Search Results - "Miyawaki, Shingo"
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1
Role of epigenetic regulation in mammalian sex determination
Published in Current topics in developmental biology (2019)“…Mammalian sex determination is triggered by activation of the mammalian sex-determining gene, Sry, in a spatially and temporally controlled manner. Because…”
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2
Tumour resistance in induced pluripotent stem cells derived from naked mole-rats
Published in Nature communications (10-05-2016)“…The naked mole-rat (NMR, Heterocephalus glaber ), which is the longest-lived rodent species, exhibits extraordinary resistance to cancer. Here we report that…”
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3
Responses to pup vocalizations in subordinate naked mole-rats are induced by estradiol ingested through coprophagy of queen’s feces
Published in Proceedings of the National Academy of Sciences - PNAS (11-09-2018)“…Naked mole-rats form eusocial colonies consisting of a single breeding female (the queen), several breeding males, and sexually immature adults (subordinates)…”
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4
Visual and histological evaluation of the effects of trafermin in a dog oronasal fistula model
Published in Journal of Veterinary Medical Science (01-01-2022)“…The standard procedure to treat oronasal fistula in dogs requires tooth extraction to close the fistula; hence, the subject would lose its tooth. In this…”
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5
Characterization of brown adipose tissue thermogenesis in the naked mole-rat (Heterocephalus glaber), a heterothermic mammal
Published in Scientific reports (10-11-2020)“…The naked mole-rat (NMR) is a heterothermic mammal that forms eusocial colonies consisting of one reproductive female (queen), several reproductive males, and…”
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Suncus murinus as a novel model animal that is suitable for elucidating the mechanism of daily torpor
Published in Biomedical research (Tokyo) (15-04-2022)“…Torpor, a state of lowered body temperature due to active reduction of the metabolic rate, has potential medical benefits. The aim of this study was to…”
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Rescuing the aberrant sex development of H3K9 demethylase Jmjd1a-deficient mice by modulating H3K9 methylation balance
Published in PLoS genetics (26-09-2017)“…Histone H3 lysine 9 (H3K9) methylation is a hallmark of heterochromatin. H3K9 demethylation is crucial in mouse sex determination; The H3K9 demethylase Jmjd1a…”
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Erythritol inhibits the growth of periodontal-disease-associated bacteria isolated from canine oral cavity
Published in Heliyon (01-08-2022)“…Periodontal disease (PD) is the most common oral disease that is caused by infection with periodontal-disease-associated bacteria (PDAB) such as Porphyromonas…”
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Teratoma Formation Assay for Assessing Pluripotency and Tumorigenicity of Pluripotent Stem Cells
Published in Bio-protocol (20-08-2017)“…Pluripotent stem cells such as induced pluripotent stem cells (iPSCs) and embryonic stem cells (ESCs) form teratomas when transplanted into immunodeficient…”
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10
Portal Vein Aneurysm in a Dog
Published in Journal of Veterinary Medical Science (01-09-2012)“…Portal vein aneurysm (PVA) is a rare abnormal dilatation of the portal vein, which has not been reported in dogs. We describe the findings of ultrasound and…”
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First Case of Salivary Mucocele Originating from the Minor Salivary Gland of the Soft Palate in a Dog
Published in Journal of Veterinary Medical Science (01-01-2012)“…We found a case of salivary mucocele that originated in the minor salivary gland (palatine gland) of the soft palate in a dog. At first admission, the soft…”
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12
The mouse Sry locus harbors a cryptic exon that is essential for male sex determination
Published in Science (American Association for the Advancement of Science) (02-10-2020)“…Two rather than one For several decades, it has been believed that the mammalian sex-determining gene Sry contains a single exon. Miyawaki et al. have now…”
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13
Expression patterns of prosaposin and its receptors, G protein-coupled receptor (GPR) 37 and GPR37L1, in the mouse olfactory organ
Published in Tissue & cell (01-06-2023)“…Prosaposin is a glycoprotein conserved widely in vertebrates, because it is a precursor for saposins that are required for normal lysosomal function and thus…”
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Cellular senescence induction leads to progressive cell death via the INK4a‐RB pathway in naked mole‐rats
Published in The EMBO journal (15-08-2023)“…Naked mole‐rats (NMRs) have exceptional longevity and are resistant to age‐related physiological decline and diseases. Given the role of cellular senescence in…”
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15
Visual and histological evaluation of the effects of trafermin in a dog oronasal fistula model
Published in Journal of Veterinary Medical Science (2021)“…The standard procedure to treat oronasal fistula in dogs requires tooth extraction to close the fistula; hence, the subject would lose its tooth. In this…”
Get full text
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