Search Results - "Mörike, Klaus"
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1
Mechanisms and assessment of statin‐related muscular adverse effects
Published in British journal of clinical pharmacology (01-09-2014)“…Statin‐associated muscular adverse effects cover a wide range of symptoms, including asymptomatic increase of creatine kinase serum activity and…”
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2
Pharmacogenetics of antimalarial drugs: effect on metabolism and transport
Published in The Lancet infectious diseases (01-12-2009)“…Summary The prevention and management of malaria is primarily based on the use of drugs. Clinical trials have however revealed that between individuals there…”
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3
Dose-Proportional Intraindividual Single- and Repeated-Dose Pharmacokinetics of Roflumilast, an Oral, Once-Daily Phosphodiesterase 4 Inhibitor
Published in Journal of clinical pharmacology (01-01-2007)“…The dose‐proportional, intraindividual, single‐ and repeated‐dose pharmacokinetics of roflumilast, an oral, once‐daily phosphodiesterase 4 inhibitor under…”
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4
No Dose Adjustment on Coadministration of the PDE4 Inhibitor Roflumilast With a Weak CYP3A, CYP1A2, and CYP2C19 Inhibitor: An Investigation Using Cimetidine
Published in Journal of clinical pharmacology (01-04-2011)“…This nonrandomized, fixed‐sequence, 2‐period crossover study investigated potential pharmacokinetic interactions between the phosphodiesterase 4 inhibitor…”
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5
Clinical pharmacokinetics of candesartan
Published in Clinical pharmacokinetics (2002)“…Candesartan cilexetil is the prodrug of candesartan, an angiotensin II type 1 (AT1) receptor antagonist. Absorbed candesartan cilexetil is completely…”
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6
Off label prescribing to children in primary care in Germany: retrospective cohort study
Published in BMJ (01-06-2002)“…Contributors: MS, KM, and CG designed the study. PS provided access to Allgemeine Ortskrankenkasse, BadenWurttemberg, and gave information concerning drug…”
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7
Ginger-Associated Overanticoagulation by Phenprocoumon
Published in The Annals of pharmacotherapy (01-02-2004)“…OBJECTIVE To report a case of ginger–phenprocoumon interaction resulting in an elevated international normalized ratio (INR) and epistaxis. CASE SUMMARY A…”
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8
Effect of High-Dose Metronidazole on Pharmacokinetics of Oral Budesonide and Vice Versa: A Double Drug Interaction Study
Published in Journal of clinical pharmacology (01-12-2007)“…Recent case reports suggest that addition of high‐dose metronidazole might be associated with elevated plasma concentrations of substrates of cytochrome P450…”
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9
Salbutamol-Infusion erhöht Mortalität bei der Schocklunge
Published in MMW Fortschritte der Medizin (01-06-2012)“…Beim akuten Lungen-Schädigungssyndrom scheint eine frühe intravenöse Salbutamol-Infusion die Sterblichkeit zu erhöhen. Zudem wird sie schlecht vertragen…”
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10
Polypharmacy-an Upward Trend with Unpredictable Effects
Published in Deutsches Ärzteblatt international (23-09-2016)“…Guideline-oriented treatments can lead to polypharmacy, i.e., the simultaneous long-term use of multiple drugs. Polypharmacy mainly affects elderly patients…”
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11
The clinical implications of ageing for rational drug therapy
Published in European journal of clinical pharmacology (01-02-2008)“…Introduction The proportion of the elderly is constantly increasing and by the year 2025 20% of the population will be above 65 years of age. With advanced…”
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12
Chronic Heart Failure
Published in Deutsches Ärzteblatt international (23-02-2018)“…Chronic heart failure (CHF) is the most common reason for hospital admissions in Germany. For the National Disease Management Guideline (NDMG) on CHF, a…”
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13
Dietary salt increases first-pass elimination of oral quinidine
Published in Clinical pharmacology and therapeutics (01-03-1997)“…Background Some cytochrome P450 (CYP) enzymes, including CYP3A, are expressed not only in the liver but also in the intestine; the latter may therefore be an…”
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14
Gleichgewichtsstörungen: Ist die Gentamicin-Therapie schuld?
Published in Hno-Nachrichten (01-04-2018)Get full text
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15
Problems in anticoagulation of a patient with antibiotic treatment for endocarditis: interaction of rifampicin and vitamin K antagonists
Published in BMJ case reports (12-02-2018)“…The cytochrome P450 is a superfamily of isoenzymes that are responsible for the metabolism of many drugs. Significant changes in pharmacokinetics and drug…”
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16
Herausforderungen der Tuberkulosetherapie
Published in Pneumo news (01-12-2015)Get full text
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17
Proximal femur fracture in older patients – rehabilitation and clinical outcome
Published in Age and ageing (01-01-2003)“…Background: hip fracture is a major cause of morbidity and mortality in older people; optimal post‐surgical treatment is a matter of controversy. Objective: to…”
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18
P2X3-Rezeptor-Antagonisten — eine Renaissance für wirksame Antitussiva?
Published in Pneumo news (01-10-2015)Get full text
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19
Vitamin-D-Gabe beschleunigt die Sputumkonversion bei Tbc nicht
Published in Pneumo news (01-09-2015)Get full text
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20
Severe gastrointestinal haemorrhage after methimazole intake
Published in Clinical endocrinology (Oxford) (01-05-2011)Get full text
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