Search Results - "Mizuguchi, Takaha"
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Electro-osmotic trapping and compression of single DNA molecules while passing through a nanopore
Published in Analyst (London) (21-09-2019)“…Complicated DNA molecular behaviors exist during translocation into a nanopore because their large and coiled structure needs to unwind. In this work, we…”
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Multimodal Multiphoton Imaging of the Lipid Bilayer by Dye-Based Sum-Frequency Generation and Coherent Anti-Stokes Raman Scattering
Published in Analytical chemistry (Washington) (21-04-2020)“…Coherent anti-Stokes Raman scattering (CARS) imaging is widely used for imaging molecular vibrations inside cells and tissues. Lipid bilayers are potential…”
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Activatable Raman Probes Utilizing Enzyme-Induced Aggregate Formation for Selective Ex Vivo Imaging
Published in Journal of the American Chemical Society (26-04-2023)“…Detecting multiple enzyme activities simultaneously with high spatial specificity is a promising strategy to investigate complex biological phenomena, and…”
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Monitoring the morphological evolution of giant vesicles by azo dye-based sum-frequency generation (SFG) microscopy
Published in Colloids and surfaces, B, Biointerfaces (01-02-2020)“…[Display omitted] •Used dye-based SFG imaging to monitor the morphological evolution of GVs.•This imaging provided images of the outer and inner faces of lipid…”
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Imaging the uptake of deuterated methionine in Drosophila with stimulated Raman scattering
Published in Frontiers in chemistry (29-03-2023)“…Visualizing small individual biomolecules at subcellular resolution in live cells and tissues can provide valuable insights into metabolic activity in…”
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High-Resolution Plasma Membrane-Selective Imaging by Second Harmonic Generation
Published in iScience (30-11-2018)“…The plasma membrane is the site of intercellular communication and subsequent intracellular signal transduction. The specific visualization of the plasma…”
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Super-resolution vibrational imaging based on photoswitchable Raman probe
Published in Science advances (16-06-2023)“…Super-resolution vibrational microscopy is promising to increase the degree of multiplexing of nanometer-scale biological imaging because of the narrower…”
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Applications of second harmonic generation (SHG)/sum-frequency generation (SFG) imaging for biophysical characterization of the plasma membrane
Published in Biophysical reviews (27-10-2020)“…The plasma membrane is a lipid bilayer of < 10 nm width that separates intra- and extra-cellular environments and serves as the site of cell-cell…”
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Wide Dynamic Range Detection of Target DNA by Single Particle Microscopy of DNA-Gold Nanoparticle Multimers
Published in Biophysical journal (07-02-2020)Get full text
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Plasma Membrane-Selective Visualization by Multimodal Two-Photon Imaging in Living Cells using Second Harmonic Generation
Published in Biophysical journal (15-02-2019)Get full text
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Visualization of Modified Bisarylbutadiyne-Tagged Small Molecules in Live-Cell Nuclei by Stimulated Raman Scattering Microscopy
Published in Analytical chemistry (Washington) (30-04-2024)“…Visualizing the distribution of small-molecule drugs in living cells is an important strategy for developing specific, effective, and minimally toxic drugs. As…”
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Three-Dimensional Analysis of Water Dynamics in Human Skin by Stimulated Raman Scattering
Published in The journal of physical chemistry. B (08-06-2023)“…The stratum corneum (SC), the outermost layer of the skin, has an important function to provide a barrier against dry environments. To evaluate the barrier…”
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Widely tunable fiber optical parametric oscillator synchronized with a Ti:sapphire laser for stimulated Raman scattering microscopy
Published in Biomedical optics express (01-05-2024)“…Stimulated Raman scattering (SRS) microscopy is a powerful vibrational imaging technique with high chemical specificity. However, the insufficient tuning range…”
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Stimulated Raman Scattering Microscopy with a Widely Tunable Fiber Optical Parametric Oscillator and Ti:Sapphire Laser
Published in 2024 Conference on Lasers and Electro-Optics (CLEO) (05-05-2024)“…We present a widely tunable fiber optical parametric oscillator with a tuning range of 1470 cm −1 . By synchronizing it with a Ti:sapphire laser, we succeed in…”
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