Search Results - "Moïse, Nadia Pellegrini"
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1
PET/Fluorescence Imaging: An Overview of the Chemical Strategies to Build Dual Imaging Tools
Published in Bioconjugate chemistry (19-01-2022)“…Molecular imaging is a biomedical research discipline that has quickly emerged to afford the observation, characterization, monitoring, and quantification of…”
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2
Synthesis of anti-proliferative [3.3.0]furofuranone derivatives by lactonization and functionalization of C-glycosyl compounds
Published in Bioorganic & medicinal chemistry (01-09-2021)“…[Display omitted] The [3.3.0]furofuranone structure is found in numerous families of biologically active natural products. We took advantage of the…”
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3
NRP1 inhibition modulates radiosensitivity of medulloblastoma by targeting cancer stem cells
Published in Cancer cell international (01-12-2022)“…Medulloblastoma (MB) is the most common pediatric malignant brain tumor. Despite current therapies, the morbidity and recurrent risk remains significant…”
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4
Base- and Radical-Mediated Regio- and Stereoselective Additions of Thiols, Thio-Sugars, and Thiol-Containing Peptides to Trisubstituted Activated exo-Glycals
Published in European journal of organic chemistry (01-04-2015)“…A study was performed for the coupling of thiols, thio‐sugars, and thiol‐containing amino acids and peptides with trisubstituted activated anomeric sugar…”
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5
Toward Bis C,C-Glycosyl Compounds and Anomeric γ-Glycoamino Acids through Michael Addition Reaction of Nitromethane on Z/E Push-Pull Sugar Olefins
Published in European journal of organic chemistry (01-11-2014)“…The nucleophilic addition of a nitronate anion on push‐pull anomeric sugar olefins has been studied and the results reveal that this reaction opens a new and…”
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6
Synthesis and Copper(II)-Complexation Properties of an Unusual Macrocyclic Structure Containing α/β-Amino Acids and Anomeric Sugar β-Amino Acid
Published in European journal of organic chemistry (01-09-2013)“…A 16‐membered macrocycle containing histidine, β‐alanine, and an anomeric sugar β‐amino acid was synthesised using a stepwise procedure starting from an…”
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7
Sugar γ‐Amino Acids as Building Blocks for the Synthesis of Cyclic Neoglycopeptides
Published in ChemistrySelect (Weinheim) (23-08-2018)“…Anomeric sugar γ‐amino acids efficiently obtained by nucleophilic addition of nitronate anion on sugar olefins are useful building blocks for the preparation…”
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8
Tetrasubstituted C-Glycosylidenes and C-Glycosyl Compounds from Di- and Monobromo-Substituted exo-Glycals
Published in European Journal of Organic Chemistry (01-12-2011)“…Efficient methods for functionalization of readily available exo‐glycals have been developed. Sequential palladium‐catalysed cross‐coupling of…”
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Multimodal PET/PAI/FLI imaging probe based on meso-O-alkyl heptamethine cyanine: Synthesis, [18F]F-radiolabelling and photophysical characterizations
Published in Dyes and pigments (01-04-2024)“…The combination of positron emission tomography (PET)/photoacoustic imaging (PAI)/fluorescence imaging (FLI) for diagnosis allows to exploit the strengths and…”
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10
Value-added carbohydrate building blocks by regioselective O-alkylation of C-glucosyl compounds
Published in Carbohydrate research (15-05-2019)“…Functionalized carbohydrates and especially functionalized C-glycosides are useful intermediates for the synthesis of complex carbohydrates of interest. In…”
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11
Stimulation of medulloblastoma stem cells differentiation by a peptidomimetic targeting neuropilin-1
Published in Oncotarget (16-03-2018)“…Medulloblastoma (MB) is the most common malignant pediatric brain tumor. Despite the progress of new treatments, the risk of recurrence, morbidity, and death…”
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12
Synthesis of a DOTA- C -glyco bifunctional chelating agent and preliminary in vitro and in vivo study of [ 68 Ga]Ga-DOTA- C -glyco-RGD
Published in RSC advances (17-02-2021)“…The design of bifunctional chelating agents (BFCA) allowing straightforward radiometal labelling of biomolecules is a current challenge. We report herein the…”
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13
Synthesis and conformational studies of short mixed γ/α-glycopeptides based on sugar γ 3,3 -amino acids
Published in Tetrahedron (01-11-2017)“…Carbohydrates bearing both amino and carboxylate groups could be useful for expanding the repertoire of monomers used for building foldamers. In this paper, we…”
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14
Carbohydrate-based peptidomimetics targeting neuropilin-1: Synthesis, molecular docking study and in vitro biological activities
Published in Bioorganic & medicinal chemistry (01-11-2016)“…[Display omitted] Neuropilin-1 (NRP-1), a transmembrane glycoprotein acting as a co-receptor of VEGF-A, is expressed by cancer and angiogenic endothelial cells…”
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15
Spiro sugar-isoxazolidine scaffold as useful polyfunctional building block for peptidomimetics design
Published in Carbohydrate research (03-03-2016)“…•The development and functionalization of a bicyclic carbohydrate-based scaffold are proposed.•Spiro sugar-isoxazolidines efficiently functionalized at two…”
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16
Synthesis and revised stereochemical assignment of C-allyl glucopyranosides and derivatives
Published in Carbohydrate research (05-06-2017)“…α- and β-C-allylglucopyranosides and hydroxy-, bromo- and azido-derivatives were prepared through allylation at C-1 of methyl…”
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17
Sugar-based peptidomimetics as potential inhibitors of the vascular endothelium growth factor binding to neuropilin-1
Published in Bioorganic & medicinal chemistry (01-05-2010)“…Neuropilin-1 (NRP-1) is a co-receptor of VEGFR165 and molecules interfering with VEGF165 binding to NRP-1 seem to be promising candidates as new angiogenesis…”
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18
The 1,3-dipolar cycloaddition reaction of chiral carbohydrate-derived nitrone and olefin: towards long-chain sugars
Published in Carbohydrate research (15-11-2013)“…•Long-chain carbohydrates are obtained by nitrone–olefin cycloadditions.•d-Mannose-derived octulonic ester and l-threitol-derived nitrone correspond to a…”
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19
Clickable C -Glycosyl Scaffold for the Development of a Dual Fluorescent and [ 18 F]fluorinated Cyanine-Containing Probe and Preliminary In Vitro/Vivo Evaluation by Fluorescence Imaging
Published in Pharmaceuticals (Basel, Switzerland) (29-11-2022)“…Considering the individual characteristics of positron emission tomography (PET) and optical imaging (OI) in terms of sensitivity, spatial resolution, and…”
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20
Efficient access to disubstituted exo-glycals. Application to the preparation of C-glycosyl compounds
Published in Tetrahedron letters (25-11-2009)“…Efficient methods of preparation of disubstituted exo-glycals by palladium cross-coupling reaction on the readily available dibromo exo-glycal and…”
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