Search Results - "Mizuochi, Toshiaki"

Autophagic Compartments Gain Access to the MHC Class II Compartments in Thymic Epithelium by Kasai, Michiyuki, Tanida, Isei, Ueno, Takashi, Kominami, Eiki, Seki, Sachiko, Ikeda, Tohru, Mizuochi, Toshiaki

“…The presentation of self-peptides in the context of MHC molecules by thymic epithelial cells (TECs) is essential for T cell repertoire selection in the thymus…”
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Japanese Reference Panel of Blood Specimens for Evaluation of Hepatitis C Virus RNA and Core Antigen Quantitative Assays by MURAYAMA, Asako, SUGIYAMA, Nao, WATASHI, Koichi, MASAKI, Takahiro, SUZUKI, Ryosuke, AIZAKI, Hideki, MIZUOCHI, Toshiaki, WAKITA, Takaji, KATO, Takanobu

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B-cell-intrinsic hepatitis C virus expression leads to B-cell-lymphomagenesis and induction of NF-κB signalling by Kasama, Yuri, Mizukami, Takuo, Kusunoki, Hideki, Peveling-Oberhag, Jan, Nishito, Yasumasa, Ozawa, Makoto, Kohara, Michinori, Mizuochi, Toshiaki, Tsukiyama-Kohara, Kyoko

“…Hepatitis C virus (HCV) infection leads to the development of hepatic diseases, as well as extrahepatic disorders such as B-cell non-Hodgkin's lymphoma…”
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Peripheral blood memory B cells are resistant to apoptosis in chronic hepatitis C patients by Mizuochi, Toshiaki, Ito, Masahiko, Takai, Kenji, Yamaguchi, Kazunari

“…Our recent study indicated that peripheral B cells in chronic hepatitis C (CHC) patients were infected with hepatitis C virus (HCV). It was also demonstrated…”
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Enhanced expression of lymphomagenesis-related genes in peripheral blood B cells of chronic hepatitis C patients by Ito, Masahiko, Murakami, Kyoko, Suzuki, Tetsuro, Mochida, Keiko, Suzuki, Miho, Ikebuchi, Kenji, Yamaguchi, Kazunari, Mizuochi, Toshiaki

“…Abstract Epidemiological data indicate a close relationship between chronic hepatitis C virus (HCV) infection and B-cell non-Hodgkin's lymphoma (B-NHL),…”
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Murine Macrophages Produce Secretory Leukocyte Protease Inhibitor During Clearance of Apoptotic Cells: Implications for Resolution of the Inflammatory Response by Odaka, Chikako, Mizuochi, Toshiaki, Yang, Jingxuan, Ding, Aihao

“…Macrophage-derived secretory leukocyte protease inhibitor (SLPI) can be induced locally as well as systemically in response to microbial products such as LPS…”
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Differential susceptibility of peripheral blood CD5 + and CD5 − B cells to apoptosis in chronic hepatitis C patients by Mizuochi, Toshiaki, Ito, Masahiko, Takai, Kenji, Yamaguchi, Kazunari

“…A body of evidence has suggested a close link between chronic hepatitis C virus (HCV) infection and B cell abnormalities, including mixed cryoglobulinemia,…”
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Development of an Infectious Surrogate Hepatitis C Virus Based on a Recombinant Vesicular Stomatitis Virus Expressing Hepatitis C Virus Envelope Glycoproteins and Green Fluorescent Protein by Okuma, Kazu, Fukagawa, Koji, Tateyama, Seiji, Kohma, Takuya, Mochida, Keiko, Hiyoshi, Masateru, Takahama, Youichi, Hamaguchi, Yukio, Hirose, Kunitaka, Buonocore, Linda, Rose, John K., Mizuochi, Toshiaki, Hamaguchi, Isao

“…To develop surrogate viruses for hepatitis C virus (HCV), we previously produced recombinant vesicular stomatitis viruses (rVSVs) lacking glycoprotein G but…”
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Evaluation of Hepatitis C Virus Core Antigen Assays in Detecting Recombinant Viral Antigens of Various Genotypes by Saeed, Mohsan, Suzuki, Ryosuke, Kondo, Madoka, Aizaki, Hideki, Kato, Takanobu, Mizuochi, Toshiaki, Wakita, Takaji, Watanabe, Haruo, Suzuki, Tetsuro

“…A single substitution within the hepatitis C virus core antigen sequence, A48T, which is observed in ~30% of individuals infected with genotype 2a virus,…”
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HCV Infection and B-Cell Lymphomagenesis by Ito, Masahiko, Kusunoki, Hideki, Mochida, Keiko, Yamaguchi, Kazunari, Mizuochi, Toshiaki

