Search Results - "Mizrachi, Tehila"

Neuroinflammation Modulation via α7 Nicotinic Acetylcholine Receptor and Its Chaperone, RIC-3 by Mizrachi, Tehila, Vaknin-Dembinsky, Adi, Brenner, Talma, Treinin, Millet

“…Nicotinic acetylcholine receptors (nAChRs) are widely expressed in or on various cell types and have diverse functions. In immune cells nAChRs regulate…”
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Suppression of neuroinflammation by an allosteric agonist and positive allosteric modulator of the α7 nicotinic acetylcholine receptor GAT107 by Mizrachi, Tehila, Marsha, Oshrit, Brusin, Karen, Ben-David, Yael, Thakur, Ganesh A, Vaknin-Dembinsky, Adi, Treinin, Millet, Brenner, Talma

“…The α7 nicotinic acetylcholine receptor (α7 nAChR) negatively regulates the synthesis and release of pro-inflammatory cytokines by immune cells. Our previous…”
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NMO-IgG and AQP4 Peptide Can Induce Aggravation of EAMG and Immune-Mediated Muscle Weakness by Vaknin-Dembinsky, Adi, Brenner, Talma, Karussis, Dimitrios, Zur, Mayan, Fellig, Y., Nevo, Yoram, Rabie, Malcolm, Brill, Livnat, Mizrachi, Tehila, Oded, Abramsky

“…Neuromyelitis optica (NMO) and myasthenia gravis (MG) are autoimmune diseases mediated by autoantibodies against either aquaporin 4 (AQP4) or acetylcholine…”
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Role of tissue plasminogen activator in clinical aggravation of experimental autoimmune encephalomyelitis and its therapeutic potential by Mizrachi, Tehila, Gur-Wahnon, Devorah, Al-Roof Higazi, Abd, Brenner, Talma

“…•Tissue plasminogen activator (tPA) has immunomodulatory effect in EAE.•Absence of tPA aggravate EAE, while administration of tPA ameliorate the…”
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MicroRNA signature associated with treatment response in myasthenia gravis: A further step towards precision medicine by Cavalcante, Paola, Mizrachi, Tehila, Barzago, Claudia, Scandiffio, Letizia, Bortone, Federica, Bonanno, Silvia, Frangiamore, Rita, Mantegazza, Renato, Bernasconi, Pia, Brenner, Talma, Vaknin-Dembinsky, Adi, Antozzi, Carlo

“…[Display omitted] Myasthenia gravis (MG) is an autoimmune disorder affecting neuromuscular transmission currently treated with chronic immunosuppression…”
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Suppression of neuroinflammation by an allosteric agonist and positive allosteric modulator of the [alpha]7 nicotinic acetylcholine receptor GAT107 by Mizrachi, Tehila, Marsha, Oshrit, Brusin, Karen, Ben-David, Yael, Thakur, Ganesh A, Vaknin-Dembinsky, Adi, Treinin, Millet, Brenner, Talma

“…Background The [alpha]7 nicotinic acetylcholine receptor ([alpha]7 nAChR) negatively regulates the synthesis and release of pro-inflammatory cytokines by…”
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RIC-3 expression and splicing regulate nAChR functional expression by Ben-David, Yael, Mizrachi, Tehila, Kagan, Sarah, Krisher, Tamar, Cohen, Emiliano, Brenner, Talma, Treinin, Millet

“…The nicotinic acetylcholine receptors form a large and diverse family of acetylcholine gated ion channels having diverse roles in the central nervous system…”
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The plasminogen activator system: involvement in central nervous system inflammation and a potential site for therapeutic intervention by Gur-Wahnon, Devorah, Mizrachi, Tehila, Maaravi-Pinto, Florence-Yehudith, Lourbopoulos, Athanasis, Grigoriadis, Nikolaos, Higazi, Abd-Al Roof, Brenner, Talma

“…Extracellular proteases such as plasminogen activators (PAs) and matrix metalloproteinases modulate cell-cell and cell-matrix interactions. Components of the…”
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Tissue plasminogen activator involvement in experimental autoimmune myasthenia gravis: Aggravation and therapeutic potential by Gur-Wahnon, Devorah, Mizrachi, Tehila, Wald-Altman, Shane, Higazi, Abd Al-Roof, Brenner, Talma

“…Abstract Tissue plasminogen activator (tPA), a component of the PA/plasmin system, is elevated in inflammatory areas and plays a role in inflammatory…”
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B-cell markers from the BAFF family as predictors for experimental autoimmune myasthenia gravis aggravation in mice lacking plasminogen activator components by Brenner, Talma, Mizrachi, Tehila, Gur-Wahnon, Devorah, Sicsic, Camille, Higazi, Abd Al-Roof

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Amelioration of autoimmune neuroinflammation by the fusion molecule Fn14·TRAIL by Prinz-Hadad, Hodaya, Mizrachi, Tehila, Irony-Tur-Sinai, Michal, Prigozhina, Tatyana B, Aronin, Alexandra, Brenner, Talma, Dranitzki-Elhalel, Michal

“…Multiple sclerosis (MS) is a, T cell-mediated autoimmune disease, the management of which remains challenging. The recently described fusion protein,…”
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Amelioration of autoimmune neuroinflammation by the fusion molecule Fn14TRAIL by Prinz-Hadad, Hodaya, Mizrachi, Tehila, Irony-Tur-Sinai, Michal, Prigozhina, Tatyana B, Aronin, Alexandra, Brenner, Talma, Dranitzki-Elhalel, Michal

“…Background Multiple sclerosis (MS) is a, T cell-mediated autoimmune disease, the management of which remains challenging. The recently described fusion…”
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