Search Results - "Mizukami, Jun"

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  1. 1

    Lead generation and optimization of novel GPR119 agonists with a spirocyclic cyclohexane structure by Harada, Kazuhito, Mizukami, Jun, Watanabe, Takashi, Mori, Genki, Ubukata, Minoru, Suwa, Katsunori, Fukuda, Sumiaki, Negoro, Tamotsu, Sato, Motohide, Inaba, Takashi

    Published in Bioorganic & medicinal chemistry letters (01-02-2019)
    “…[Display omitted] We describe here the generation of a lead compound and its optimization studies that led to the identification of a novel GPR119 agonist…”
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  2. 2

    Design and synthesis of novel and potent GPR119 agonists with a spirocyclic structure by Harada, Kazuhito, Mizukami, Jun, Kadowaki, Sho, Matsuda, Isamu, Watanabe, Takashi, Oe, Yasuhiro, Kodama, Yoshitoshi, Aoki, Kenta, Suwa, Katsunori, Fukuda, Sumiaki, Yata, Shinji, Inaba, Takashi

    Published in Bioorganic & medicinal chemistry letters (15-04-2018)
    “…[Display omitted] Exploration of alternative structures of the substituted piperidine or piperazine ring which are characteristic in most of the reported…”
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  3. 3

    Optimization of oxadiazole derivatives with a spirocyclic cyclohexane structure as novel GPR119 agonists by Harada, Kazuhito, Mizukami, Jun, Watanabe, Takashi, Mori, Genki, Ubukata, Minoru, Suwa, Katsunori, Fukuda, Sumiaki, Negoro, Tamotsu, Sato, Motohide, Inaba, Takashi

    Published in Bioorganic & medicinal chemistry letters (15-08-2019)
    “…[Display omitted] We describe here a novel GPR119 agonist 24, which showed a potent and long-acting hypoglycemic effect in rats via oral dosing. For the…”
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  4. 4

    Synthesis of Helicenediamine Oligomers and Their Formation of Multilayer Structures in Aqueous Solvents by Mizukami, Jun, Sugiura, Hiroki, Yamaguchi, Masahiko, Mushiake, Kumiko

    Published in Bulletin of the Chemical Society of Japan (01-02-2006)
    “…Optically active polyamine oligomers containing three to six (P)-5,8-bis(aminomethyl)-1,12-dimethylbenzo[c]phenanthrenes were synthesized employing the…”
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