Search Results - "Mizrahi, Mark"
-
1
α1-Antitrypsin Monotherapy Induces Immune Tolerance during Islet Allograft Transplantation in Mice
Published in Proceedings of the National Academy of Sciences - PNAS (21-10-2008)“…Human pancreatic islet transplantation offers diabetic patients tight glucose control but has low graft survival rates. The immunosuppressive drugs that are…”
Get full text
Journal Article -
2
Nitric oxide charged catheters as a potential strategy for prevention of hospital acquired infections
Published in PloS one (14-04-2017)“…Catheter-Associated Hospital-Acquired Infections (HAI's) are caused by biofilm-forming bacteria. Using a novel approach, we generated anti-infective barrier on…”
Get full text
Journal Article -
3
Acute Phase Protein α₁-Antitrypsin Reduces the Bacterial Burden in Mice by Selective Modulation of Innate Cell Responses
Published in The Journal of infectious diseases (01-05-2015)“…Background. Severe bacterial infection can cause sepsis, multiple organ dysfunction syndrome (MODS), and death. Human α₁-antitrypsin (hAAT) is an…”
Get full text
Journal Article -
4
CS1-6 Protection of insulin producing beta cells by the anti-inflammatory acute phase protein alpha-1- antitrypsin
Published in Cytokine (Philadelphia, Pa.) (01-10-2010)Get full text
Journal Article -
5
Human α1-Antitrypsin Binds to Heat-Shock Protein gp96 and Protects from Endogenous gp96-Mediated Injury In vivo
Published in Frontiers in immunology (2013)“…The extracellular form of the abundant heat-shock protein, gp96, is involved in human autoimmune pathologies. In patients with type 1 diabetes, circulating…”
Get full text
Journal Article -
6
α-1 antitrypsin promotes semimature, IL-10-producing and readily migrating tolerogenic dendritic cells
Published in The Journal of immunology (1950) (01-07-2012)“…Tolerogenic IL-10-positive CCR7-positive dendritic cells (DC) promote T regulatory (Treg) cell differentiation upon CCR7-dependent migration to draining lymph…”
Get full text
Journal Article -
7
alpha 1-Antitrypsin monotherapy induces immune tolerance during islet allograft transplantation in mice
Published in Proceedings of the National Academy of Sciences - PNAS (21-10-2008)“…Human pancreatic islet transplantation offers diabetic patients tight glucose control but has low graft survival rates. The immunosuppressive drugs that are…”
Get full text
Journal Article -
8
α-1-antitrypsin gene delivery reduces inflammation, increases T-regulatory cell population size and prevents islet allograft rejection
Published in Molecular medicine (Cambridge, Mass.) (01-09-2011)“…Antiinflammatory clinical-grade, plasma-derived human α-1 antitrypsin (hAAT) protects islets from allorejection as well as from autoimmune destruction. hAAT…”
Get full text
Journal Article -
9
Human α1-antitrypsin attenuates injury-induced Inflammation through interacting with high mobility group box-1 (HMGB1)
Published in The Journal of immunology (1950) (01-05-2017)“…HMGB1 is involved in pathologies such as cellular injury and autoimmunity. Indeed, upon binding to immune-related receptors, HMGB1 promotes an inflammatory…”
Get full text
Journal Article -
10
Human α1‐antitrypsin modifies B‐lymphocyte responses during allograft transplantation
Published in Immunology (01-11-2013)“…Summary B‐lymphocyte activities are associated with allograft rejection. Interleukin‐10 (IL‐10) ‐expressing B cells, however, exhibit regulatory attributes…”
Get full text
Journal Article -
11
Human alpha 1-antitrypsin modifies B-lymphocyte responses during allograft transplantation
Published in Immunology (01-11-2013)“…B-lymphocyte activities are associated with allograft rejection. Interleukin-10 (IL-10) -expressing B cells, however, exhibit regulatory attributes. Human…”
Get full text
Journal Article -
12
Nitric Oxide Charged Catheters as a Potential Strategy for Prevention of Hospital Acquired Infections
Published in Open forum infectious diseases (01-12-2016)Get full text
Journal Article -
13
PS2-032. Human α1-Antitrypsin Blocks Inflammation Induced by High mobility Group Box-1 (HMGB1) in Pancreatic Islets
Published in Cytokine (Philadelphia, Pa.) (01-10-2011)Get full text
Journal Article -
14
CS06-6. Human Alpha 1 Antitrypsin Modulates B lymphocyte Responses in Culture and During Allogeneic Transplantation
Published in Cytokine (Philadelphia, Pa.) (01-10-2011)Get full text
Journal Article -
15
PS2-032. Human [alpha]1-Antitrypsin Blocks Inflammation Induced by High mobility Group Box-1 (HMGB1) in Pancreatic Islets
Published in Cytokine (Philadelphia, Pa.) (01-10-2011)Get full text
Journal Article -
16
Human [alpha]1-antitrypsin modifies B-lymphocyte responses during allograft transplantation
Published in Immunology (01-11-2013)“…Summary B-lymphocyte activities are associated with allograft rejection. Interleukin-10 (IL-10) -expressing B cells, however, exhibit regulatory attributes…”
Get full text
Journal Article -
17
Potential for Unintended Consequences in an Ecuadorian Hook Exchange Program
Published 01-01-2012“…The central question of this case study asks if circle hook use in Ecuador is motivated by a desire to catch more sharks. Circle hooks are a conservation…”
Get full text
Dissertation -
18
In Vivo Introduction of an Extrachromosomal Plasmid Expressing Long-term Human Alpha-1-antitrypsin protects Islet Allografts (141.48)
Published in The Journal of immunology (1950) (01-04-2009)“…Alpha-1-antitrypsin (AAT) exerts anti-inflammatory and tolerogenic activities during islet allograft transplantation in diabetes mouse models. Although a…”
Get full text
Journal Article -
19
PS2-14 Inhibition of the heat shock protein GP96 modulates inflammatory processes during islet transplantation
Published in Cytokine (Philadelphia, Pa.) (01-10-2010)Get full text
Journal Article -
20
Protection of islet allografts by in vivo introduction of an extrachromosomal plasmid expressing human alpha-1-antitrypsin
Published in Cytokine (Philadelphia, Pa.) (01-10-2009)Get full text
Journal Article