Search Results - "Miyawaki, Taichi"
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Impact of weight loss on treatment with PD-1/PD-L1 inhibitors plus chemotherapy in advanced non-small-cell lung cancer
Published in Supportive care in cancer (01-02-2022)“…Purpose Programmed cell death-1 (PD-1)/programmed death-ligand 1 (PD-L1) inhibitors plus chemotherapy have become the standard first line of treatment in…”
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Retrospective analysis of osimertinib re-challenge after osimertinib-induced interstitial lung disease in patients with EGFR-mutant non-small cell lung carcinoma
Published in Investigational new drugs (01-04-2021)“…Summary Osimertinib is a third-generation epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor (TKI) that has exhibited efficacy in patients with…”
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Association between the efficacy and immune-related adverse events of pembrolizumab and chemotherapy in non-small cell lung cancer patients: a retrospective study
Published in BMC cancer (06-10-2022)“…Abstract Background The combination of immune-checkpoint inhibitors with chemotherapy has become the standard of treatment for non-small cell lung cancer…”
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Efficacy of second-line chemotherapy in patients with pulmonary large cell neuroendocrine carcinoma
Published in Scientific reports (01-04-2024)“…The efficacy of second-line chemotherapy in patients with pulmonary large cell neuroendocrine carcinoma (LCNEC) is unclear. This study aimed to evaluate the…”
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Prognostic impact of pneumonitis after durvalumab therapy in patients with locally advanced non-small cell lung cancer
Published in Investigational new drugs (01-04-2022)“…Summary Background. Prognostic data on Japanese patients receiving durvalumab after chemoradiotherapy (CRT) for locally advanced non-small cell lung cancer…”
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Nivolumab‐induced radiation recall pneumonitis in non‐small‐cell lung cancer patients with thoracic radiation therapy
Published in Cancer science (01-02-2023)“…The role of previous thoracic radiation therapy as a risk factor of immune‐related pneumonitis is unclear. Furthermore, some patients develop radiation recall…”
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Significance of micro-EGFR T790M mutations on EGFR-tyrosine kinase inhibitor efficacy in non-small cell lung cancer
Published in Scientific reports (13-11-2023)“…Small amounts of epidermal growth factor receptor ( EGFR ) T790M mutation (micro-T790M), which is detected using droplet digital PCR (ddPCR) but not…”
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Proposing synchronous oligometastatic non–small‐cell lung cancer based on progression after first‐line systemic therapy
Published in Cancer science (01-01-2021)“…Despite the importance of accurate disease definitions for effective management and treatment decisions, there is currently no consensus on what constitutes…”
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Phase II study of multidisciplinary therapy combined with pembrolizumab for patients with synchronous oligometastatic non-small cell lung cancer TRAP OLIGO study (WJOG11118L)
Published in BMC cancer (18-10-2021)“…Synchronous oligometastatic non-small cell lung cancer (NSCLC) is generally characterised by the limited number of metastases at the time of diagnosis. Several…”
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Association between oligo-residual disease and patterns of failure during EGFR-TKI treatment in EGFR-mutated non-small cell lung cancer: a retrospective study
Published in BMC cancer (19-11-2021)“…Local ablative therapy (LAT) may be beneficial for patients with epidermal growth factor receptor (EGFR) mutated non-small cell lung cancer (NSCLC) with…”
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Long-term survival data of patients with limited disease small cell lung cancer: a retrospective analysis
Published in Investigational new drugs (01-04-2022)“…Summary Introduction : In patients with limited disease small cell lung cancer (LD-SCLC) treated with concurrent chemoradiotherapy (CCRT), long-term survival…”
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Association Between Clinical Tumor Burden and Efficacy of Immune Checkpoint Inhibitor Monotherapy for Advanced Non–Small-Cell Lung Cancer
Published in Clinical lung cancer (01-09-2020)“…Programmed cell death 1 (PD-1) inhibitors have become a standard treatment, albeit not completely effective, for patients with advanced non–small-cell lung…”
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Correction to: Prognostic impact of pneumonitis after durvalumab therapy in patients with locally advanced non‑small cell lung cancer
Published in Investigational new drugs (01-04-2022)Get full text
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Long-term outcomes in extensive disease small cell lung cancer patients treated without immune checkpoint inhibitors
Published in Japanese journal of clinical oncology (01-12-2021)“…Immune checkpoint inhibitors (ICIs) combined with chemotherapy have been approved as first-line treatment for patients with untreated extensive disease-small…”
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Detection of programmed cell death-ligand 1 using 22C3 antibody in patients with unresectable stage III non-small cell lung cancer receiving chemoradiotherapy
Published in International journal of clinical oncology (01-04-2021)“…Background The expression of programmed cell death-ligand 1 (PD-L1) is a biomarker for administering immune check point inhibitors in patients with advanced…”
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Rechallenge with previously administered epidermal growth factor receptor-tyrosine kinase inhibitors in EGFR-mutated non-small cell lung cancer with leptomeningeal metastasis
Published in Investigational new drugs (01-12-2021)“…Summary Objectives In EGFR -mutated non-small cell lung cancer (NSCLC) patients, approximately 80–90% of leptomeningeal metastasis (LM) develops after failed…”
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Second malignancy in advanced or recurrent non‐small cell lung cancer after the advent of molecular targeted drugs and immunotherapy
Published in Thoracic cancer (01-11-2024)“…Objectives This study aimed to investigate the characteristics of patients with recurrent or advanced non‐small cell lung cancer (NSCLC) treated with tyrosine…”
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Early Detection of Therapeutic Benefit from PD-1/PD-L1 Blockade in Advanced Lung Cancer by Monitoring Cachexia-Related Circulating Cytokines
Published in Cancers (11-02-2023)“…Cancer cachexia is associated with poor immunotherapeutic outcomes. This prospective observational study longitudinally evaluated the role of cachexia-related…”
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Heterogeneous Outcomes of Immune Checkpoint Inhibitor Rechallenge in Patients With NSCLC: A Systematic Review and Meta-Analysis
Published in JTO clinical and research reports (01-04-2022)“…Outcomes of immune checkpoint inhibitor (ICI) rechallenge in NSCLC remain uncertain. This study estimated the safety and efficacy of ICI rechallenge and…”
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Impact of losing adipose tissue on outcomes from PD‐1/PD‐L1 inhibitor monotherapy in non‐small cell lung cancer
Published in Thoracic cancer (01-05-2022)“…Background Adipose tissue induces inflammation, which desensitizes the efficacy of immunotherapy. However, several reports show that the therapeutic effect of…”
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