Search Results - "Miyazaki, Keiko"

Carbohydrate‐mediated cell adhesion in cancer metastasis and angiogenesis by Kannagi, Reiji, Izawa, Mineko, Koike, Tetsufumi, Miyazaki, Keiko, Kimura, Naoko

“…Malignant transformation is associated with abnormal glycosylation, resulting in the synthesis and expression of altered carbohydrate determinants including…”
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Altered expression of glycan genes in cancers induced by epigenetic silencing and tumor hypoxia: Clues in the ongoing search for new tumor markers by Kannagi, Reiji, Sakuma, Keiichiro, Miyazaki, Keiko, Lim, Khe‐Ti, Yusa, Akiko, Yin, Jun, Izawa, Mineko

“…(Cancer Sci 2010; 101: 586–593) The glycan molecules that preferentially appear in cancers are clinically utilized as serum tumor markers. The exact reason,…”
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Current relevance of incomplete synthesis and neo-synthesis for cancer-associated alteration of carbohydrate determinants—Hakomori's concepts revisited by Kannagi, Reiji, Yin, Jun, Miyazaki, Keiko, Izawa, Mineko

“…Incomplete synthesis and neo-synthesis are two major concepts for cancer-associated alterations of cell surface carbohydrate determinants, formulated by…”
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Long‐term flowering records of herbaceous plants in Tokyo, Japan, during 1994–2015 through citizen science by Maruyama, Noriko, Miyazaki, Keiko, Yasunaga, Eriko, Uchida, Kei, Kawabata, Saneyuki, Fukano, Yuya

“…We provide a 22‐year period (1994–2015) dataset of flowering records of herbaceous plant species in Tokyo, Japan. Trained volunteers of the citizen group…”
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Oral Administration of Okara Soybean By-Product Attenuates Cognitive Impairment in a Mouse Model of Accelerated Aging by Corpuz, Henry M, Arimura, Misa, Chawalitpong, Supatta, Miyazaki, Keiko, Sawaguchi, Makoto, Nakamura, Soichiro, Katayama, Shigeru

“…The microbiota-gut-brain axis has attracted increasing attention in the last decade. Here, we investigated whether okara, a soybean by-product rich in dietary…”
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Development of Pretreatment Protocols for Determination of Soybean β-Conglycinin in Processed Soybean Foods Using Commercial ELISA Kits by MORIYAMA, Tatsuya, YANO, Erika, ZAIMA, Nobuhiro, MIYAZAKI, Keiko, SHIROTSUKI, Kou, SATO, Aki, SAWAGUCHI, Makoto

“…β-Conglycinin is the major storage protein in soybeans. Pre-clinical animal models and human clinical studies have demonstrated the triglyceride-lowering…”
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Colonic epithelial cells express specific ligands for mucosal macrophage immunosuppressive receptors siglec-7 and -9 by Miyazaki, Keiko, Sakuma, Keiichiro, Kawamura, Yuki I, Izawa, Mineko, Ohmori, Katsuyuki, Mitsuki, Motoaki, Yamaji, Toshiyuki, Hashimoto, Yasuhiro, Suzuki, Akemi, Saito, Yukio, Dohi, Taeko, Kannagi, Reiji

“…Immune cells are known to express specific recognition molecules for cell surface glycans. However, mechanisms involved in glycan-mediated cell-cell…”
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Hypercholesterolemia and oxidative stress inhibit endothelial cell healing after arterial injury by Rosenbaum, Michael A., MD, Miyazaki, Keiko, MD, Graham, Linda M., MD

“…Objective Endothelial cell (EC) migration is essential for arterial healing after angioplasty. Oxidized low-density lipoproteins and oxidative stress decrease…”
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Altered sphingolipid metabolism induced by tumor hypoxia – New vistas in glycolipid tumor markers by Yin, Jun, Miyazaki, Keiko, Shaner, Rebecca L., Merrill, Alfred H., Kannagi, Reiji

“…Uncontrolled growth of malignant cells produces hypoxic regions in locally advanced tumors. Recently we showed that tumor hypoxia-induced transcription of…”
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Hypoxia Induces Adhesion Molecules on Cancer Cells: A Missing Link between Warburg Effect and Induction of Selectin-Ligand Carbohydrates by Koike, Tetsufumi, Kimura, Naoko, Miyazaki, Keiko, Yabuta, Tomonori, Kumamoto, Kensuke, Takenoshita, Seiichi, Chen, Jian, Kobayashi, Masanobu, Hosokawa, Masuo, Taniguchi, Akiyoshi, Kojima, Tetsuhito, Ishida, Nobuhiro, Kawakita, Masao, Yamamoto, Harumi, Takematsu, Hiromu, Suzuki, Akemi, Kozutsumi, Yasunori, Kanangi, Reiji, Fischer, Edmond H.

