Search Results - "Miyazawa, Shuhei"

Synthesis of (S)-N-(endo -8-methyl-8-azabicyclo[3.2.1] oct-3α-yl)-4-amino-5-chloro-2-(1-methyl-2-butynyloxy) [carbonyl-14C]benzamide monohydrochloride (14C-E3620) by Hoshino, Yorihisa, Miyazawa, Shuhei, Nakata, Hiroshi, Etoh, Hironori, Furitsu, Mitsuko, Abe, Shinya

“…(S)‐N‐(endo‐8‐Methyl‐8‐azabicyclo[3.2.1]oct‐3α‐yl)‐4‐amino‐5‐chloro‐2‐(1‐methyl‐2‐butynyloxy)[carbonyl‐14C]benzamide monohydrochloride (14C‐E3620, 1 1), which…”
Get full text

E3710, a new proton pump inhibitor, with a long-lasting inhibitory effect on gastric acid secretion by Kodama, Kotaro, Fujisaki, Hideaki, Kubota, Atsuhiko, Kato, Hiroshi, Hirota, Kazuo, Kuramochi, Hiroko, Murota, Miki, Tabata, Yoshikuni, Ueda, Masato, Harada, Hitoshi, Kawahara, Tetsuya, Shinoda, Masanobu, Watanabe, Nobuhisa, Iida, Daisuke, Terauchi, Hiroki, Yasui, Sou, Miyazawa, Shuhei, Nagakawa, Junichi

“…We have investigated the pharmacology of sodium (R)-2-[4-(2,2-dimethyl-1,3-dioxan-5-yl) methoxy-3,5-dimethylpyridin-2-yl]methylsulfinyl-1H-benzimidazol…”
Get more information

Development of Radioimmunoassay for the Novel Platelet Activating Factor Receptor Antagonist, E6123, and Its Application to Pharmacokinetics in Laboratory Animals by KUSANO, Kazutomi, TADANO, Kyoichi, TANAKA, Shigeru, KAGEI, Yoshiko, UEDA, Masataka, MIYAZAWA, Shuhei, ABE, Yoshihisa, IDA, Satoshi, YUZURIHA, Teruaki

“…A direct radioimmunoassay for the determination of E6123, a novel antagonist of platelet activating factor (PAF) receptor, was developed in order to study the…”
Get full text

Hapten Synthesis for (+)-6-(2-Chlorophenyl)-3-cyclopropanecarbonyl-8,11-dimethyl-2,3,4,5-tetrahydro-8H-phyido(4',3':4,5)thieno(3,2-f)triazolo(4,3-a)(1,4)diazepine (E6123) by MIYAZAWA, Shuhei, OKANO, Kazuo, KAWAHARA, Tetsuya, MACHIDA, Yoshimasa, YAMATSU, Isao

Get full text

Structure-activity studies on triazolothienodiazepine derivatives as platelet-activating factor antagonists by Miyazawa, S, Okano, K, Shimomura, N, Clark, R S, Kawahara, T, Asano, O, Yoshimura, H, Miyamoto, M, Sakuma, Y, Muramoto, K

“…A series of triazolodiazepines was synthesized and evaluated for anti-platelet activating factor (PAF) activities. Structure-activity relationship (SAR)…”
Get full text

A Practical Synthesis of Optically Active Platelet-Activating Factor Antagonist, (+)-6-(2-Chlorophenyl)-3-cyclopropanecarbonyl-8,11-dimetyl-2,3,4,5-tetrahydro-8H-pyrido(4',3':4,5)thieno(3,2-f)(1,2,4)triazolo(4,3-a)(1,4)diazepine(E6123), and Its Absolute Configuration by MIYAZAWA, Shuhei, OKANO, Kazuo, SHIMOMURA, Naoyuki, KAWAHARA, Tetsuya, ASANO, Osamu, YOSHIMURA, Hiroyuki, KAWAI, Takatoshi, SOUDA, Shigeru, YOSHIDA, Yutaka, SATO, Tadashi, MACHIDA, Yoshimasa, YAMATSU, Isao

Get full text

Pharmacokinetic Studies of (S)-(+)-6-(2-chlorophenyl)-3-cyclopropanecarbonyl-8,11-dimethyl-2,3,4,5-tetrahydro-8H-pyrido(4',3':4,5)thieno(3,2-f)(1,2,4)triazolo(4,3-a)(1,4)diazepine (R6123). (I). Absorption, Distribution, Metabolism, Excretion and Identification of Metabolites in Beagle Dogs by KUSANO, Kazutomi, TANAKA, Shigeru, KOSAKI, Teruya, MIYAZAWA, Shuhei, TADANO, Kyoichi, YUZURIHA, Teruaki

