Search Results - "Mizuno, Dai"

The molecular mechanisms of zinc neurotoxicity and the pathogenesis of vascular type senile dementia by Mizuno, Dai, Kawahara, Masahiro

“…Zinc (Zn) is an essential trace element that is abundantly present in the brain. Despite its importance in normal brain functions, excess Zn is neurotoxic and…”
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Toxic Effects of Two Redox States of Thallium on Immortalised Hypothalamic GT1-7 Neuronal Cells by Mizuno, Dai, Kawahara, Masahiro, Konoha-Mizuno, Keiko, Ogawara, Terumasa, Hama, Ryoji, Yamazaki, Kentaro

“…Thallium (Tl), is a highly toxic heavy metal that exists in monovalent (Tl(I)) and trivalent (Tl(III)) ionic states. This study aimed to compare the toxicities…”
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The Role of Zinc in the Development of Vascular Dementia and Parkinson's Disease and the Potential of Carnosine as Their Therapeutic Agent by Mizuno, Dai, Kawahara, Masahiro, Konoha-Mizuno, Keiko, Hama, Ryoji, Ogawara, Terumasa

“…Synaptic zinc ions (Zn ) play an important role in the development of vascular dementia (VD) and Parkinson's disease (PD). In this article, we reviewed the…”
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Disruption of zinc homeostasis and the pathogenesis of senile dementia by Kawahara, Masahiro, Mizuno, Dai, Koyama, Hironari, Konoha, Keiko, Ohkawara, Susumu, Sadakane, Yutaka

“…Zinc (Zn) is an essential trace element that is abundantly present in the brain. Although Zn plays crucial roles in learning and memory, numerous studies have…”
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Protective activity of carnosine and anserine against zinc-induced neurotoxicity: a possible treatment for vascular dementia by Mizuno, Dai, Konoha-Mizuno, Keiko, Mori, Miwako, Sadakane, Yutaka, Koyama, Hironari, Ohkawara, Susumu, Kawahara, Masahiro

“…Carnosine (β-alanyl- l -histidine) is a small dipeptide with numerous beneficial effects, including the maintenance of the acid-base balance, antioxidant…”
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Induction of systemic and mucosal immunity and maintenance of its memory against influenza A virus by nasal vaccination using a new mucosal adjuvant SF-10 derived from pulmonary surfactant in young cynomolgus monkeys by Mizuno, Dai, Kimoto, Takashi, Sakai, Satoko, Takahashi, Etsuhisa, Kim, Hyejin, Kido, Hiroshi

“…Graphical abstract Intranasal vaccination of flu vaccine with mucosal adjuvant SF-10 in cynomolgus young monkeys induced effective mucosal and systemic…”
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Oral Clarithromycin Enhances Airway Immunoglobulin A (IgA) Immunity through Induction of IgA Class Switching Recombination and B-Cell-Activating Factor of the Tumor Necrosis Factor Family Molecule on Mucosal Dendritic Cells in Mice Infected with Influenza A Virus by TAKAHASHI, Etsuhisa, KATAOKA, Kosuke, INDALAO, Irene L, KONOHA, Keiko, FUJII, Kazuyuki, CHIDA, Junji, MIZUNO, Dai, FUJIHASHI, Kohtaro, KIDO, Hiroshi

“…OA  Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+…”
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Immunomodulator clarithromycin enhances mucosal and systemic immune responses and reduces re-infection rate in pediatric patients with influenza treated with antiviral neuraminidase inhibitors: a retrospective analysis by Shinahara, Wakako, Takahashi, Etsuhisa, Sawabuchi, Takako, Arai, Masaru, Hirotsu, Nobuo, Takasaki, Yoshio, Shindo, Shizuo, Shibao, Kyoko, Yokoyama, Takashi, Nishikawa, Kiyoshi, Mino, Masahiro, Iwaya, Minako, Yamashita, Yuji, Suzuki, Satoshi, Mizuno, Dai, Kido, Hiroshi

“…Treatment with antiviral neuraminidase inhibitors suppresses influenza viral replication and antigen production, resulting in marked attenuation of mucosal…”
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Involvement of trace elements in the pathogenesis of prion diseases by Mizuno, Dai, Koyama, Hironari, Ohkawara, Susumu, Sadakane, Yutaka, Kawahara, Masahiro

“…Prion diseases are progressive neurodegenerative diseases that are associated with conformational changes that convert normal cellular prion protein (PrP(C))…”
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Crosstalk between metals and neurodegenerative diseases by Kawahara, Masahiro, Mizuno, Dai

