Search Results - "Mizdrak, Jasminka"

Tryptophan-derived ultraviolet filter compounds covalently bound to lens proteins are photosensitizers of oxidative damage by Mizdrak, Jasminka, Hains, Peter G., Truscott, Roger J.W., Jamie, Joanne F., Davies, Michael J.

“…The human eye is chronically exposed to light of wavelengths > 300 nm. In the young human lens, light of wavelength 300–400 nm is predominantly absorbed by the…”
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Detection, quantification, and total synthesis of novel 3-hydroxykynurenine glucoside-derived metabolites present in human lenses by Gad, Nicholas A, Mizdrak, Jasminka, Pattison, David I, Davies, Michael J, Truscott, Roger J W, Jamie, Joanne F

“…3-Hydroxykynurenine O-β-D-glucoside (3OHKG) protects the lens from UV damage, and novel related species may act analogously. The aim of this study was to…”
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Is protein methylation in the human lens a result of non-enzymatic methylation by S-adenosylmethionine? by Truscott, Roger J.W., Mizdrak, Jasminka, Friedrich, Michael G., Hooi, Michelle Y., Lyons, Brian, Jamie, Joanne F., Davies, Michael J., Wilmarth, Phillip A., David, Larry L.

“…Since crystallins in the human lens do not turnover, they are susceptible to modification by reactive molecules over time. Methylation is a major…”
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Novel human lens metabolites from normal and cataractous human lenses by Mizdrak, Jasminka, Hains, Peter G., Kalinowski, Danuta, Truscott, Roger J.W., Davies, Michael J., Jamie, Joanne F.

“…4-(2-Aminophenyl)-4-oxobutanoic acid, 4-(2-amino-3-hydroxyphenyl)-4-oxobutanoic acid and glutathionyl-kynurenine have been identified as novel metabolites in…”
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Role of Novel UV Filters in Human Lens Protein Damage Link to Age Related Nuclear Cataract by Gad, Nicholas, Mizdrak, Jasminka, Pattison, David, Davies, Michael, Truscott, Roger, Jamie, Joanne

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Is S-methylation in the human lens a result of non-enzymatic methylation by Sadenosylmethionine? by Truscott, Roger J.W., Mizdrak, Jasminka, Friedrich, Michael G., Hooi, Michelle Y., Lyons, Brian, Jamie, Joanne F., Davies, Michael J., Wilmarth, Philip A., David, Larry L.

“…Since crystallins in the human lens do not turnover, they are susceptible to modification by reactive molecules over time. Methylation is a major…”
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Identification of the new UV filter compound cysteine- l-3-hydroxykynurenine O-β- d-glucoside in human lenses by Hains, Peter G., Mizdrak, Jasminka, Streete, Isla M., Jamie, Joanne F., Truscott, Roger J.W.

“…UV filters protect the human lens and retina from UV light-induced damage. Here, we report the identification of a new UV filter, cysteine-…”
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Optimised expression and purification of recombinant human indoleamine 2,3-dioxygenase by Austin, Christopher J.D., Mizdrak, Jasminka, Matin, Azadeh, Sirijovski, Nicholche, Kosim-Satyaputra, Priambudi, Willows, Robert D., Roberts, Thomas H., Truscott, Roger J.W., Polekhina, Galina, Parker, Michael W., Jamie, Joanne F.

“…The hemoprotein indoleamine 2,3-dioxygenase (IDO) is the first and rate-limiting enzyme in mammalian tryptophan metabolism. It has received considerable…”
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