Search Results - "Mo, Jiezhen"

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  1. 1

    Detection of Human Urinary 5‑Hydroxymethylcytosine by Stable Isotope Dilution HPLC-MS/MS Analysis by Yin, Ruichuan, Mo, Jiezhen, Lu, Meiling, Wang, Hailin

    Published in Analytical chemistry (Washington) (03-02-2015)
    “…The sixth DNA base 5-hydroxymethylcytosine (5hmC) is the major oxidation product of the epigenetic modification 5-methylcytosine (5mC), mediating DNA…”
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    Journal Article
  2. 2

    Global DNA 5‐Hydroxymethylcytosine and 5‐Formylcytosine Contents Are Decreased in the Early Stage of Hepatocellular Carcinoma by Liu, Jiao, Jiang, Jinhua, Mo, Jiezhen, Liu, Dan, Cao, Dan, Wang, Hailin, He, Yufei, Wang, Hongyang

    Published in Hepatology (Baltimore, Md.) (01-01-2019)
    “…Methylation of the fifth position of cytosine (5mC) is an important epigenetic modification of DNA. It has been shown that the oxidized derivatives of 5mC,…”
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    Journal Article
  3. 3

    Profiling of epigenetic DNA modifications by advanced liquid chromatography-mass spectrometry technologies by Lai, Weiyi, Mo, Jiezhen, Yin, Junfa, Lyu, Cong, Wang, Hailin

    “…Four DNA bases are essential biochemical elements for coding heritable life blueprint. Meanwhile, organisms utilize modifying enzymes to post chemical groups…”
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  4. 4

    Nickel(II) Inhibits Tet-Mediated 5‑Methylcytosine Oxidation by High Affinity Displacement of the Cofactor Iron(II) by Yin, Ruichuan, Mo, Jiezhen, Dai, Jiayin, Wang, Hailin

    Published in ACS chemical biology (16-06-2017)
    “…Ten-eleven translocation (Tet) family proteins are Fe­(II)- and 2-oxoglutarate-dependent dioxygenases that regulate the dynamics of DNA methylation by…”
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  5. 5

    Nickel(ii) inhibits the oxidation of DNA 5-methylcytosine in mammalian somatic cells and embryonic stem cells by Yin, Ruichuan, Mo, Jiezhen, Dai, Jiayin, Wang, Hailin

    Published in Metallomics (01-03-2018)
    “…Nickel is found widely in the environment. It is an essential microelement but also toxic. However, nickel displays only weak genotoxicity and mutagenicity…”
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  6. 6

    Author Correction: N6-methyladenine is incorporated into mammalian genome by DNA polymerase by Liu, Xiaoling, Lai, Weiyi, Li, Yao, Chen, Shaokun, Liu, Baodong, Zhang, Ning, Mo, Jiezhen, Lyu, Cong, Zheng, Jing, Du, Ya-Rui, Jiang, Guibin, Xu, Guo-Liang, Wang, Hailin

    Published in Cell research (01-02-2021)
    “…An amendment to this paper has been published and can be accessed via a link at the top of the paper…”
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    Journal Article
  7. 7
  8. 8

    Protonation-Suppression-Free LC-MS/MS Analysis for Profiling of DNA Cytosine Modifications in Adult Mice by Mo, Jiezhen, Liang, Ziyu, Lu, Meiling, Wang, Hailin

    Published in Analytical chemistry (Washington) (02-06-2020)
    “…DNA cytosine modifications are important epigenetic marks. To elucidate their roles by a large scale of comparative studies, it is important to quantify the…”
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  9. 9
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    Structural insights into molecular mechanism for N6-adenosine methylation by MT-A70 family methyltransferase METTL4 by Luo, Qiang, Mo, Jiezhen, Chen, Hao, Hu, Zetao, Wang, Baihui, Wu, Jiabing, Liang, Ziyu, Xie, Wenhao, Du, Kangxi, Peng, Maolin, Li, Yingping, Li, Tianyang, Zhang, Yangyi, Shi, Xiaoyan, Shen, Wen-Hui, Shi, Yang, Dong, Aiwu, Wang, Hailin, Ma, Jinbiao

    Published in Nature communications (26-09-2022)
    “…METTL4 belongs to a subclade of MT-A70 family members of methyltransferase (MTase) proteins shown to mediate N 6 -adenosine methylation for both RNA and DNA in…”
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    Journal Article
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  13. 13

    Structural insights into molecular mechanism for N 6 -adenosine methylation by MT-A70 family methyltransferase METTL4 by Luo, Qiang, Mo, Jiezhen, Chen, Hao, Hu, Zetao, Wang, Baihui, Wu, Jiabing, Liang, Ziyu, Xie, Wenhao, Du, Kangxi, Peng, Maolin, Li, Yingping, Li, Tianyang, Zhang, Yangyi, Shi, Xiaoyan, Shen, Wen-Hui, Shi, Yang, Dong, Aiwu, Wang, Hailin, Ma, Jinbiao

    Published in Nature communications (26-09-2022)
    “…METTL4 belongs to a subclade of MT-A70 family members of methyltransferase (MTase) proteins shown to mediate N -adenosine methylation for both RNA and DNA in…”
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    Journal Article
  14. 14

    Structural insights into molecular mechanism for N 6-adenosine methylation by MT-A70 family methyltransferase METTL4 by Qiang Luo, Jiezhen Mo, Hao Chen, Zetao Hu, Baihui Wang, Jiabing Wu, Ziyu Liang, Wenhao Xie, Kangxi Du, Maolin Peng, Yingping Li, Tianyang Li, Yangyi Zhang, Xiaoyan Shi, Wen-Hui Shen, Yang Shi, Aiwu Dong, Hailin Wang, Jinbiao Ma

    Published in Nature communications (01-09-2022)
    “…Here the authors combine functional and structural work to show that METTL4 functions as U2 snRNA m6Am RNA methyltransferase supporting N6-methylation of…”
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