Search Results - "Miyoshi, Tomoichiro"

Human LINE-1 retrotransposons: impacts on the genome and regulation by host factors by Luqman-Fatah, Ahmad, Miyoshi, Tomoichiro

“…Genome sequencing revealed that nearly half of the human genome is comprised of transposable elements. Although most of these elements have been rendered…”
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Poly(ADP-Ribose) Polymerase 2 Recruits Replication Protein A to Sites of LINE-1 Integration to Facilitate Retrotransposition by Miyoshi, Tomoichiro, Makino, Takeshi, Moran, John V.

“…Long interspersed element-1 (LINE-1 or L1) retrotransposition poses a threat to genome integrity, and cells have evolved mechanisms to restrict…”
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Fission Yeast Pot1-Tpp1 Protects Telomeres and Regulates Telomere Length by Miyoshi, Tomoichiro, Kanoh, Junko, Saito, Motoki, Ishikawa, Fuyuki

“…Telomeres are specialized chromatin structures that protect chromosomal ends. Protection of telomeres 1 (Pot1) binds to the telomeric G-rich overhang, thereby…”
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A 3′ Poly(A) Tract Is Required for LINE-1 Retrotransposition by Doucet, Aurélien J., Wilusz, Jeremy E., Miyoshi, Tomoichiro, Liu, Ying, Moran, John V.

“…L1 retrotransposons express proteins (ORF1p and ORF2p) that preferentially mobilize their encoding RNA in cis, but they also can mobilize Alu RNA and, more…”
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Retrotransposon life cycle and its impacts on cellular responses by Luqman-Fatah, Ahmad, Nishimori, Kei, Amano, Shota, Fumoto, Yukiko, Miyoshi, Tomoichiro

“…Approximately 45% of the human genome is comprised of transposable elements (TEs), also known as mobile genetic elements. However, their biological function…”
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The interferon stimulated gene-encoded protein HELZ2 inhibits human LINE-1 retrotransposition and LINE-1 RNA-mediated type I interferon induction by Luqman-Fatah, Ahmad, Watanabe, Yuzo, Uno, Kazuko, Ishikawa, Fuyuki, Moran, John V., Miyoshi, Tomoichiro

“…Some interferon stimulated genes (ISGs) encode proteins that inhibit LINE-1 (L1) retrotransposition. Here, we use immunoprecipitation followed by liquid…”
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Author Correction: The interferon stimulated gene-encoded protein HELZ2 inhibits human LINE-1 retrotransposition and LINE-1 RNA-mediated type I interferon induction by Luqman-Fatah, Ahmad, Watanabe, Yuzo, Uno, Kazuko, Ishikawa, Fuyuki, Moran, John V., Miyoshi, Tomoichiro

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Dynamic transition of transcription and chromatin landscape during fission yeast adaptation to glucose starvation by Oda, Arisa, Takemata, Naomichi, Hirata, Yoshito, Miyoshi, Tomoichiro, Suzuki, Yutaka, Sugano, Sumio, Ohta, Kunihiro

“…Shortage of glucose, the primary energy source for all organisms, is one of the most critical stresses influencing cell viability. Glucose starvation promptly…”
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Local potentiation of stress-responsive genes by upstream noncoding transcription by Takemata, Naomichi, Oda, Arisa, Yamada, Takatomi, Galipon, Josephine, Miyoshi, Tomoichiro, Suzuki, Yutaka, Sugano, Sumio, Hoffman, Charles S, Hirota, Kouji, Ohta, Kunihiro

“…It has been postulated that a myriad of long noncoding RNAs (lncRNAs) contribute to gene regulation. In fission yeast, glucose starvation triggers lncRNA…”
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Fission yeast Ku protein is required for recovery from DNA replication stress by Miyoshi, Tomoichiro, Kanoh, Junko, Ishikawa, Fuyuki

“…The fundamental function of the conserved Ku70-Ku80 heterodimer is to promote the non-homologous end-joining (NHEJ) pathway in double-strand break repair…”
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Spatiotemporal regulation of meiotic recombination by Liaisonin by Miyoshi, Tomoichiro, Ito, Masaru, Ohta, Kunihiro