“…Cancer cells undergo distinct metabolic changes to cope with their hypoxic environment. These changes are achieved at least partly by the action of…”
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Hypoxic culture induces expression of sialin, a sialic acid transporter, and cancer-associated gangliosides containing non-human sialic acid on human cancer cells by JUN YIN, HASHIMOTO, Ayako, LIN, Chun-Hung, SATO, Chihiro, KITAJIMA, Ken, KANNAGI, Reiji, IZAWA, Mineko, MIYAZAKI, Keiko, CHEN, Guo-Yun, TAKEMATSU, Hiromu, KOZUTSUMI, Yasunori, SUZUKI, Akemi, FURUHATA, Kimio, CHENG, Feng-Leng

“…Tumor hypoxia figures heavily in malignant progression by altering the intracellular glucose metabolism and inducing angiogenic factor production, thus,…”
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Human B-lymphocytes Express α2-6-Sialylated 6-Sulfo-N-acetyllactosamine Serving as a Preferred Ligand for CD22/Siglec-2 by Kimura, Naoko, Ohmori, Katsuyuki, Miyazaki, Keiko, Izawa, Mineko, Matsuzaki, Yuji, Yasuda, Yosuke, Takematsu, Hiromu, Kozutsumi, Yasunori, Moriyama, Akihiko, Kannagi, Reiji

“…CD22/Siglec-2, an important inhibitory co-receptor on B-lymphocytes, is known to recognize α2-6-sialylated glycan as a specific ligand. Here we propose that…”
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Quantitative mapping of hepatic perfusion index using MR imaging: a potential reproducible tool for assessing tumour response to treatment with the antiangiogenic compound BIBF 1120, a potent triple angiokinase inhibitor by Miyazaki, Keiko, Collins, David J., Walker-Samuel, Simon, Taylor, Jane N., Padhani, Anwar R., Leach, Martin O., Koh, Dow-Mu

“…Hepatic metastases are arterially supplied, resulting in an elevated hepatic perfusion index (HPI). The purpose of this study was to use dynamic…”
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Epigenetic Silencing of the Sulfate Transporter Gene DTDST Induces Sialyl Lewisx Expression and Accelerates Proliferation of Colon Cancer Cells by YUSA, Akiko, MIYAZAKI, Keiko, KIMURA, Naoko, IZAWA, Mineko, KANNAGI, Reiji

“…Colon cancer cells express the carbohydrate determinant sialyl Lewis(x), while they exhibit markedly decreased the expression of its sulfated derivative,…”
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Antioxidant therapy reverses impaired graft healing in hypercholesterolemic rabbits by Rosenbaum, Michael A., MD, Miyazaki, Keiko, MD, Colles, Scott M, Graham, Linda M., MD

“…Objective Limited endothelial cell (EC) coverage and anastomotic intimal hyperplasia contribute to thrombosis and failure of prosthetic grafts. Lipid…”
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Ultrasonographic Findings and the Clinical Results of Treatment for Lymphedema by Niimi, Kiyoaki, Hirai, Masafumi, Iwata, Hirohide, Miyazaki, Keiko

“…We undertook this study using ultrasonography to examine structural changes occurring in the subcutaneous tissue with lymphedema. Ultrasonographic images were…”
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Postoperative renal function after elective abdominal aortic aneurysm repair requiring suprarenal aortic cross-clamping by Kudo, Fabio A, Nishibe, Toshiya, Miyazaki, Keiko, Murashita, Toshifumi, Yasuda, Keishu, Ando, Motomi, Nishibe, Masayasu

“…To examine postoperative renal function after suprarenal aortic cross-clamping performed without renal hypothermia in patients undergoing elective abdominal…”
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Methacarn Fixation: A Novel Tool for Analysis of Gene Expressions in Paraffin-Embedded Tissue Specimens by Shibutani, Makoto, Uneyama, Chikako, Miyazaki, Keiko, Toyoda, Kazuhiro, Hirose, Masao

“…To establish a quantitative method for analysis of gene expressions in small areas of tissue after paraffin embedding, preliminary validation experiments with…”
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2 --> 6 sialyl Le(a) antigen by Miyazaki, Keiko, Kannagi, Reiji

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Cilostazol suppresses neointimal hyperplasia in canine vein grafts by Kudo, Fabio A., Kondo, Yuka, Muto, Akihito, Miyazaki, Keiko, Dardik, Alan, Nishibe, Masayasu, Nishibe, Toshiya

“…Purpose To investigate whether cilostazol, a cyclic adenosine monophosphate (cAMP) phosphodiesterase inhibitor, suppresses intimal hyperplasia in canine vein…”
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