“…Hepatitis C virus (HCV) has been recognized as a major cause of chronic liver diseases worldwide. It has been suggested that HCV infects not only hepatocytes…”
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Peripheral B Cells May Serve as a Reservoir for Persistent Hepatitis C Virus Infection by Ito, Masahiko, Masumi, Atsuko, Mochida, Keiko, Kukihara, Hiroshi, Moriishi, Kohji, Matsuura, Yoshiharu, Yamaguchi, Kazunari, Mizuochi, Toshiaki

“…A recent study by our group indicated that peripheral B cells in chronic hepatitis C (CHC) patients are infected with hepatitis C virus (HCV). This raised the…”
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Possible recruitment of peripheral blood CXCR3+ CD27+ CD19+ B cells to the liver of chronic hepatitis C patients by Mizuochi, Toshiaki, Ito, Masahiko, Saito, Koji, Kasai, Michiyuki, Kunimura, Toshiaki, Morohoshi, Toshio, Momose, Haruka, Hamaguchi, Isao, Takai, Kenji, Iino, Shiro, Suzuki, Miho, Mochida, Satoshi, Ikebuchi, Kenji, Yamaguchi, Kazunari

“…It has been suggested that hepatitis C virus (HCV) infects not only hepatocytes but also immune cells, including B cells. HCV infection of B cells is the…”
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Role of Macrophage Lysosomal Enzymes in the Degradation of Nucleosomes of Apoptotic Cells by Odaka, Chikako, Mizuochi, Toshiaki

“…Although apoptotic cells are recognized and engulfed by macrophages via a number of membrane receptors, little is known about the fate of apoptotic cells after…”
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Evaluation of 10 commercial diagnostic kits for in vitro expressed hepatitis B virus (HBV) surface antigens encoded by HBV of genotypes A to H by Mizuochi, Toshiaki, Okada, Yoshiaki, Umemori, Kiyoko, Mizusawa, Saeko, Yamaguchi, Kazunari

“…Genetic variability of the hepatitis B virus (HBV) constitutes one of the major challenges for diagnosis of HBV infection. It is plausible that amino acid…”
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Peripheral B cells as reservoirs for persistent HCV infection by Ito, Masahiko, Kusunoki, Hideki, Mizuochi, Toshiaki

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Reactivity of Genotypically Distinct Hepatitis B Virus Surface Antigens in 10 Commercial Diagnostic Kits Available in Japan by Mizuochi, Toshiaki, Okada, Yoshiaki, Umemori, Kiyoko, Mizusawa, Saeko, Sato, Shinichiro, Yamaguchi, Kazunari

“…Hepatitis B virus (HBV) surface antigen (HBsAg) is one of the most important serological markers of current HBV infection. However, there are significant…”
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Difference in antigen presentation pathways between cortical and medullary thymic epithelial cells by Kasai, M, Hirokawa, K, Kajino, K, Ogasawara, K, Tatsumi, M, Hermel, E, Monaco, J J, Mizuochi, T

“…Antigen presentation by thymic epithelial cells (TEC) to T cells that undergo maturation is one of the major events in the selection of the T cell repertoire…”
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Both cathepsin B and cathepsin D are necessary for processing of ovalbumin as well as for degradation of class II MHC invariant chain by Mizuochi, T, Yee, S T, Kasai, M, Kakiuchi, T, Muno, D, Kominami, E

“…The effect of highly selective inhibitors of cathepsins on the processing of ovalbumin (OVA) and the presentation of an OVA-derived antigenic peptide…”
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Heterosexual Transmission of a Murine AIDS Virus by Okada, Y, Abe, E, Komuro, K, Mizuochi, T

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Geographic distribution and characteristics of genotype A hepatitis B virus infection in acute and chronic hepatitis B patients in Japan by Ito, Kiyoaki, Yotsuyanagi, Hiroshi, Sugiyama, Masaya, Yatsuhashi, Hiroshi, Karino, Yoshiyasu, Takikawa, Yasuhiro, Saito, Takafumi, Arase, Yasuji, Imazeki, Fumio, Kurosaki, Masayuki, Umemura, Takeji, Ichida, Takafumi, Toyoda, Hidenori, Yoneda, Masashi, Tanaka, Yasuhito, Mita, Eiji, Yamamoto, Kazuhide, Michitaka, Kojiro, Maeshiro, Tatsuji, Tanuma, Junko, Korenaga, Masaaki, Murata, Kazumoto, Masaki, Naohiko, Koike, Kazuhiko, Mizokami, Masashi

“…Background and Aims The prevalence of sexually transmitted acute infections of the genotype A hepatitis B virus (HBV) has been increasing in Japan. Genotype A…”
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