“…Sexual reproduction involves diversification of genetic information in successive generations. Meiotic recombination, which substantially contributes to the…”
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Human LINE-1 retrotransposons: impacts on the genome and regulation by host factors by Luqman-Fatah, Ahmad, Miyoshi, Tomoichiro

“…Genome sequencing revealed that nearly half of the human genome is comprised of transposable elements. Although most of these elements have been rendered…”
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Telomeric DNA Ends Are Essential for the Localization of Ku at Telomeres in Fission Yeast by Miyoshi, Tomoichiro, Sadaie, Mahito, Kanoh, Junko, Ishikawa, Fuyuki

“…The Ku70-Ku80 heterodimer is a conserved protein complex essential for the non-homologous end-joining pathway. Ku proteins are also involved in telomere…”
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1C-02 A central coupler for recombination initiation linking chromosome architecture to S-phase checkpoint by ITO Masaru, MIYOSHI Tomoichiro, KUGOU Kazuto, YAMADA Shintaro, FURUICHI Masaki, ODA Arisa, YAMADA Takatomi, HIROTA Kouji, MASAI Hisao, OHTA Kunihiro

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DHX36 maintains genomic integrity by unwinding G-quadruplexes by Mizumoto, Ayaka, Yokoyama, Yuta, Miyoshi, Tomoichiro, Takikawa, Masahiro, Ishikawa, Fuyuki, Sadaie, Mahito

“…The guanine-rich stretch of single-stranded DNA (ssDNA) forms a G-quadruplex (G4) in a fraction of genic and intergenic chromosomal regions. The probability of…”
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Stepwise chromatin remodelling by a cascade of transcription initiation of non-coding RNAs by Ohta, Kunihiro, Hirota, Kouji, Shibata, Takehiko, Kugou, Kazuto, Hoffman, Charles S, Miyoshi, Tomoichiro

“…Recent transcriptome analyses using high-density tiling arrays and data from large-scale analyses of full-length complementary DNA libraries by the FANTOM3…”
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A Central Coupler for Recombination Initiation Linking Chromosome Architecture to S Phase Checkpoint by Miyoshi, Tomoichiro, Ito, Masaru, Kugou, Kazuto, Yamada, Shintaro, Furuichi, Masaki, Oda, Arisa, Yamada, Takatomi, Hirota, Kouji, Masai, Hisao, Ohta, Kunihiro

“…Higher-order chromosome structure is assumed to control various DNA-templated reactions in eukaryotes. Meiotic chromosomes implement developed structures…”
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S9-2 THE EXTREME TERMINUS OF CHROMOSOMES by MIYOSHI Tomoichiro, SAITO Motoki, KANOH Junko, ISHIKAWA Fuyuki

“…The telomere is essential for protecting DNA ends from hazardous reactions, such as end-ligation and nucleolytic attack, and preventing excessive telomere…”
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Long-read sequencing identifies an SVA_D retrotransposon insertion deep within the intron of ATP7A as a novel cause of occipital horn syndrome by Yano, Naoko, Chong, Pin Fee, Kojima, Kenji K, Miyoshi, Tomoichiro, Luqman-Fatah, Ahmad, Kimura, Yu, Kora, Kengo, Kayaki, Taisei, Maizuru, Kanako, Hayashi, Takahiro, Yokoyama, Atsushi, Ajiro, Masahiko, Hagiwara, Masatoshi, Kondo, Teruyuki, Kira, Ryutaro, Takita, Junko, Yoshida, Takeshi

“…SINE-VNTR-Alu (SVA) retrotransposons move from one genomic location to another in a 'copy-and-paste' manner. They continue to move actively and cause monogenic…”
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Fission yeast Stn1 maintains stability of repetitive DNA at subtelomere and ribosomal DNA regions by Yamamoto, Io, Nakaoka, Hidenori, Takikawa, Masahiro, Tashiro, Sanki, Kanoh, Junko, Miyoshi, Tomoichiro, Ishikawa, Fuyuki

“…Telomere binding protein Stn1 forms the CST (Cdc13/CTC1-STN1-TEN1) complex in budding yeast and mammals. Likewise, fission yeast Stn1 and Ten1 form a complex…”
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