Search Results - "Mizon, Charlotte"
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1
Human pre-α-inhibitor: isolation from a by-product of industrial scale plasma fractionation and structural analysis of its H3 heavy chain
Published in Journal of chromatography. B, Biomedical sciences and applications (09-05-1997)“…Pre-α-inhibitor (PαI) is a serine proteinase inhibitor from human plasma. It comprises bikunin (BK) responsible for antiprotease activity, covalently linked to…”
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2
The major human urinary trypsin inhibitor is a proteoglycan
Published in European journal of biochemistry (15-07-1986)“…The major urinary trypsin inhibitor (Mr 44000), isolated from human urine, contains 35% carbohydrate. In addition to N‐acetylglucosamine and neutral sugars…”
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3
In acute inflammation, the chondroitin-4 sulphate carried by bikunin is not only longer; it is also undersulphated
Published in Biochimie (01-01-2003)“…Bikunin (Bk) is a Künitz-type serine proteinase inhibitor, which occurs in human plasma, mainly as covalent complexes with one or two of the three peptide…”
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4
The effect of the glycosaminoglycan chain removal on some properties of the human urinary trypsin inhibitor
Published in Biological chemistry Hoppe-Seyler (01-01-1987)“…The major urinary trypsin inhibitor UTI I is a proteoglycan. UTI c (Mr 26,000), produced by chrondroitin lyase digestion of UTI I, was isolated and…”
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5
Urinary bikunin determination provides insight into proteinase/proteinase inhibitor imbalance in patients with inflammatory diseases
Published in Clinical chemistry and laboratory medicine (01-06-2002)“…Bikunin (BK) is a Kunitz-type proteinase inhibitor responsible for most of the antitryptic activity of urine and so is known as the urinary trypsin inhibitor…”
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6
A chondroitin-sulfate chain is located on serine-10 of the urinary trypsin inhibitor
Published in International journal of biochemistry (1991)“…1. The glycopeptide carrying the glycosaminoglycan chain of the urinary trypsin inhibitor (immunologically and structurally related to inter-alpha-trypsin…”
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7
Effects of inter-α-inhibitor in experimental endotoxic shock and disseminated intravascular coagulation
Published in American journal of respiratory and critical care medicine (01-12-1997)“…We investigated the effects of human inter-alpha-inhibitor (I alpha I) on hemodynamics, oxygenation, and coagulation parameters in a porcine model of endotoxic…”
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8
The chondroitin sulfate chain of bikunin‐containing proteins in the inter‐α‐inhibitor family increases in size in inflammatory diseases
Published in European journal of biochemistry (01-05-2001)“…Inter‐α‐inhibitor (IαI) and pre‐α‐inhibitor (PαI) are the main members of a set of multichain serine proteinase inhibitors. Present in human plasma, they may…”
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9
Unmasking a hyaluronan‐binding site of the BX 7 B type in the H3 heavy chain of the inter‐α‐inhibitor family
Published in European journal of biochemistry (01-02-2001)“…The inter‐α‐inhibitor (IαI) family gathers together several plasma protease inhibitors such as IαI and pre‐α‐inhibitor (PαI) that are variously assembled from…”
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10
Inter-alpha-inhibitor (IalphaI) concentration in pig plasma is independent of acute phase protein response
Published in Clinical chemistry and laboratory medicine (01-05-1999)“…Human inter-alpha-inhibitor (IalphaI) has been shown to exert a beneficial therapeutic effect in a porcine model of endotoxin shock. It is therefore useful to…”
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11
Unmasking a hyaluronan‐binding site of the BX7B type in the H3 heavy chain of the inter‐α‐inhibitor family
Published in European journal of biochemistry (01-02-2001)“…The inter‐α‐inhibitor (IαI) family gathers together several plasma protease inhibitors such as IαI and pre‐α‐inhibitor (PαI) that are variously assembled from…”
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12
Oxidative inactivation of alpha 1-proteinase inhibitor by alveolar macrophages from healthy smokers requires the presence of myeloperoxidase
Published in American journal of respiratory cell and molecular biology (01-11-1991)“…The aim of this work was to study the ability of human alveolar macrophages (AM) of 10 healthy smokers to inactivate alpha 1-proteinase inhibitor (alpha 1PI)…”
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13
Disulphide bonds assignment in the inter‐α‐inhibitor heavy chains
Published in European journal of biochemistry (01-07-1998)“…Human inter‐α‐inhibitor (IαI) is a plasma serine‐proteinase inhibitor. It consists of three polypeptide chains covalently linked by a glycosaminoglycan : a…”
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14
Preparation and properties of a therapeutic inter-alpha-trypsin inhibitor concentrate from human plasma
Published in Vox sanguinis (01-01-1994)“…Inter-alpha-trypsin inhibitor (ITI) is a serine protease inhibitor found in human plasma. Its antiprotease activity is due to bikunin which is effective in…”
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15
Purification and characterization of pig inter- α-inhibitor and its constitutive heavy chains
Published in Biochimica et biophysica acta (07-03-1997)“…With the view of investigating the metabolism of inter- α-inhibitor, a plasma serine-proteinase inhibitor, in an animal model of inflammatory syndrome, we…”
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16
Decreased faecal exoglycosidase activities identify a subset of patients with active Crohn's disease
Published in Clinical science (1979) (01-10-1992)“…1. alpha 1-Proteinase inhibitor (alpha 1-antitrypsin) is excreted in a deglycosylated form (M(r) 38,000) in the faeces of healthy subjects and in patients with…”
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17
Disulphide bonds assignment in the inter-alpha-inhibitor heavy chains--structural and functional implications
Published in European journal of biochemistry (01-07-1998)“…Human inter-alpha-inhibitor (IalphaI) is a plasma serine-proteinase inhibitor. It consists of three polypeptide chains covalently linked by a…”
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18
Deglycosylation of alpha 1-proteinase inhibitor is impaired in the faeces of patients with active inflammatory bowel disease (Crohn's disease)
Published in Clinical science (1979) (01-05-1991)“…1. alpha 1-Proteinase inhibitor (alpha 1-antitrypsin) was excreted in the faeces of patients with inflammatory bowel disease in different molecular forms:…”
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19
The heavy chains of human plasma inter-alpha-trypsin inhibitor: their isolation, their identification by electrophoresis and partial sequencing. Differential reactivity with concanavalin A
Published in Biological chemistry Hoppe-Seyler (01-10-1992)“…Inter-alpha-trypsin inhibitor (ITI) is a complex protein made up of a light chain so-called bikunin and two heavy chains (apparent Mr values 96000 and 86000 in…”
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20
Crossed immunoelectrophoresis does not allow accurate determination of inter-alpha-trypsin inhibitor and its derivatives in plasma
Published in Biological chemistry Hoppe-Seyler (01-09-1990)“…By crossed-immunoelectrophoresis (CIE) of plasma, using anti-inter-alpha-trypsin inhibitor (ITI) immunoglobulins, beside native ITI, related components are…”
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