Search Results - "Mo, Xiaobing"
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Insights into the inhibition of protospacer integration via direct interaction between Cas2 and AcrVA5
Published in Nature communications (16-04-2024)“…Spacer acquisition step in CRISPR-Cas system involves the recognition and subsequent integration of protospacer by the Cas1-Cas2 complex in CRISPR-Cas systems…”
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Structural roles of PCV2 capsid protein N-terminus in PCV2 particle assembly and identification of PCV2 type-specific neutralizing epitope
Published in PLoS pathogens (01-03-2019)“…Postweaning multisystemic wasting disease (PMWS) in piglets caused by porcine circovirus type 2 (PCV2) is one of the major threats to most pig farms worldwide…”
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Epidemiological investigation and analysis of the infection of porcine circovirus in Xinjiang
Published in Virology journal (27-09-2024)“…Porcine circoviruses, particularly porcine circovirus type 2 (PCV2) and porcine circovirus type 3 (PCV3), significantly impact the global pig industry due to…”
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N-terminal truncations on L1 proteins of human papillomaviruses promote their soluble expression in Escherichia coli and self-assembly in vitro
Published in Emerging microbes & infections (26-09-2018)“…Human papillomavirus (HPV) is the causative agent in genital warts and nearly all cervical, anogenital, and oropharyngeal cancers. Nine HPV types (6, 11, 16,…”
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The Vestigial Esterase Domain of Haemagglutinin of H5N1 Avian Influenza A Virus: Antigenicity and Contribution to Viral Pathogenesis
Published in Vaccines (Basel) (10-08-2018)“…Initial attempts to develop monoclonal antibodies as therapeutics to resolve influenza infections focused mainly on searching for antibodies with the potential…”
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Structural insights into Drosophila-C3PO complex assembly and 'Dynamic Side Port' model in substrate entry and release
Published in Nucleic acids research (19-09-2018)“…Abstract In Drosophila and human, component 3 promoter of RISC (C3PO), a heteromeric complex, enhances RISC assembly and promotes RISC activity. Here, we…”
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Biochemical and structural insights into an Ochrobactrum sp. CSL1 ribose-5-phosphate isomerase A and its roles in isomerization of rare sugars
Published in Enzyme and microbial technology (01-10-2020)“…[Display omitted] •1 Evaluated biochemical properties of Rpi A & B from a newly screened Ochrobactrum sp.•2 Unveiled the unique substrate scope of RpiA for…”
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Structural insight into the type-specific epitope of porcine circovirus type 3
Published in Bioscience reports (26-06-2020)“…The recently identified pathogenic Porcine circovirus type 3 (PCV3) may threaten to reduce the pig population dramatically worldwide. In our previous study, a…”
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Large-scale production of foot-and-mouth disease virus (serotype Asia1) VLP vaccine in Escherichia coli and protection potency evaluation in cattle
Published in BMC biotechnology (02-07-2016)“…Foot-and-mouth disease (FMD) is an acute, highly contagious disease that infects cloven-hoofed animals. Vaccination is an effective means of preventing and…”
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Effects of Boron on the Microstructure,Ductility-dip-cracking,and Tensile Properties for NiCrFe-7 Weld Metal
Published in Journal of materials science & technology (01-12-2015)“…The distribution of boron and the microstructure of grain boundary(GB) precipitates(M23(C,B) 6 and M 2B)have been analyzed with their effects on the…”
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Production of Escherichia coli-based virus-like particle vaccine against porcine circovirus type 2 challenge in piglets: Structure characterization and protective efficacy validation
Published in Journal of biotechnology (10-04-2016)“…•Soluble non-tag full-length PCV2 capsid protein (rCap) was produced in Escherichia coli and self-assembled into VLP in vitro.•The Cryo-EM structure of PCV2…”
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Expression, purification and immunogenicity analysis of HPV type 18 virus-like particles from Escherichia coli
Published in Shengwu gongcheng xuebao (01-07-2009)“…Here, we presented a method to bacterially express the major structural protein L1 of Human Papillomavirus type 18 (HPV18) as soluble form. We found that the…”
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