Search Results - "Mizuno, Narumi"
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Optimization of Albumin Secretion and Metabolic Activity of Cytochrome P450 1A1 of Human Hepatoblastoma HepG2 Cells in Multicellular Spheroids by Controlling Spheroid Size
Published in Biological & pharmaceutical bulletin (2017)“…Multicellular spheroids are useful as three-dimensional cell culture systems and for cell-based therapies. Their successful application requires an…”
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Transplantation of insulin-secreting multicellular spheroids for the treatment of type 1 diabetes in mice
Published in Journal of controlled release (10-01-2014)“…The efficacy of cell-based therapy depends on the function and survival of transplanted cells, which have been suggested to be enhanced by spheroid formation…”
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Increased Insulin Secretion from Insulin-Secreting Cells by Construction of Mixed Multicellular Spheroids
Published in Pharmaceutical research (01-01-2016)“…Purpose We previously have shown that multicellular spheroids containing insulin-secreting cells are an effective therapy for diabetic mice. Here we attempted…”
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Using size‐controlled multicellular spheroids of murine adenocarcinoma cells to efficiently establish pulmonary tumors in mice
Published in Biotechnology journal (01-08-2017)“…Previous studies demonstrated that multicellular spheroids developed using polydimethylsiloxane‐based microwells exhibited superior functions, such as insulin…”
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Longitudinal dynamic changes in factor VIII inhibitor titers in patients with hemophilia A and inhibitors receiving emicizumab prophylaxis
Published in International journal of hematology (01-12-2023)“…Emicizumab prophylaxis dramatically reduces bleeding events in patients with hemophilia A (PwHA) with or without factor VIII (FVIII) inhibitors. However,…”
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Poly(N-isopropylacrylamide)-coated microwell arrays for construction and recovery of multicellular spheroids
Published in Journal of bioscience and bioengineering (01-06-2013)“…Microwell arrays that have many micro-sized cavities on the device have been employed to form multicellular spheroids. However, methods to efficiently harvest…”
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