Search Results - "Mizrachi, E."

β-cell failure as a complication of diabetes by Chang-Chen, K. J., Mullur, R., Bernal-Mizrachi, E.

“…Type 2 diabetes mellitus is a complex disease characterized by β -cell failure in the setting of insulin resistance. In early stages of the disease, pancreatic…”
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Temporal analysis of Arabidopsis genes activated by Eucalyptus grandis NAC transcription factors associated with xylem fibre and vessel development by Laubscher, M., Brown, K., Tonfack, L. B., Myburg, A. A., Mizrachi, E., Hussey, S. G.

“…Secondary cell wall (SCW) deposition in Arabidopsis is regulated among others by NAC transcription factors, where SND1 chiefly initiates xylem fibre…”
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Mice with beta cell overexpression of glycogen synthase kinase-3β have reduced beta cell mass and proliferation by Liu, Z., Tanabe, K., Bernal-Mizrachi, E., Permutt, M. A.

“…Aims/hypothesis Glycogen synthase kinase-3 (GSK3) has been implicated in the pathophysiology of several prevalent diseases, including diabetes. However,…”
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Mice conditionally lacking the Wolfram gene in pancreatic islet beta cells exhibit diabetes as a result of enhanced endoplasmic reticulum stress and apoptosis by RIGGS, A. C, BERNAL-MIZRACHI, E, OHSUGI, M, WASSON, J, FATRAI, S, WELLING, C, MURRAY, J, SCHMIDT, R. E, HERRERA, P. L, PERMUTT, M. A

“…Wolfram syndrome is an autosomal recessive disorder characterised by childhood diabetes mellitus, optic atrophy and severe neurodegeneration, resulting in…”
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Regulation of β-cell mass and function by the Akt/protein kinase B signalling pathway by Elghazi, L, Rachdi, L, Weiss, A.J, Cras-Méneur, C, Bernal-Mizrachi, E

“…The insulin receptor substrate-2/phosphoinositide 3-kinase (PI3K) pathway plays a critical role in the regulation of β-cell mass and function, demonstrated…”
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Islet beta cell expression of constitutively active Akt1/PKB alpha induces striking hypertrophy, hyperplasia, and hyperinsulinemia by Bernal-Mizrachi, E, Wen, W, Stahlhut, S, Welling, C M, Permutt, M A

“…The phosphoinositide 3-kinase-Akt/PKB pathway mediates the mitogenic effects various nutrients and growth factors in cultured cells. To study its effects in…”
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Influence of stereochemistry in the macrocyclic tetrapeptide CJ-15,208 on antinociceptive efficacy and opioid receptor selectivity by Eans, S.O, Ganno, M.L, Mizrachi, E, Senadheera, S.N, Aldrich, J, McLaughlin, J.P

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Development of mixed opioid agonist/antagonists to prevent reinstatement of extinguished cocaine-seeking behavior by Eans, S.O, Ganno, M.L, Mizrachi, E, Senadheera, S, Aldrich, J.V, McLaughlin, Jay P

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Enhanced beta cell proliferation in mice overexpressing a constitutively active form of Akt and one allele of p21Cip by Blandino-Rosano, M., Alejandro, E. U., Sathyamurthy, A., Scheys, J. O., Gregg, B., Chen, A. Y., Rachdi, L., Weiss, A., Barker, D. J., Gould, A. P., Elghazi, L., Bernal-Mizrachi, E.

“…Aims/hypothesis The ability of pancreatic beta cells to proliferate is critical both for normal tissue maintenance and in conditions where there is an…”
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Activation of Serum Response Factor in the Depolarization Induction of Egr-1 Transcription in Pancreatic Islet β-Cells by Bernal-Mizrachi, Ernesto, Wice, Burton, Inoue, Hiroshi, Permutt, M. Alan

“…The results of the current studies define the major elements whereby glucose metabolism in islet β-cells leads to transcriptional activation of an early…”
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An expression profile of human pancreatic islet mRNAs by Serial Analysis of Gene expression (SAGE) by CRAS-MENEUR, C, INOUE, H, ZHOU, Y, OHSUGI, M, BERNAL-MIZRACHI, E, PAPE, D, CLIFTON, S. W, PERMUTT, M. A

“…The Human Genome Project seeks to identify all genes with the ultimate goal of evaluation of relative expression levels in physiology and in disease states…”
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Glucose and other insulin secretagogues induce, rather than inhibit, expression of Id-1 and Id-3 in pancreatic islet beta cells by WICE, B. M, BERNAL-MIZRACHI, E, PERMUTT, M. A

“…Basic helix loop helix transcription factors regulate insulin gene transcription. Therefore, molecules that regulate their function should affect insulin…”
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Enhanced beta cell proliferation in mice overexpressing a constitutively active form of Akt and one allele of p21 Cip by Blandino-Rosano, M., Alejandro, E. U., Sathyamurthy, A., Scheys, J. O., Gregg, B., Chen, A. Y., Rachdi, L., Weiss, A., Barker, D. J., Gould, A. P., Elghazi, L., Bernal-Mizrachi, E.