Get full text

Hapten Synthesis for (+)-6-(2-Chlorophenyl)-3-cyclopropanecarbonyl-8, 11-dimethyl-2, 3, 4, 5-tetrahydro-8H-pyrido[4', 3' : 4, 5]thieno[3, 2-f]triazolo[4, 3-a][1, 4]diazepine(E6123) by MIYAZAWA, Shuhei, OKANO, Kazuo, KAWAHARA, Tetsuya, MACHIDA, Yoshimasa, YAMATSU, Isao

“…(+)-6-(2-Chlorophenyl)-3-cyclopropanecarbonyl-8, 11-dimethyl-2, 3, 4, 5-tetrahydro-8H-pyrido[4', 3' : 4, 5]thieno-[3, 2-f]triazolo[4, 3-a][1, 4]diazepine…”
Get full text

Hapten Synthesis for (+)-6-(2-Chlorophenyl)-3-cyclopropanecarbonyl-8, 11-dimethyl-2, 3, 4, 5-tetrahydro-8H-pyrido[4', 3' by MIYAZAWA, Shuhei, OKANO, Kazuo, KAWAHARA, Tetsuya, MACHIDA, Yoshimasa, YAMATSU, Isao

“…(+)-6-(2-Chlorophenyl)-3-cyclopropanecarbonyl-8, 11-dimethyl-2, 3, 4, 5-tetrahydro-8H-pyrido[4', 3' : 4, 5]thieno-[3, 2-f]triazolo[4, 3-a][1, 4]diazepine…”
Get full text

A Practical Synthesis of Optically Active Platelet-Activating Factor Antagonist, (+)-6-(2-Chlorophenyl)-3-cyclopropanecarbonyl-8, 11-dimethyl-2, 3, 4, 5-tetrahydro-8H-pyrido[4', 3' by MIYAZAWA, Shuhei, OKANO, Kazuo, SHIMOMURA, Naoyuki, KAWAHARA, Tetsuya, ASANO, Osamu, YOSHIMURA, Hiroyuki, KAWAI, Takatoshi, SOUDA, Shigeru, YOSHIDA, Yutaka, SATO, Tadashi, MACHIDA, Yoshimasa, YAMATSU, Isao

“…Optically active platelet-activating factor (PAF) receptor antagonist, (+)-6-(2-chlorophenyl)-3-cyclopropanecarbonyl-8, 11-dimethyl-2, 3, 4,…”
Get full text

A Practical Synthesis of Optically Active Platelet-Activating Factor Antagonist, (+)-6-(2-Chlorophenyl)-3-cyclopropanecarbonyl-8, 11-dimethyl-2, 3, 4, 5-tetrahydro-8H-pyrido[4', 3' : 4, 5]thieno[3, 2-f][1, 2, 4]triazolo[4, 3-a][1, 4]diazepine (E6123), and Its Absolute onfiguration by MIYAZAWA, Shuhei, OKANO, Kazuo, SHIMOMURA, Naoyuki, KAWAHARA, Tetsuya, ASANO, Osamu, YOSHIMURA, Hiroyuki, KAWAI, Takatoshi, SOUDA, Shigeru, YOSHIDA, Yutaka, SATO, Tadashi, MACHIDA, Yoshimasa, YAMATSU, Isao

“…Optically active platelet-activating factor (PAF) receptor antagonist, (+)-6-(2-chlorophenyl)-3-cyclopropanecarbonyl-8, 11-dimethyl-2, 3, 4,…”
Get full text

Structure-Activity Studies on Triazolothienodiazepine Derivaties as Platelet-Activating Factor Antagonists by MIYAZAWA, Shuhei, OKANO, Kazuo, SHIMOMURA, Naoyuki, CLARK, Richard S. J., KAWAHARA, Tesuya, ASANO, Osamu, YOSHIMURA, Hiroyuki, MIYAMOTO, Mituaki, SAKUMA, Yoshinori, MURAMOTO, Kenzo, OBAISHI, Hirosi, HARADA, Koukichi, KAJIMA, Takashi, YAMADA, Kouji, TSUNODA, Hajime, KATAYAMA, Satoshi, ABE, Shinya, ASAKAWA, Naoki, SOUDA, Shigeru, HORIE, Tohru, SATO, Tadashi, MACHIDA, Yoshimasa, KATAYAMA, Kouichi, YAMATSU, Isao

“…A series of triazolodiazepines was synthesized and evaluated for anti-platelet activating factor (PAF) activities. Structure-activity relationship (SAR)…”
Get full text