Search Results - "Moatasim, Yassmin"
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Scrutinizing the Feasibility of Nonionic Surfactants to Form Isotropic Bicelles of Curcumin: a Potential Antiviral Candidate Against COVID-19
Published in AAPS PharmSciTech (29-12-2021)“…Investigating bicelles as an oral drug delivery system and exploiting their structural benefits can pave the way to formulate hydrophobic drugs and potentiate…”
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Robust antiviral activity of commonly prescribed antidepressants against emerging coronaviruses: in vitro and in silico drug repurposing studies
Published in Scientific reports (28-07-2022)“…During the current coronavirus disease 2019 (COVID-19) pandemic, symptoms of depression are commonly documented among both symptomatic and asymptomatic…”
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EGYVIR: An immunomodulatory herbal extract with potent antiviral activity against SARS-CoV-2
Published in PloS one (18-11-2020)“…Due to the challenges for developing vaccines in devastating pandemic situations of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), developing…”
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FDA-Approved Drugs with Potent In Vitro Antiviral Activity against Severe Acute Respiratory Syndrome Coronavirus 2
Published in Pharmaceuticals (Basel, Switzerland) (04-12-2020)“…(1) Background: Drug repositioning is an unconventional drug discovery approach to explore new therapeutic benefits of existing drugs. Currently, it emerges as…”
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Genetic characterization of highly pathogenic avian influenza A H5N8 viruses isolated from wild birds in Egypt
Published in Journal of general virology (01-07-2017)“…A newly emerged H5N8 influenza virus was isolated from green-winged teal in Egypt during December 2016. In this study, we provide a detailed characterization…”
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Bioactive Polyphenolic Compounds Showing Strong Antiviral Activities against Severe Acute Respiratory Syndrome Coronavirus 2
Published in Pathogens (Basel) (15-06-2021)“…Until now, there has been no direct evidence of the effectiveness of repurposed FDA-approved drugs against Severe Acute Respiratory Syndrome Coronavirus 2…”
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Design, Synthesis and In Vitro Evaluation of Spirooxindole-Based Phenylsulfonyl Moiety as a Candidate Anti-SAR-CoV-2 and MERS-CoV-2 with the Implementation of Combination Studies
Published in International journal of molecular sciences (01-10-2022)“…The search for an effective anti-viral to inhibit COVID-19 is a challenge for the specialized scientific research community. This work investigated the…”
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Assessment of toxicity and antimicrobial performance of polymeric inorganic coagulant and evaluation for eutrophication reduction
Published in Scientific reports (09-02-2024)“…In this study, the efficacy of the promising iron—based polymeric inorganic coagulant (POFC) was assessed for the reduction of eutrophication effect…”
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Genetic and antigenic evolution of H9N2 avian influenza viruses circulating in Egypt between 2011 and 2013
Published in Archives of virology (01-11-2014)“…Avian influenza virus subtype H9N2 has been circulating in the Middle East since the 1990s. For uncertain reasons, H9N2 was not detected in Egyptian farms…”
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Development of spiro-3-indolin-2-one containing compounds of antiproliferative and anti-SARS-CoV-2 properties
Published in Scientific reports (16-08-2022)“…A series of 1″-(alkylsulfonyl)-dispiro[indoline-3,2′-pyrrolidine-3′,3″-piperidine]-2,4″-diones 6a‒o has been synthesized through regioselective multi-component…”
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Active surveillance for avian influenza virus, Egypt, 2010-2012
Published in Emerging infectious diseases (01-04-2014)“…Continuous circulation of influenza A(H5N1) virus among poultry in Egypt has created an epicenter in which the viruses evolve into newer subclades and continue…”
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Incidence, household transmission, and neutralizing antibody seroprevalence of Coronavirus Disease 2019 in Egypt: Results of a community-based cohort
Published in PLoS pathogens (01-03-2021)“…SARS-CoV-2 virus is transmitted in closed settings to people in contact with COVID-19 patients such as healthcare workers and household contacts. However,…”
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Molecular characterization of avian influenza H5N1 virus in Egypt and the emergence of a novel endemic subclade
Published in Journal of general virology (01-07-2014)“…Clade 2.2 highly pathogenic H5N1 viruses have been in continuous circulation in Egyptian poultry since 2006. Their persistence caused significant genetic drift…”
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Design and statistical optimisation of emulsomal nanoparticles for improved anti-SARS-CoV-2 activity of N-(5-nitrothiazol-2-yl)-carboxamido candidates: in vitro and in silico studies
Published in Journal of enzyme inhibition and medicinal chemistry (01-12-2023)“…In this article, emulsomes (EMLs) were fabricated to encapsulate the N-(5-nitrothiazol-2-yl)-carboxamido derivatives (3a-3g) in an attempt to improve their…”
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Common childhood vaccines do not elicit a cross-reactive antibody response against SARS-CoV-2
Published in PloS one (28-10-2020)“…Anecdotal evidence showed a negative correlation between Bacille Calmette-Guérin (BCG) vaccination and incidence of COVID-19. Incidence of the disease in…”
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Antiviral activity of Humulus lupulus (HOP) aqueous extract against MERS-CoV and SARS-CoV-2: in-vitro and in-silico study
Published in Biotechnology, biotechnological equipment (31-12-2023)“…Coronaviruses emerged three times in the last two decades and became a source of concern globally. Humulus lupulus plant has been used widely in medical…”
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Comparison of SARS-Cov-2 omicron variant with the previously identified SARS-Cov-2 variants in Egypt, 2020–2022: insight into SARS-Cov-2 genome evolution and its impact on epidemiology, clinical picture, disease severity, and mortality
Published in BMC infectious diseases (18-08-2023)“…Abstract Background The o severe acute respiratory coronavirus 2 (SARS-CoV-2) pandemic has killed millions of people and caused widespread concern around the…”
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Insights into Genetic Characteristics and Virological Features of Endemic Avian Influenza A (H9N2) Viruses in Egypt from 2017-2021
Published in Viruses (06-07-2022)“…From 2010 to 2013, genotype I avian influenza A(H9N2) viruses of the G1-lineage were isolated from several poultry species in Egypt. In 2014, novel reassortant…”
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Highly pathogenic avian influenza virus H5N1 clade 2.3.4.4b in wild rats in Egypt during 2023
Published in Emerging microbes & infections (01-12-2024)“…We detected highly pathogenic avian influenza A(H5N1) virus in wild rats collected from a rural area in Giza, Egypt, near poultry farms, markets, and backyard…”
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Structure- and Ligand-Based in silico Studies towards the Repurposing of Marine Bioactive Compounds to Target SARS-CoV-2
Published in Arabian journal of chemistry (01-04-2021)“…[Display omitted] This work was a structured virtual screening for marine bioactive compounds with reported antiviral activities which were subjected to…”
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