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9343 Protection Against Type 1 Diabetes Development In Mice With 4E-BP2 Deletion by Pita Grisanti, V, Pecanha, F, Louzada, R, Blandino, M, Jaramillo, C, Arenas, N, Bayer, A, Bernal-Mizrachi, E

“…Abstract Disclosure: V. Pita Grisanti: None. F. Pecanha: None. R. Louzada: None. M. Blandino: None. C. Jaramillo: None. N. Arenas: None. A. Bayer: None. E…”
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Increased dosage of mammalian Sir2 in pancreatic β cells enhances glucose-stimulated insulin secretion in mice by Moynihan, Kathryn A., Grimm, Andrew A., Plueger, Marie M., Bernal-Mizrachi, Ernesto, Ford, Eric, Cras-Méneur, Corentin, Permutt, M. Alan, Imai, Shin-ichiro

“…Sir2 NAD-dependent deacetylases connect transcription, metabolism, and aging. Increasing the dosage or activity of Sir2 extends life span in yeast, worms, and…”
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Inferring secondary cell wall-associated transcriptional regulatory networks in Eucalyptus grandis through high-throughput DNA affinity purification sequencing by Takawira, L.T., Mizrachi, E., Myburg, A.A., Hussey, S.G.

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Development of CRISPR gene editing constructs for use in woody plants by Maloney, V.J., Lloyd, D., Wierzbicki, M., Mizrachi, E., Myburg, A.A.

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The data acquisition system of the LZ dark matter detector: FADR by Aalbers, J., Al Musalhi, A.K., Amarasinghe, C.S., Araújo, H.M., Armstrong, J.E., Baker, A., Balashov, S., Bang, J., Beattie, K., Boxer, B., Brew, C.A.J., Brás, P., Buckley, J.H., Burdin, S., Carmona-Benitez, M.C., Chin, Y.T., Cottle, A., Cox, G., Curran, D., Dahl, C.E., David, A., de Viveiros, L., Dimino, T., Dobson, J.E.Y., Fiorucci, S., Fraser, E.D., Fruth, T.M.A., Geffre, A., Gelfand, R., Ghag, C., Gokhale, S., van der Grinten, M.G.D., Haiston, J.J., Hall, C.R., Han, S., James, R.S., Kamaha, A.C., Khaitan, D., Khazov, A., Khurana, I., Kim, J., Kingston, J., Kodroff, D., Korley, L., Leonard, D.S., Lesko, K.T., Levy, C., Lorenzon, W., Majewski, P.A., Manalaysay, A., Mannino, R.L., McDowell, G., McLaughlin, J., McMonigle, R., Mizrachi, E., Monzani, M.E., Moongweluwan, M., Morrison, E., Mount, B.J., Murdy, M., Neves, F., Nikoleyczik, J.A., Olevitch, M.A., Oliver-Mallory, K.C., Orpwood, J., Palmer, J., Pannifer, N.J., Pereira, G., Pershing, T., Piepke, A., Reichenbacher, J., Rhyne, C.A., Riyat, H.S., Rushton, T., Schnee, R.W., Shaw, S., Silva, C., Siniscalco, J., Skulski, W., Smith, R., Solovov, V.N., Sorensen, P., Soria, J., Stancu, I., Sumner, T.J., Szydagis, M., Timalsina, M., Tovey, D.R., Tranter, J., Tripathi, M., Vacheret, A., Vaitkus, A.C., Valentino, O., Watson, J.R., Williams, M., Wolfs, J.D., Wright, C.J., Xia, Q., Xiang, X., Yin, J.

“…The Data Acquisition System (DAQ) for the LUX-ZEPLIN (LZ) dark matter detector is described. The signals from 745 PMTs, distributed across three subsystems,…”
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The evolution of secondary xylem in angiosperms and its loss in monocots by Roodt, D., Li, Z., Van de Peer, Y., Mizrachi, E.

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Identification of radiopure titanium for the LZ dark matter experiment and future rare event searches by Akerib, D.S., Arnquist, I.J., Bai, X., Belle, J., Beltrame, P., Bernard, E.P., Biesiadzinski, T.P., Boast, K.E., Bolozdynya, A., Boxer, B., Bramante, R., Brás, P., Buckley, J.H., Busenitz, J.K., Carlson, B., Cherwinka, J.J., Chiller, A.A., Chiller, C., Craddock, W.W., Dahl, C.E., Davison, T.J.R., Dobson, J.E.Y., Druszkiewicz, E., Edwards, W.R., Emmet, W.T., Faham, C.H., Gaitskell, R.J., Gehman, V.M., Gerhard, R.M., Ghag, C., Gilchriese, M.G.D., Gomber, B., Haselschwardt, S.J., Hertel, S.A., Hillbrand, S., Hjemfelt, C., Hoppe, E.W., Hor, J.Y-K., Huang, D.Q., Hurteau, T.W., Ignarra, C.M., Kamdin, K., Khaitan, D., Khromov, A.V., Konovalov, A.M., Kudryavtsev, V.A., Kyre, S., Lee, C., Lesko, K.T., Lippincott, W.H., Lopez Paredes, B., Lorenzon, W., Manalaysay, A., Mei, D.-M., Miller, E.H., Mizrachi, E., Mock, J., Monzani, M.E., O’Dell, J., O’Sullivan, K., Oliver-Mallory, K.C., Palladino, K.J., Piepke, A., Preece, R.M., Pushkin, K., Ratcliff, B.N., Reichenbacher, J., Richards, A., Rodrigues, J.P., Rosero, R., Schnee, R.W., Schubnell, M., Skarpaas, K., Solovov, V.N., Sorensen, P., Stancu, I., Stark, M.R., Stephenson, S., Stiegler, T.M., Stifter, K., Sumner, T.J., Taylor, W.C., Temples, D., Thomas, K.J., To, W.H., Tripathi, M., Va’vra, J., van der Grinten, M.G.D., Verbus, J.R., Vuosalo, C.O., Waldron, W.L., Wang, R., Watson, R., Webb, R.C., Wei, W.-Z., While, M., Wolfs, F.L.H., Worm, S., Yeh, M., Yin, J.

“…The LUX-ZEPLIN (LZ) experiment will search for dark matter particle interactions with a detector containing a total of 10 tonnes of liquid xenon within a…”
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