“…Trace elements including iron, zinc, copper, and manganese play essential roles in the maintenance of brain functions. Accumulating evidence suggests that…”
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Surfactant protein C is an essential constituent for mucosal adjuvanticity of Surfacten, acting as an antigen delivery vehicle and inducing both local and systemic immunity by Mizuno, Dai, Kimoto, Takashi, Takei, Tsunetomo, Fukuta, Akiho, Shinahara, Wakako, Takahashi, Etsuhisa, Yano, Mihiro, Kido, Hiroshi

“…Graphical abstract…”
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Evaluation of nasal IgA secretion in normal subjects by nasal spray and aspiration by Fujimoto, Chisa, Kido, Hiroshi, Sawabuchi, Takako, Mizuno, Dai, Hayama, Masaki, Yanagawa, Hiroaki, Takeda, Noriaki

“…Abstract Objective Nasal washing (NW) is a popular method for collecting human nasal lavage fluid. However, for NW the subject must be trained, and the method…”
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Enhancing Cytotoxicity of Tamoxifen Using Geranium Oil by Mizuno, Dai, Kawahara, Masahiro, Konoha-Mizuno, Keiko, Yamazaki, Kentaro

“…Aromatherapy and plant-based essential oils are widely used as complementary and alternative therapies for various symptoms, including anxiety, mild mood…”
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Nasal vaccines by Kido, Hiroshi, Mizuno, Dai, Takei, Tsunetomo

“…The nasal route for vaccination offers both mucosal and systemic immunity for the prophylaxis of respiratory diseases. In order to induce maximal protective…”
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Regulation of CYP2D expression in rat brain by toluene by Mizuno, Dai, Hiroi, Toyoko, Ng, Pohshing, Kishimoto, Wataru, Imaoka, Susumu, Funae, Yoshihiko

“…We investigated the expressional regulation of cytochrome P450 (CYP) 2D isoforms in rat brain by toluene. Toluene (10 mmol/kg) was injected intraperitoneally…”
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An In Vitro System Comprising Immortalized Hypothalamic Neuronal Cells (GT1–7 Cells) for Evaluation of the Neuroendocrine Effects of Essential Oils by Kawahara, Masahiro, Haneda, Toshihiro, Yamazaki, Kentaro, Mori, Miwako, Konoha-Mizuno, Keiko, Mizuno, Dai, Koyama, Hironari

“…Aromatherapy and plant-based essential oils are widely used as complementary and alternative therapies for symptoms including anxiety. Furthermore, it was…”
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Attenuation of inducible respiratory immune responses by oseltamivir treatment in mice infected with influenza A virus by Takahashi, Etsuhisa, Kataoka, Kosuke, Fujii, Kazuyuki, Chida, Junji, Mizuno, Dai, Fukui, Makoto, Hiro-O Ito, Fujihashi, Kohtaro, Kido, Hiroshi

“…The antiviral neuraminidase inhibitor oseltamivir (OSV) is widely used to suppress viral replication in the treatment of influenza. Here, we report that OSV…”
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Intranasal influenza vaccination using a new synthetic mucosal adjuvant SF‐10: induction of potent local and systemic immunity with balanced Th1 and Th2 responses by Kimoto, Takashi, Mizuno, Dai, Takei, Tsunetomo, Kunimi, Takuya, Ono, Shinji, Sakai, Satoko, Kido, Hiroshi

“…Background We found previously that bovine pulmonary Surfacten® used in newborns with acute respiratory distress syndrome is a safe and efficacious antigen…”
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Influenza vaccine with Surfacten, a modified pulmonary surfactant, induces systemic and mucosal immune responses without side effects in minipigs by Nishino, Maki, Mizuno, Dai, Kimoto, Takashi, Shinahara, Wakako, Fukuta, Akiho, Takei, Tsunetomo, Sumida, Kaori, Kitamura, Seiichiro, Shiota, Hiroshi, Kido, Hiroshi

“…Abstract Immune responses and side effects of intranasally administered flu vaccine with the commercial product Surfacten, a modified bovine pulmonary…”
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Modified Pulmonary Surfactant Is a Potent Adjuvant That Stimulates the Mucosal IgA Production in Response to the Influenza Virus Antigen by Mizuno, Dai, Ide-Kurihara, Mikiko, Ichinomiya, Tomoko, Kubo, Itsuka, Kido, Hiroshi

“…The intranasal administration of influenza hemagglutinin (HA) vaccine with Surfacten, a modified pulmonary surfactant free of antigenic c-type lectins, as a…”
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