Search Results - "Moawadh, Mamdoh S"

Molecular Evaluation of the Impact of Polymorphic Variants in Apoptotic ( Bcl-2/Bax ) and Proinflammatory Cytokine ( TNF-α/IL-8 ) Genes on the Susceptibility and Progression of Myeloproliferative Neoplasms: A Case-Control Biomarker Study by Moawadh, Mamdoh S, Mir, Rashid, Tayeb, Faris J, Asim, Orooba, Ullah, Mohammad Fahad

“…The regulation of apoptosis (the programmed cell death) is dependent on the crucial involvement of BCL2 and BAX. The and polymorphic variations in the promoter…”
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Potential honey bee (Apis mellifera) allergens associated with IgE-mediated allergy- An In-silico study by Sadaf Anwar, Mohd Adnan Kausar, Halah Salah Mohammed Abdalaziz, Halima Mustafa Elagib, Mamdoh S. Moawadh, Rajeev Singh, Lovnish Thakur, Subhabrata Kar, Mohammad Zeeshsan Najm, Mohd Saeed, Fawaz Ahmed Alrobah, Abdullah Nashmi AlRashidi, Mohnad Abdalla

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Investigation of the Protective Effects of Urtica dioica, Capsella bursa-pastoris and Inula racemosa on Acetaminophen-Induced Nephrotoxicity in Swiss Albino Male Mice by Yousuf, Sumaira, Shabir, Shabnam, Mehdi, Mohammad Murtaza, Srivastav, Shailesh, Mohammedsaleh, Zuhair M., Bassfar, Zaid, Jalal, Mohammed M., Moawadh, Mamdoh S., Jamous, Yahya F., Singh, Sandeep Kumar, Vamanu, Emanuel, Singh, Mahendra P.

“…Acetaminophen (APAP) is the most commonly used nonprescription antipyretic-analgesic drug. This medication is thought to be safe at the suggested dosage (4…”
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Targeting NF-κB signaling cascades of glioblastoma by a natural benzophenone, garcinol, via in vitro and molecular docking approaches by Rizvi, Syed Mohd Danish, Almazni, Ibrahim A, Moawadh, Mamdoh S, Alharbi, Zeyad M, Helmi, Nawal, Alqahtani, Leena S, Hussain, Talib, Alafnan, Ahmed, Moin, Afrasim, Elkhalifa, AbdElmoneim O, Awadelkareem, Amir Mahgoub, Khalid, Mohammad, Tiwari, Rohit Kumar

“…Glioblastoma multiforme (GBM) is regarded as the most aggressive form of brain tumor delineated by high cellular heterogeneity; it is resistant to conventional…”
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Nutraceutical Effect of Resveratrol on the Mammary Gland: Focusing on the NF-κb /Nrf2 Signaling Pathways by Malik, Muhammad Umair Ul Hassan, Hashmi, Nighat, Khan, Marium, Aabdin, Zain Ul, Sami, Rokayya, Aljahani, Amani H, Al-Eisa, Rasha A, Moawadh, Mamdoh S, Algehainy, Naseh A

“…The aim of this study is to evaluate the defensive role of resveratrol, which is antagonistic to the oxidative stress and inflammation that is prompted by LPS…”
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Association of Genetic and Allelic Variants of Von Willebrand Factor (VWF), Glutathione S-Transferase and Tumor Necrosis Factor Alpha with Ischemic Stroke Susceptibility and Progression in the Saudi Population by Jalal, Mohammed M, Mir, Rashid, Hamadi, Abdullah, Altayar, Malik A, Elfaki, Imadeldin, Barnawi, Jameel, Alkayyal, Almohanad A, Amr, Mouminah, Hadeel, Jabali, Moawadh, Mamdoh S, Alsaedi, Basim S O, Alhelali, Marwan H, Yousif, Aadil

“…Stroke is a key cerebrovascular disease and important cause of death and disability worldwide, including in the kingdom of Saudi Arabia (KSA). It has a large…”
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Enhancing the therapeutic efficacy of Krestin–chitosan nanocomplex for cancer medication via activation of the mitochondrial intrinsic pathway by Albalawi, Karma, Panneerselvam, Chellasamy, Moawadh, Mamdoh S., Alalawy, Adel I., Omran, Awatif M. E., Abdelaziz, Mahmoud A., Mohammedsaleh, Zuhair M., Al-Aoh, Hatem A., Mustafa, Syed Khalid, Keshk, Ali A., Al-Morwani, Majed M., Alessa, Ali Hamzah, Al-Anazi, Menier, Khateeb, Sahar

“…Abstract Surgery, chemotherapy, and radiation therapy are all forms of cancer treatment, as well as more recent methods including interventional radiology and…”
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Molecular docking analysis of natural compounds as TNF-α inhibitors for Crohn's disease management by Moawadh, Mamdoh S

“…Crohn's disease (CD) is a type of inflammatory bowel disease that is immune-mediated and affects the gastrointestinal tract. The chronic and severe nature of…”
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Immunomodulatory effects of Kaempferol on microglial and Macrophage cells during the progression of diabetic retinopathy by Albalawi, Fahad Eid, Alsharif, Ifat, Moawadh, Mamdoh S., Alkhoshaiban, Abdulaziz, Falah Alshehri, Faez, Albalawi, Aishah E, Althobaiti, Norah A., Alharbi, Zeyad M., Almohaimeed, Hailah M.

