle-2 domain of human plasminogen, K2Pg[C4G/E56D/L72Y] (mK2Pg), containing an…”
    Get full text
    Journal Article
  4. 4

    Crystal Structure Studies on Fibrinogen and Fibrin by DOOLITTLE, RUSSELL F., YANG, ZHE, MOCHALKIN, IGOR

    Published in Annals of the New York Academy of Sciences (01-01-2001)
    “…: X‐ray crystallography studies on fragments D and double‐D from human fibrinogen and fibrin have revealed the details of knob‐hole interactions between fibrin…”
    Get full text
    Journal Article
  5. 5

    Structure and Ligand Binding Determinants of the Recombinant Kringle 5 Domain of Human Plasminogen by Chang, Yuan, Mochalkin, Igor, McCance, Stephen G, Cheng, Beisong, Tulinsky, Alexander, Castellino, Francis J

    Published in Biochemistry (Easton) (10-03-1998)
    “…The X-ray crystal structure of the recombinant (r) kringle 5 domain of human plasminogen (K5HPg) has been solved by molecular replacement methods using K1HPg…”
    Get full text
    Journal Article
  6. 6

    Structure of thrombin complexed with selective non-electrophilic inhibitors having cyclohexyl moieties at P1 by Krishnan, Raman, Mochalkin, Igor, Arni, Raghuvir, Tulinsky, A.

    “…The crystal structures of five new non‐electrophilic β‐strand‐templated thrombin active‐site inhibitors have been determined bound to the enzyme. Four…”
    Get full text
    Journal Article
  7. 7

    Recombinant Kringle IV-10 Modules of Human Apolipoprotein(a):  Structure, Ligand Binding Modes, and Biological Relevance by Mochalkin, Igor, Cheng, Beisong, Klezovitch, Olga, Scanu, Angelo M, Tulinsky, Alexander

    Published in Biochemistry (Easton) (16-02-1999)
    “…The kringle modules of apolipoprotein(a) [apo(a)] of lipoprotein(a) [Lp(a)] are highly homologous with kringle 4 of plasminogen (75−94%) and like the latter…”
    Get full text
    Journal Article
  8. 8
  9. 9

    Structures of thrombin retro-inhibited with SEL2711 and SEL2770 as they relate to factor Xa binding by Mochalkin, Igor, Tulinsky, A.

    “…Most thrombin active‐site inhibitors form a short antiparallel β‐strand with residues Ser214–Gly216. However, the Selectide Corp. inhibitors SEL2711 and…”
    Get full text
    Journal Article
  10. 10
  11. 11
  12. 12
  13. 13
  14. 14
  15. 15
  16. 16
  17. 17
  18. 18
  19. 19
  20. 20