Search Results - "Mizel, SB"

The interleukins by Mizel, S B

“…The interactions between immune and inflammatory cells are mediated in large part by proteins, termed interleukins (IL), that are able to promote cell growth,…”
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Flagellin Is an Effective Adjuvant for Immunization against Lethal Respiratory Challenge with Yersinia pestis by Honko, Anna N, Sriranganathan, Nammalwar, Lees, Cynthia J, Mizel, Steven B

“…Gram-negative flagellin, a Toll-like receptor 5 (TLR5) agonist, is a potent inducer of innate immune effectors such as cytokines and nitric oxide. In the lung,…”
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Mucosal Administration of Flagellin Induces Innate Immunity in the Mouse Lung by HONKO, Anna N, MIZEL, Steven B

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Effects of flagellin on innate and adaptive immunity by Honko, Anna N, Mizel, Steven B

“…Flagella are locomotive organelles present on a wide range of bacteria and are important for the pathogenesis of many species. Cells of the innate immune…”
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Induction of Macrophage Nitric Oxide Production by Gram-Negative Flagellin Involves Signaling Via Heteromeric Toll-Like Receptor 5/Toll-Like Receptor 4 Complexes by Mizel, Steven B, Honko, Anna N, Moors, Marlena A, Smith, Pameeka S, West, A. Phillip

“…The induction of cytokine synthesis by flagellin is mediated by a Toll-like receptor 5 (TLR5) signaling pathway. Although flagellin activation of the…”
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Gram-negative Flagellin-induced Self-tolerance Is Associated with a Block in Interleukin-1 Receptor-associated Kinase Release from Toll-like Receptor 5 by Mizel, Steven B., Snipes, James A.

“…Flagellin from a number of Gram-negative bacteria induces cytokine and nitric oxide production by inflammatory cell types. In view of the evidence that…”
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Identification of a Sequence in Human Toll-like Receptor 5 Required for the Binding of Gram-negative Flagellin by Mizel, Steven B, West, A Phillip, Hantgan, Roy R

“…Flagellins from Gram-negative bacteria activate inflammatory cells by a toll-like receptor 5 (TLR5)-dependent signaling pathway. We have examined the…”
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High-Affinity Interaction between Gram-Negative Flagellin and a Cell Surface Polypeptide Results in Human Monocyte Activation by MCDERMOTT, Patrick F, CIACCI-WOOLWINE, Federica, SNIPES, James A, MIZEL, Steven B

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Gangliosides Inhibit Flagellin Signaling in the Absence of an Effect on Flagellin Binding to Toll-like Receptor 5 by West, A. Phillip, Dancho, Brooke A., Mizel, Steven B.

“…A recent study (Ogushi, K., Wada, A., Niidome, T., Okuda, T., Llanes, R., Nakayama, M., Nishi, Y., Kurazono, H., Smith, K. D., Aderem, A., Moss, J., and…”
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Activation of Interleukin-1 Receptor-Associated Kinase by Gram-Negative Flagellin by MOORS, Marlena A, LIWU LI, MIZEL, Steven B

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Salmonella flagellin induces tumor necrosis factor alpha in a human promonocytic cell line by Ciacci-Woolwine, F, Blomfield, I.C, Richardson, S.H, Mizel, S.B

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Interleukin 1 and T cell activation by Mizel, S B

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mRNA and Protein Stability Regulate the Differential Expression of Pro- and Anti-inflammatory Genes in Endotoxin-tolerant THP-1 Cells by Learn, Chris A., Mizel, Steven B., McCall, Charles E.

“…The products of proinflammatory genes such as interleukin-1β (IL-1β) and cyclooxygenase-2 (COX-2) initiate many of the events associated with sepsis…”
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Induction of Cytokine Synthesis by Flagella from Gram-Negative Bacteria May Be Dependent on the Activation or Differentiation State of Human Monocytes by CIACCI-WOOLWINE, F, MCDERMOTT, P. F, MIZEL, S. B

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Proteasome-mediated regulation of interleukin-1β turnover and export in human monocytes by Moors, Marlena A., Mizel, Steven B.

“…Interleukin‐1β is a secreted protein that accumulates in the cytosol as an inactive precursor (pIL‐1β) before processing and release of biologically active…”
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Interleukin-1β Secretion. A POSSIBLE MULTISTEP PROCESS THAT IS REGULATED IN A CELL TYPE-SPECIFIC MANNER by Siders, William M., Mizel, Steven B.

“…In a prior study, we found that the processed form of human interleukin-1β (mature IL-1β) is secreted to a significantly greater extent than the precursor form…”
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Expression of interleukin-1α and β genes by human blood polymorphonuclear leukocytes by LORD, P. C. W, WILMOTH, L. M. G, MIZEL, S. B, MCCALL, C. E

“…Expression of IL-1 alpha and beta genes was studied in human blood PMN with close monitoring of the effects of contaminating mononuclear leukocytes (MNL). We…”
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Cyclic AMP--An Intracellular Second Messenger for Interleukin 1 by Shirakawa, Fumihiko, Yamashita, Uki, Chedid, Marcio, Mizel, Steven B.

“…We demonstrated that interleukin 1 (IL-1), a potent peptide mediator in immune and inflammatory responses, stimulates the synthesis of cAMP in a variety of…”
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Identification of a Membrane-Associated Interleukin 1 in Macrophages by Kurt-Jones, Evelyn A., Beller, David I., Mizel, Steven B., Unanue, Emil R.

“…We have found a surface membrane-associated interleukin 1 (IL-1) with potent thymocyte and T-cell stimulatory activity on peptone-elicited peritoneal…”
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Growth of a cloned helper T cell line induced by a monoclonal antibody specific for the antigen receptor: interleukin 1 is required for the expression of receptors for interleukin 2 by Kaye, J, Gillis, S, Mizel, SB, Shevach, EM, Malek, TR, Dinarello, CA, Lachman, LB, Janeway, CA, Jr

“…By using as an experimental system the induction of growth of a cloned, antigen:Ia-reactive helper T cell line by an antigen receptor-specific monoclonal…”
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