“…[Display omitted] •Kaempferol attenuates diabetic retinopathy (DR) via targeted inhibition of immune cell responses.•Microglia undergo phenotypic shift,…”
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Computational identification of promising therapeutics via BACE1 Targeting: Implications for Alzheimer's disease by Murad, Hussam Aly Sayed, Moawadh, Mamdoh S, Alzahrani, Abdulrahman, Alkathiri, Ahmad Salah, Almutairi, Abdulrahman, Alhassoun, Madawi Ibrahim, Alniwaider, Rashed Ahmed, Habib, Alaa Hamed, Sain, Ziaullah M, Misbahuddin M Rafeeq

“…Alzheimer's disease (AD) is a significant global healthcare challenge, particularly in the elderly population. This neurodegenerative disorder is characterized…”
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Identification of Novel Genomic Variants in COVID-19 Patients Using Whole-Exome Sequencing: Exploring the Plausible Targets of Functional Genomics by Mir, Rashid, Altemani, Faisal A., Algehainy, Naseh A., Alanazi, Mohammad A., Elfaki, Imadeldin, Alsayed, Badr A., Mir, Mohammad Muzaffar, Mustafa, Syed Khalid, Moawadh, Mamdoh S., Tayeb, Faris J., Alfailfi, Jaber, Alatawi, Sael M., Alhiwety, Mohammed Saad, Ullah, Mohammad Fahad

“…Covid-19 caused by SARS-CoV-2 virus has emerged as an immense burden and an unparalleled global health challenge in recorded human history. The clinical…”
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Identification of potential biomarkers for melanoma cancer (black tumor) using bioinformatics strategy: a study based on GEO and SRA datasets by ALMatrafi, Tahani Ahmad, Mohammedsaleh, Zuhair M., Moawadh, Mamdoh S., Bassfar, Zaid, Jalal, Mohammed M., Badahdah, Fatima Ahmed, Alghamdi, Youssef S., Almasoudi, Hassan Hussain, Hakami, Mohammed Ageeli, Binshaya, Abdulkarim S., Almohaimeed, Hailah M., Soliman, Mona H.

“…Melanoma, a highly invasive type of skin cancer that penetrates the entire dermis layer, is associated with increased mortality rates. Excessive exposure of…”
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Increased NOTCH1 expression is associated with low survival in moderate/ poor differentiated human oral squamous cell carcinoma patients by Mohammedsaleh, Zuhair M., Moawadh, Mamdoh S., Saleh, Fayez M., Jalal, Mohammed M., Al-Otaibi, Abdulaziz S, Saeedi, Nizar H., Baskaran, Rathinasamy, Huang, Chih-Yang, Kumar, V. Bharath

“…Notch deregulation has been reported in various types of cancers, including Oral squamous cell carcinomas (OSCCs). The role of Notch1 signaling in oral…”
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Estimating molecular properties, drug-likeness, cardiotoxic risk, liability profile, and molecular docking study to characterize binding process of key phyto-compounds against serotonin 5-HT2A receptor by Bensaad, Mohamed Sabri, Verma, Devvret, Mitra, Debasis, Helal, Mahmoud, Banjer, Hamsa Jameel, Shami, Ashjan A., Sami, Rokayya, Moawadh, Mamdoh S., Alharbi, Zeyad M., Waggas, Dania S., Baakdah, Fadi, AlHarthi, Siraj B.

“…Nowadays, the physiopathological and molecular mechanisms of multiple diseases have been identified, thus helping scientists to provide a clear answer,…”
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Comprehensive Molecular Evaluation of HNF-1 Alpha, miR-27a, and miR-146 Gene Variants and Their Link with Predisposition and Progression in Type 2 Diabetes Patients by Mir, Rashid, Elfaki, Imadeldin, Elangeeb, M. E, Moawadh, Mamdoh S, Tayeb, Faris Jamal, Barnawi, Jameel, Albalawi, Ibrahim Altedlawi, Alharbi, Amnah A, Alhelali, Marwan H, Alsaedi, Basim S. O

“…Background: Type 2 diabetes (T2D) is a metabolic condition induced by insulin resistance and pancreatic beta cell dysfunction. MicroRNAs (miRNAs) have…”
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Whole-Exome Sequencing Detecting a Recurrent Pathogenic Mutation, HFE p.His63Asp (H63D) in COVID-19 Patients and Its Effect on Mortality by Mir, Rashid, Elfaki, Imadeldin, Alanazi, Mohammad A, Algehainy, Naseh A, Altemani, Faisal H, Alsayed, Badr A, Mohamed, Elsiddig Idriss, Mustafa, Syed Khalid, Moawadh, Mamdoh S, Tayeb, Faris J, Alfaifi, Jaber, Alatawi, Sael M, Mir, Mohammad Muzaffar, Ullah, Mohammad Fahad

“…In recent years, various coronaviruses have caused severe respiratory illnesses worldwide. For example the severe acute respiratory syndrome coronavirus-2…”
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Investigation of the Protective Effects of IUrtica dioica/I, ICapsella bursa-pastoris/I and IInula racemosa/I on Acetaminophen-Induced Nephrotoxicity in Swiss Albino Male Mice by Yousuf, Sumaira, Shabir, Shabnam, Mehdi, Mohammad Murtaza, Srivastav, Shailesh, Mohammedsaleh, Zuhair M, Bassfar, Zaid, Jalal, Mohammed M, Moawadh, Mamdoh S, Jamous, Yahya F, Singh, Sandeep Kumar, Vamanu, Emanuel, Singh, Mahendra P

“…Acetaminophen (APAP) is the most commonly used nonprescription antipyretic-analgesic drug. This medication is thought to be safe at the suggested dosage (4…”
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